Microfluidic methods for the diagnosis of acute respiratory tract infections

Kan-Zhi Liu, Ganghong Tian, Alex C.-T. Ko, Matthias Geissler, Lidija Malic, Byeong-Ui Moon, Liviu Clime and Teodor Veres

Analyst, 2025, 150, 9
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Multiple on-line active valves based centrifugal microfluidics for dynamic solid-phase enrichment and purification of viral nucleic acid

Shunji Li, Chao Wan, Yujin Xiao, Changgen Liu, Xudong Zhao, Ying Zhang, Huijuan Yuan, Liqiang Wu, Chungen Qian, Yiwei Li, Peng Chen and Bi-Feng Liu

Lab Chip, 2024, 24, 3158
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Sample-to-answer centrifugal microfluidic droplet PCR platform for quantitation of viral load

Lidija Malic, Liviu Clime, Byeong-Ui Moon, Christina Nassif, Dillon Da Fonte, Daniel Brassard, Ljuboje Lukic, Matthias Geissler, Keith Morton, Denis Charlebois and Teodor Veres

Lab Chip, 2024, 24, 4755
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Recent advances in point-of-care testing of COVID-19

Sungwoon Lee, Liyan Bi, Hao Chen, Dong Lin, Rongchao Mei, Yixuan Wu, Lingxin Chen, Sang-Woo Joo and Jaebum Choo

Chem. Soc. Rev., 2023, 52, 8500
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A combined digital microfluidic test for assessing infection and immunity status for viral disease in saliva

N. Sathishkumar, Jose Gilberto Camacho Valenzuela, Nguyen H. Le, Anthony K. C. Yong, Martin A. Rossotti, Joshua Dahmer, Alexandros A. Sklavounos, Martin Plante, Daniel Brassard, Lidija Malic, Anna N. Moraitis, Ruzica Biga, Imane El Idrissi, Jamshid Tanha, Jean Labrecque, Teodor Veres and Aaron R. Wheeler

Lab Chip, 2025, 25, 3197
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Adeno-associated viral vector purification using a centrifugal microfluidic system: towards workflow automation for low-volume sample processing

Matthias Geissler, Lidija Malic, Liviu Clime, Dillon Da Fonte, Christina Nassif, Mojra Janta-Polczynski, Caroline Miville-Godin, Daniel Brassard, Nasha Nassoury, Richard Gingras, Nazila Nazemi-Moghaddam, Parminder Singh Chahal, Rénald Gilbert and Teodor Veres

Lab Chip, 2026
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Digital microfluidics with distance-based detection – a new approach for nucleic acid diagnostics

Man Ho, N. Sathishkumar, Alexandros A. Sklavounos, Jianxian Sun, Ivy Yang, Kevin P. Nichols and Aaron R. Wheeler

Lab Chip, 2024, 24, 63
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Centrifugal microfluidic system for colorimetric sample-to-answer detection of viral pathogens

Matthias Geissler, Daniel Brassard, Nadine Adam, Neda Nasheri, Ana Victoria C. Pilar, Kyle Tapp, Liviu Clime, Caroline Miville-Godin, Maxence Mounier, Christina Nassif, Ljuboje Lukic, Lidija Malic, Nathalie Corneau and Teodor Veres

Lab Chip, 2024, 24, 668
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Automated centrifugal microfluidic system for the preparation of adaptor-ligated sequencing libraries

Jimin Guo, Daniel Brassard, Nadine Adam, Adrian J. Verster, Julie A. Shay, Caroline Miville-Godin, Mojra Janta-Polczynski, Jason Ferreira, Maxence Mounier, Ana V. Pilar, Kyle Tapp, Adam Classen, Matthew Shiu, Denis Charlebois, Nicholas Petronella, Kelly Weedmark, Nathalie Corneau and Teodor Veres

Lab Chip, 2024, 24, 182
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Sample preparation and detection methods in point-of-care devices towards future at-home testing

George Adedokun, Morteza Alipanah and Z. Hugh Fan

Lab Chip, 2024, 24, 3626
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Rapid microfluidics prototyping through variotherm desktop injection molding for multiplex diagnostics

