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DOI: 10.1039/D6FO00323K

The role of vagus nerve stimulation in modulating Parkinson’s disease via the microbiota-gut-brain axis: a comprehensive review

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DOI: 10.3389/fneur.2025.1643305

Metabolic Profiling of a Mediterranean-Inspired (Poly)phenol-Rich Mixture in the Brain: Perfusion Effect and In Vitro Blood–Brain Barrier Transport Validation

María Ángeles Ávila-Gálvez, Beatriz Garay-Mayol, Alicia Marín, María Alexandra Brito, Juan Antonio Giménez-Bastida, Juan Carlos Espín and Antonio González-Sarrías

J. Agric. Food Chem., 2025, 73, 11056
DOI: 10.1021/acs.jafc.5c02288

Functional Food Nutrients, Redox Resilience Signaling and Neurosteroids for Brain Health

Maria Scuto, Miroslava Majzúnová, Gessica Torcitto, Silvia Antonuzzo, Francesco Rampulla, Eleonora Di Fatta and Angela Trovato Salinaro

IJMS, 2024, 25, 12155
DOI: 10.3390/ijms252212155

(Poly)phenol and methylxanthine metabolites and their association with cognitive and cardiometabolic health in older people

Yong Li, Melanie Le Sayec, Yifan Xu, Anne Katrine Bergland, Khadija Khalifa, Chiara de Lucia, Dag Aarsland, Rachel Gibson and Ana Rodriguez-Mateos

The Journal of Nutritional Biochemistry, 2026, 153, 110300
DOI: 10.1016/j.jnutbio.2026.110300

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Maroua Jalouli, Md Ataur Rahman, Partha Biswas, Hasanur Rahman, Abdel Halim Harrath, In-Seon Lee, Sojin Kang, Jinwon Choi, Moon Nyeo Park and Bonglee Kim

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DOI: 10.3389/fphar.2025.1492517

Brain organoids in environmental neurotoxicology: applications, mechanisms, and future perspectives

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Cell Biol Toxicol, 2026, 42
DOI: 10.1007/s10565-026-10161-8

Plant-derived bioactive compounds and their possible role in sleep and insomnia management: Insights from gut-brain axis modulation and advanced delivery systems

Zhiwei Li, Yong Cheng, Dandan Ma, Peng Deng, Zhaojun Wang, Qiuming Chen, Maomao Zeng, Jie Chen, Fengxian Guo, Zongping Zheng, Benu Adhikari and Zhiyong He

Trends in Food Science & Technology, 2026, 172, 105708
DOI: 10.1016/j.tifs.2026.105708

Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy

Shiyu Zhu, Qinming Yu, Yuhan Jiang, Qiuyue Zu and Wendan Pang

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DOI: 10.3389/fnut.2026.1725745

Plant Polyphenols as Heart’s Best Friends: From Health Properties, to Cellular Effects, to Molecular Mechanisms of Action

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IJMS, 2025, 26, 915
DOI: 10.3390/ijms26030915