Therapeutic Potential of Microneedle Assisted Drug Delivery for Wound Healing: Current State of the Art, Challenges, and Future Perspective

Devesh Kumar, Shubham Pandey, Jailani Shiekmydeen, Mohit Kumar, Shruti Chopra and Amit Bhatia

AAPS PharmSciTech, 2025, 26
DOI: 10.1208/s12249-024-03017-z

Chitosan‐Based Hydrogels as Antibacterial/Antioxidant/Anti‐Inflammation Multifunctional Dressings for Chronic Wound Healing

Jingchen Xu, Lili Chang, Yuhuan Xiong and Qiang Peng

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202401490

Comprehensive developmental investigation on simvastatin enriched bioactive film forming spray using the quality by design paradigm: a prospective strategy for improved wound healing

Vrushali N. Patel, Heta V. Patel, Kashish Agrawal, Ishika Soni, Pranav Shah, Shubhada V. Mangrulkar, Milind J. Umekar and Manisha S. Lalan

Journal of Drug Targeting, 2024, 32, 1139
DOI: 10.1080/1061186X.2024.2382405

Recent Applications of Chitosan and Its Derivatives in Antibacterial, Anticancer, Wound Healing, and Tissue Engineering Fields

Saeid Mezail Mawazi, Mohit Kumar, Noraini Ahmad, Yi Ge and Syed Mahmood

Polymers, 2024, 16, 1351
DOI: 10.3390/polym16101351

Phytogenic metal nanoparticles: A promising frontier in natural medicine for inflammation and wound repair

Sweta Mishra and Chandana Mohanty

Next Research, 2025, 2, 100160
DOI: 10.1016/j.nexres.2025.100160

Revolutionizing nanomedicine: Expanding horizons of nanoemulsions in drug delivery and beyond

Mohit Kumar, Nitasha Chauhan, Devesh Kumar, Syed Mahmood, Shruti Chopra and Amit Bhatia

Journal of Dispersion Science and Technology, 2024, 1
DOI: 10.1080/01932691.2024.2369835

Gabapentin loaded nano-emulsion for the effective treatment of peripheral neurological pain: Formulation, characterization, and ex vivo studies

Bhavna, Mohit Kumar, Ayesha Siddiqui, Syed Mahmood, Pooja Jain, M. Aamir Mirza and Zeenat Iqbal

Next Nanotechnology, 2026, 9, 100354
DOI: 10.1016/j.nxnano.2025.100354

Biomedical Applications and Properties of Sericin-Based Microcapsules in Drug Delivery and Tissue Engineering

Maryam Ilyas, Aamir Ali, Hafiz Muhammad Tahir, Ayesha Muzamil, Rimsha Yaqoob and Zoya Abid

Regen. Eng. Transl. Med., 2025
DOI: 10.1007/s40883-025-00466-1

Therapeutic potential of traditional Chinese medicine loaded nanocarriers in wound management: Current status and their future perspective

Jitendra Gupta, Devesh Kumar, Reena Gupta, Diksha Diwakar, Kumari Shanno, Arpan Kumar Tripathi, Akshay Kumar and Mohit Kumar

Pharmacological Research - Modern Chinese Medicine, 2025, 15, 100622
DOI: 10.1016/j.prmcm.2025.100622

Optimized Hesperidin-Loaded Lipid Nanoparticles with Tea Tree Oil for Enhanced Wound Healing: Formulation, Characterization, and Evaluation

Borros Arneth, Rehab Abdelmonem, Mohamed A. El-Nabarawi, Mahmoud Hassan Teaima, Kareem Omar Rashwan, Mohamed A. Soliman and Inas Essam Ibrahim Al-Samadi

Pharmaceuticals, 2025, 18, 290
DOI: 10.3390/ph18030290

Thermo-Sensitive Polymeric Networks for Next-Generation Wound Management: A Review

Akshay Kumar, Prachee Nirmale, Suresh Babu Kondaveeti, Arpan Kumar Tripathi, Jailani Shiekmydeen, Sagar Nanaso Salunkhe, Gurjeet Singh Thakur and Mohit Kumar