Gianmarco D. Suarez, Steevanson Bayer, Yuki Yu Kiu Tang, Domenick A. Suarez, Peter Pak-Hang Cheung and Stefan Nagl

Lab Chip, 2023, 23, 3850
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Online determination of elements in pure iron by non-weighing micro-reaction with inductively coupled plasma optical emission spectrometry

Dandan Su, Xuejing Shen, Jingyu Hu, Yunhai Jia, Haina Zhao, Yanxia Hou, Guowu Yang, Fei Lin and Haizhou Wang

Analytica Chimica Acta, 2025, 1372, 344434
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Optimization of Reverse Transcription Loop-Mediated Isothermal Amplification for In Situ Detection of SARS-CoV-2 in a Micro-Air-Filtration Device Format

Jacob Fry, Jean Y. H. Lee, Julie L. McAuley, Jessica L. Porter, Ian R. Monk, Samuel T. Martin, David J. Collins, Gregory J. Barbante, Nicholas J. Fitzgerald and Timothy P. Stinear

ACS Omega, 2024, 9, 40832
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Microfluidics for COVID-19: From Current Work to Future Perspective

Qi Li, Xingchen Zhou, Qian Wang, Wenfang Liu and Chuanpin Chen

Biosensors, 2023, 13, 163
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Syphilis point-of-care tests (POCTs): Implementation considerations in Canada

Kathleen Whyte, Andrea Chittle and Raymond SW Tsang

Journal of the Association of Medical Microbiology and Infectious Disease Canada, 2024, 9, 208
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μPADs on Centrifugal Microfluidic Discs for Rapid Sample-to-Answer Salivary Diagnostics

Shixian Liu, Yuting Hou, Zirui Li, Chenyu Yang and Guozhen Liu

ACS Sens., 2023, 8, 3520
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Rapid on-site nucleic acid testing: On-chip sample preparation, amplification, and detection, and their integration into all-in-one systems

Jingwen Wang, Han Jiang, Leiming Pan, Xiuying Gu, Chaogeng Xiao, Pengpeng Liu, Yulong Tang, Jiehong Fang, Xiaoqian Li and Chenze Lu

Front. Bioeng. Biotechnol., 2023, 11
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Microfluidic-based technologies for diagnosis, prevention, and treatment of COVID-19: recent advances and future directions

E. Alperay Tarim, Muge Anil Inevi, Ilayda Ozkan, Seren Kecili, Eyup Bilgi, M. Semih Baslar, Engin Ozcivici, Ceyda Oksel Karakus and H. Cumhur Tekin

Biomed Microdevices, 2023, 25
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AI-empowered visualization of nucleic acid testing

Zehua Lu, Xiaogang Wang and Junge Chen

Life Sciences, 2024, 359, 123209
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On-chip screening of SARS-CoV-2 cDNA by LAMP-integrated rotational diffusometry

Dhrubajyoti Das, Cheng-Wen Lin and Han-Sheng Chuang

Talanta, 2024, 267, 125253
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Fully integrated and automated centrifugal microfluidic chip for point-of-care multiplexed molecular diagnostics

Yujin Xiao, Mengfan Zhou, Changgen Liu, Siyu Gao, Chao Wan, Shunji Li, Chenxi Dai, Wei Du, Xiaojun Feng, Yiwei Li, Peng Chen and Bi-Feng Liu

Biosensors and Bioelectronics, 2024, 255, 116240
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Microfluidics-Based POCT for SARS-CoV-2 Diagnostics

Binfeng Yin, Xinhua Wan, A. S. M. Muhtasim Fuad Sohan and Xiaodong Lin

Micromachines, 2022, 13, 1238
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Progression of LAMP as a Result of the COVID-19 Pandemic: Is PCR Finally Rivaled?

