From lab to field: revolutionizing antibiotic detection with aptamer-based biosensors

Dipanjan Das, Joydeep Chakraborty, Pankaj Mandal, Rittick Mondal and Amit Kumar Mandal

RSC Adv., 2025, 15, 18920
DOI: 10.1039/D5RA02100F

Construction of colorimetric sensor arrays using steel slag-based composites for highly sensitive detection of tetracycline antibiotics

Xin Zhao, Zhaohui Zhang and Jiaxiang Liu

Anal. Methods, 2024, 16, 5555
DOI: 10.1039/D4AY00754A

Light-up split aptamers: binding thermodynamics and kinetics for sensing

Yichen Zhao, Nikesh Patel, Peihuan Sun, Karen Faulds, Duncan Graham and Juewen Liu

Analyst, 2023, 148, 5612
DOI: 10.1039/D3AN01368E

A DNA aptamer for trivalent lanthanide ions with low nanomolar affinity

Jin Wang, Xin Wang, Xuesong Li, Xiangmei Li, Hongtao Lei and Juewen Liu

Inorg. Chem. Front., 2025, 12, 4494
DOI: 10.1039/D5QI00391A

A perovskite‐based electrochemiluminescence aptasensor for tetracycline screening

Yuxin Chen, Xinyi Zhong, Qiling Yang, Huiping Chen, Nan Hao and Shanwen Hu

Luminescence, 2024, 39
DOI: 10.1002/bio.4717

Harnessing a Fluorescent Nucleobase Surrogate for Supramolecular FRET-Aptamer Detection and Target-Site Mapping

Karley J. L. Zimmer, Ryan E. Johnson, Hunter Little, Jean Duhamel and Richard A. Manderville

ACS Sens., 2025, 10, 1822
DOI: 10.1021/acssensors.4c02772

Europium coordination polymers-based ratiometric ratiometric fluorescent probe for portable visual detection and discrimination of tetracyclines

Jibing Chen, Rui Dai, Fengqiu Sun, Yan Zhao, Weiheng Kong and Rong-Mei Kong

Microchemical Journal, 2025, 218, 115308
DOI: 10.1016/j.microc.2025.115308

A DNA Aptamer for 2‐Aminopurine: Binding‐Induced Fluorescence Quenching

Meheta Datta and Juewen Liu

Chemistry An Asian Journal, 2024, 19
DOI: 10.1002/asia.202400817

Rethinking the Role of AuNPs in Colorimetric Aptasensors: Dominant Nonspecific Interactions with Antibiotics over Aptamer Recognition

Zhuoer Chen, Ying Yang, Yaning Liang, Xinge Cui, Luwei Chai, Xue Wang and Tao Le

ACS Sens., 2026, 11, 522
DOI: 10.1021/acssensors.5c03309

Fluorometric sensing probe using carbon quantum dots for selective detection of doxycycline antibiotic

Deepak Kumar, Subhash Chandra, Vivek Kumar, Pradeep Kumar Yadav and Syed Hadi Hasan

Carbon Lett., 2025, 35, 895
DOI: 10.1007/s42823-024-00839-6

Nanomaterials-based aptasensors for rapid detection and early warning of key food contaminants: A review

Min Ouyang, Ting Liu, Xiaomin Yuan, Can Xie, Kun Luo and Liyi Zhou

Food Chemistry, 2025, 462, 140990
DOI: 10.1016/j.foodchem.2024.140990

Recent advances in optical sensing for tetracycline antibiotics

Mingcong Rong, Yi Huang, Chunxiao Lin, Limin Lai, Yanfang Wu and Li Niu

TrAC Trends in Analytical Chemistry, 2024, 178, 117839
DOI: 10.1016/j.trac.2024.117839

Aptamer-based tri-mode sensing for detecting oxytetracycline mediated by SYBR Green I and functionalized Au nanoparticles

Yifan Shao, Xiaoxiao Qi, Hongliang Wang, Bo Tang, Yongqiang Cheng, Ziwei Zhang, Xi Zhang and Meijia Zhu

Biosensors and Bioelectronics, 2025, 270, 116930
DOI: 10.1016/j.bios.2024.116930

Detecting tetracycline with one drop of water in a zeolitic sensor through visualized cyan light

Xingai Ge, Yanqiu Chen, Na Zhang, Xiyuan Tong, Yifeng E, Li Li, Kun Qian and Zhuozhe Li