AAPS PharmSciTech, 2026, 27
DOI: 10.1208/s12249-026-03423-5

Exploring the Therapeutic Potential of Bromelain-Infused Proposomal Hydrogels for Accelerating Burn Wound Recovery: In Vivo and In Vitro Insights

Yashashvi Jaiswal, Vishwambhar Mishra, Shailendra K Saraf and Priyanka Maurya

J Pharm Innov, 2025, 20
DOI: 10.1007/s12247-025-10155-9

Development of Emodin Nanocrystal‐Loaded Hydrogel Patch for Rapid Wound Repair

Devyani Yenurkar, Anoushka Shrivastava, Snehasish Mandal, Vivek Kumar, Lipi Pradhan, Shikha Tripathi, Avanish Singh Parmar, Arnab Sarkar and Sudip Mukherjee

Macromolecular Bioscience, 2026, 26
DOI: 10.1002/mabi.202500581

Exploring Innovative Approaches in Type-2 Diabetes Management: A Comprehensive Review on Nano-carriers and Transdermal Drug Delivery

Nitasha Chauhan, Mohit Kumar, Karan Kumar, Shruti Chopra and Amit Bhatia

CPD, 2024, 30, 1725
DOI: 10.2174/0113816128313325240513113840

Development of 3D-Printed chitosan-based hydrogels rich in Centella asiatica extract for enhanced wound healing applications

Katarzyna Witkowska, Magdalena Paczkowska-Walendowska, Andrzej Miklaszewski, Tomasz Plech, Bożena Michniak-Kohn, Ewelina Swora-Cwynar and Judyta Cielecka-Piontek

Journal of Drug Delivery Science and Technology, 2025, 111, 107143
DOI: 10.1016/j.jddst.2025.107143

Biopolymer based nanoparticles and their therapeutic potential in wound healing – A review

Mohit Kumar, Syed Mahmood, Shruti Chopra and Amit Bhatia

International Journal of Biological Macromolecules, 2024, 267, 131335
DOI: 10.1016/j.ijbiomac.2024.131335

Advances in chitosan based nanocarriers for targetted wound healing therapies: a review

S Naveedunissa, R Meenalotchani, M Manisha, S Ankul Singh, S Nirenjen, K Anitha, N Harikrishnan and Bhupendra G Prajapati

Carbohydrate Polymer Technologies and Applications, 2025, 11, 100891
DOI: 10.1016/j.carpta.2025.100891

AQbD enabled method development and quantification of asiaticoside in foam-based formulations

Mohit Kumar, Anjali Pant, Shruti Chopra and Amit Bhatia

Accred Qual Assur, 2025, 30, 67
DOI: 10.1007/s00769-024-01608-8

Advancements of thermoelectric nanomaterials in ROS-mediated broad-spectrum antibacterial therapies for wound healing

Shiyu Jia, Cai Qi, Shengduo Xu, Lei Yang and Qiang Sun

Journal of Materials Science & Technology, 2025, 225, 212
DOI: 10.1016/j.jmst.2024.11.039

Development of chitosan-based Centella asiatica nanoparticles and their immunostimulatory activity through macrophage phagocytosis assay

Agus Pratiwi, Retno Sari, Aty Widyawaruyanti, Yusuf Alif Pratama, Suryani Saallah and Sonia Andreia Oliveira Santos

J. Umm Al-Qura Univ. Med. Sci., 2026, 12
DOI: 10.1007/s44361-026-00031-7

Progress in Drug Delivery Systems Based on Nanoparticles for Improved Glioblastoma Therapy: Addressing Challenges and Investigating Opportunities

Md Ataur Rahman, Maroua Jalouli, Mahesh Kumar Yadab and Mohammed Al-Zharani

Cancers, 2025, 17, 701
DOI: 10.3390/cancers17040701

Olive leaf extract-based eye drop formulations for corneal wound healing

Chiara Migone, Luca Cerri, Bárbara Ferreira, Angela Fabiano, Sara Parri, Andrea Mezzetta, Lorenzo Guazzelli, Anna Maria Piras, Ylenia Zambito and Bruno Sarmento

Journal of Drug Delivery Science and Technology, 2025, 110, 107026
DOI: 10.1016/j.jddst.2025.107026

Multiscale design of chemically crosslinked dextran hydrogels from bulk scaffolds to microgels and nanofibers

Parisa Nikpour, Hamed Salimi-Kenari, Mohammad Imani and Mohanna Arab Khazaeli

Discov Polym, 2026, 3
DOI: 10.1007/s44347-026-00038-8

Therapeutic Potential of Nanocarrier Mediated Delivery of Peptides for Wound Healing: Current Status, Challenges and Future Prospective

Mohit Kumar, Dikshant Kumar, Devesh Kumar, Yogesh Garg, Shruti Chopra and Amit Bhatia

AAPS PharmSciTech, 2024, 25
DOI: 10.1208/s12249-024-02827-5

Smart Stings of Nature: Harnessing Microneedles Assisted Targeted Phytoconstituent Delivery for Dermatological Disorders

Akshay Kumar, Suresh Babu Kondaveeti, Arpan Kumar Tripathi, Mohit Agrawal, Thakur Gurjeet Singh, Devesh Kumar and Mohit Kumar

AAPS PharmSciTech, 2026, 27
DOI: 10.1208/s12249-025-03311-4

Foam-Based Drug Delivery Systems for Skin Disorders: A Comprehensive Review

Syrsulu Myrzagulova, Zhexenova Azhar N, Mohit Kumar, Devesh Kumar and Akshay Kumar

AAPS PharmSciTech, 2025, 26
DOI: 10.1208/s12249-025-03098-4

Development of polypropylene wound dressing coated with chitosan and Estradiol Valerate: A novel approach to chronic wound care

Kimia Sari, Ladan Dayani, Safoora Poorirani, Parisa Heydari, Nassim Ghaffari Tabrizi-Wizsy and Sayed Abolfazl Mostafavi

International Journal of Pharmaceutics, 2026, 687, 126386
DOI: 10.1016/j.ijpharm.2025.126386

Dual-domain engineered exosome-based self-powered microneedle delivery platform for the treatment of infected wounds

Shanguo Zhang, Tianyi Jiang, Depeng Yang, Liangyu Cao, Ming Li, Jiachao Tang, Qi Gu, Aitong Xu, Yu Li and Hongyuan Jiang

Materials Today Bio, 2025, 35, 102383
DOI: 10.1016/j.mtbio.2025.102383

Biosynthesized lincomycin loaded copper oxide nanoparticles using cichorium intybus based thin film spray for enhanced antibacterial and wound healing

Sajid Ali, Rashna Mirza, Zubariya Amjad, Muhammad Ilyas, Salman Khan, Shefaat Ullah Shah, Saqib Jahan, Abdullah R. Alanzi, Moneerah J. Alqahtani, Jawaher H. Alqahtani, Stephane Gibaud and Kifayat Ullah Shah

Journal of Drug Delivery Science and Technology, 2025, 114, 107570
DOI: 10.1016/j.jddst.2025.107570

Natural Products for Improving Soft Tissue Healing: Mechanisms, Innovations, and Clinical Potential

Adina Alberts, Ioana Alexandra Lungescu, Adelina-Gabriela Niculescu and Alexandru Mihai Grumezescu

Pharmaceutics, 2025, 17, 758
DOI: 10.3390/pharmaceutics17060758

Therapeutic potential of spray-based delivery system for the treatment of dermatological disorders: clinical insights and formulation advances

Devesh Kumar, Prachee Nirmale, Suresh Babu Kondaveeti, Mohit Agrawal, Thakur Gurjeet Singh, Ankit Awasthi and Mohit Kumar

International Journal of Pharmaceutics, 2026, 695, 126766
DOI: 10.1016/j.ijpharm.2026.126766