Microchemical Journal, 2025, 218, 115211
DOI: 10.1016/j.microc.2025.115211

Kinetic and Affinity Profiling Rare Earth Metals Using a DNA Aptamer

Jin Wang, Yunus A. Kaiyum, Xiangmei Li, Hongtao Lei, Philip E. Johnson and Juewen Liu

J. Am. Chem. Soc., 2025, 147, 1831
DOI: 10.1021/jacs.4c13768

Dual-enhanced quantification of tetracyclines in feeds via aptamer-amplified excitation–emission matrix fluorescence and PARAFACM resolution

Yan-Ran Zhang, Wei Li, Shi-Lu You, Xiao-Zhi Wang, Tong Wang, Hai-Long Wu and Ru-Qin Yu

Microchemical Journal, 2026, 221, 116769
DOI: 10.1016/j.microc.2025.116769

Aptamer-based sensing in food science: precision tools for enhanced consumer safety and perception

Dipanjan Das, Rittick Mondal, Pankaj Mandal, Debnirmalya Gangopadhyay and Amit K Mandal

Current Opinion in Food Science, 2025, 66, 101363
DOI: 10.1016/j.cofs.2025.101363

Characterization of the Binding Properties of Ten Aptamers Using the Intrinsic Fluorescence of Oxytetracycline

Yichen Zhao, Biwen Gao and Juewen Liu

ChemistryOpen, 2024, 13
DOI: 10.1002/open.202300250

High-Affinity Three-Way Junction Aptamers for Sensing Cationic Polymyxin Antibiotics

Sihan Wang, Jiayi Liang, Zhanhui Wang, Jianzhong Shen, Haiyang Jiang and Juewen Liu

Anal. Chem., 2026, 98, 9133
DOI: 10.1021/acs.analchem.5c07567

Sensor array and color-coded test paper tongue based on multivariate cross-responsive AIEgen functionalized bimetallic lanthanide infinite coordination polymers: Toward smart identification and systematic analysis of antibiotics

Junxuan Zhu, Yuanyue Wu, Chenyi Xue, Manman Zhang, Yiling Zhang, Xuefei Zhang, Tianshu Zhou and Jingjing Deng

Chemical Engineering Journal, 2024, 500, 156839
DOI: 10.1016/j.cej.2024.156839

An Ultrahigh Affinity DNA Aptamer for Quinine and Its Intrinsic Fluorescence Based Label‐Free Detection

Meheta Datta, Yunus A. Kaiyum, Philip E. Johnson and Juewen Liu

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202403435

Interfacing DNA and Aptamers with Gold Nanoparticles: From Fundamental Colloid and Interface Sciences to Biosensors

Yuzhe Ding and Juewen Liu

Chin. J. Chem., 2024, 42, 2391
DOI: 10.1002/cjoc.202400113

Aptamer-based modulation of the UiO-66-NH2@Ag SERS sensor: an ultrasensitive multi-residue specific assay for tetracycline antibiotics

Xiaoying Yang, Qian Liu, Shiyu Wei, Juan Tao, Tianxiang Li, Shunlin Zhang, Chao Kang, Yuegang Chen, Dongmei Chen and Wanliang Yang

Food Control, 2026, 189, 112249
DOI: 10.1016/j.foodcont.2026.112249

Ratiometric, 3D Fluorescence Spectrum with Abundant Information for Tetracyclines Discrimination via Dual Biomolecules Recognition and Deep Learning

Tiancheng Yang, Bin Yang, Zhen Tian, Guanyu Zhu and Ye Peng

Anal. Chem., 2025, 97, 6745
DOI: 10.1021/acs.analchem.4c07061

Kinetic ITC of DNA Aptamers Binding for Small Molecules and Implications for Binding Assays and Biosensors

Yuzhe Ding and Juewen Liu

ChemBioChem, 2024, 25
DOI: 10.1002/cbic.202400225

Ultrasensitive detection of tetracycline using the disruption of crosslink-enhanced emission and inner-filter effect-induced phosphorescence quenching of carbonized polymer dots

Cheng-Yu Zhao, Wei-Bin Tseng, Kai-Hsin Hung and Wei-Lung Tseng

Biosensors and Bioelectronics, 2025, 279, 117409
DOI: 10.1016/j.bios.2025.117409

Construction of sulfur-doped porous g-C3N4/Bi2WO6 S-scheme heterojunction with efficient photocatalytic degradation of oxytetracycline

Yu Zhu, Ling Wang, Chujun Feng, Man Zhou, Yanan Wang, Song Xu and Zhongyu Li

Journal of Alloys and Compounds, 2025, 1040, 183652
DOI: 10.1016/j.jallcom.2025.183652