Investigation of Tannic Acid Crosslinked PVA/PEI-Based Hydrogels as Potential Wound Dressings with Self-Healing and High Antibacterial Properties

Nimet Rumeysa Karakuş, Serbülent Türk, Gamze Guney Eskiler, Marat Syzdykbayev, Nurbol O. Appazov and Mahmut Özacar

Gels, 2024, 10, 682
DOI: 10.3390/gels10110682

Signalling pathways triggering therapeutic marine algae-derived natural polysaccharides for effective wound healing: A recent review

Suresh Babu Kondaveeti, Arpan Kumar Tripathi, Devesh Kumar, Akshay Kumar, Thakur Gurjeet Singh, Syed Mahmood, Kajal Ghosal, Ankit Awasthi and Mohit Kumar

Carbohydrate Polymers, 2025, 369, 124253
DOI: 10.1016/j.carbpol.2025.124253

Aqueous-softened, organic solvent-free hot-melt extrusion of Centella asiatica biomass into multifunctional bio-based materials

Han-Sol You, Jun-Ho Lee, Bo-Yun Choi, Man-Sop Shim and Jong-Suep Baek

Industrial Crops and Products, 2026, 248, 123568
DOI: 10.1016/j.indcrop.2026.123568

Development and optimization of asiaticoside co-crystal-loaded transdermal patch for topical therapy

Suhas Shivaji Siddheshwar, Omkar Atkare, Arti Changdev Ghorpade, Rajashri Ghogare and Someshwar Dattatraya Mankar

Naunyn-Schmiedeberg's Arch Pharmacol, 2026, 399, 8443
DOI: 10.1007/s00210-025-04915-0

Centella asiatica: An ethnobotanical treasure with promising anticancer properties

Sanjukta Sen, Siuli Sen and Dipanjan Karati

Pharmacological Research - Natural Products, 2026, 10, 100490
DOI: 10.1016/j.prenap.2026.100490

A recent review on smart sensor-integrated wound dressings: Real-time monitoring and on-demand therapeutic delivery

Mohit Kumar, Pranshul Sethi, Jailani Shiekmydeen, Sonali Rastogi, Syed Mahmood, Shruti Chopra, Sabu Thomas, Devesh Kumar and Amit Bhatia

International Journal of Biological Macromolecules, 2025, 313, 144251
DOI: 10.1016/j.ijbiomac.2025.144251

Unlocking healing codes: Nanocarriers and signalling pathways modulation for wound repair

Akshay Kumar, Devesh Kumar, Suresh Babu Kondaveeti, Kumaraswamy Dabburu, Ankit Awasthi, Thakur Gurjeet Singh, Sabu Thomas and Mohit Kumar

Materials Today Communications, 2025, 49, 114149
DOI: 10.1016/j.mtcomm.2025.114149

AQbD enabled analytical method development and validation for simultaneous estimation of Asiaticoside (AC) and Chlorhexidine (CHX) in nanostructured lipid carriers

Akshay Kumar, Abhishek Chauhan, Devesh Kumar, Arpan Kumar Tripathi, Ankit Awasthi, Thakur Gurjeet Singh, Suresh Babu Kondaveeti and Mohit Kumar

J Pharm Innov, 2026, 21
DOI: 10.1007/s12247-026-10506-0

pH-responsive mupirocin-loaded hybrid nanoparticles in hydrogel and film forming spray against resistant bacterial wound infections

Shahid Ali Khan, Naveed Ahmed, Dildar Khan, Ayesha Bibi and Asim ur Rehman

Journal of Drug Delivery Science and Technology, 2024, 101, 106187
DOI: 10.1016/j.jddst.2024.106187

Asiaticoside-Loaded Multifunctional Bioscaffolds for Enhanced Hyperglycemic Wound Healing

Raniya Razif, Nur Izzah Md Fadilah, Haslina Ahmad, Daniel Looi Qi Hao, Manira Maarof and Mh Busra Fauzi

Biomedicines, 2025, 13, 277
DOI: 10.3390/biomedicines13020277