Cassidy Mannier and Jeong-Yeol Yoon

Biosensors, 2022, 12, 492
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Quantitative or digital PCR? A comparative analysis for choosing the optimal one for biosensing applications

Haoqing Zhang, Lei Cao, Jan Brodsky, Imrich Gablech, Feng Xu, Zedong Li, Marie Korabecna and Pavel Neuzil

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Smartphone-driven centrifugal microfluidics for diagnostics in resource limited settings

Noa Lapins, Ahmad S. Akhtar, Indradumna Banerjee, Amin Kazemzadeh, Inês F. Pinto and Aman Russom

Biomed Microdevices, 2024, 26
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Microfluidic Integration of Magnetically Functionalized Microwires for Flow Cytometry Protein Quantification

Liviu Clime, Catalin Pavel, Lidija Malic, Christina Nassif, Matthias Geissler, Nicoleta Lupu, Tibor-Adrian Óvári, Lucas Poncelet, Gaétan Veilleux, Elham Moslemi, Javier Alejandro Hernández-Castro, Daniel Sinnett, Diping Che and Teodor Veres

Materials, 2025, 18, 215
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A Portable Dual-Mode Microfluidic Device Integrating RT-qPCR and RT-LAMP for Rapid Nucleic Acid Detection in Point-of-Care Testing

Baihui Zhang, Xiao Li, Mengjie Huang, Maojie Jiang, Leilei Du, Peng Yin, Xuan Fang, Xiangyu Jiang, Feihu Qi, Yanna Lin and Fuqiang Ma

Biosensors, 2026, 16, 51
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Development of a loop-mediated isothermal amplification (LAMP) assay for the detection of Cyclospora cayetanensis

Mahdid Meymandy, Nadine Adam, Nathalie Corneau and Brent R. Dixon

Food and Waterborne Parasitology, 2026, 43, e00337
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A Miniaturized System for Rapid, Isothermal Detection of SARS-CoV-2 in Human and Environmental Samples

Jake Staples, Athanasia-Maria Dourou, Irene Liampa, Calvin Sjaarda, Emily Moslinger, Henry Wong, Prameet M. Sheth, Stilianos Arhondakis and Ravi Prakash

Biomedicines, 2023, 11, 2038
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Quercetin-Mediated Silver Nanoparticle Formation for the Colorimetric Detection of Infectious Pathogens Coupled with Loop-Mediated Isothermal Amplification

Rajamanickam Sivakumar, So Yeon Park and Nae Yoon Lee

ACS Sens., 2023, 8, 1422
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A gamepad-like nucleic acid testing device for rapid detection of SARS-CoV-2 via visible nested recombinase polymerase amplification

Ce Liu, Baobao Lin, Guohua Yuan, Zhi Geng, Zhe Zhao, Jiacheng Wang, Jingyu Shao, Zhenqi Wang, Yang Xu, Xujuan Yang, Chang Liu, Yingmei Feng, Xin Fan, Jing Wang, Lili Ren, Yan Xiao, Conghui Wang, Guang Shen, Yi Yang, Chao Zhao, Yinqing Li, Peng Liu and Jingwei Bai

Commun Eng, 2024, 3
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Point-of-Care Devices for Viral Detection: COVID-19 Pandemic and Beyond

Sumit K. Yadav, Damini Verma, Ujala Yadav, Ashish Kalkal, Nivedita Priyadarshini, Ashutosh Kumar and Kuldeep Mahato

Micromachines, 2023, 14, 1744
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A machine learning and centrifugal microfluidics platform for bedside prediction of sepsis

Lidija Malic, Peter G. Y. Zhang, Pamela J. Plant, Liviu Clime, Christina Nassif, Dillon Da Fonte, Evan E. Haney, Byeong-Ui Moon, Victor Mun-Sing Sit, Daniel Brassard, Maxence Mounier, Eryn Churcher, James T. Tsoporis, Reza Falsafi, Manjeet Bains, Andrew Baker, Uriel Trahtemberg, Ljuboje Lukic, John C. Marshall, Matthias Geissler, Robert E. W. Hancock, Teodor Veres and Claudia C. dos Santos

Nat Commun, 2025, 16
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Development of a colorimetric RT-LAMP-based microfluidic device for SARS-CoV-2 detection

Tatsuya Sakurai, Hiroka Aonuma, Daigo Natsuhara, Tokio Hoshina, Manabu Ote, Erisha Saiki, Takayuki Shibata and Hirotaka Kanuka

Trop Med Health, 2026, 54
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Advances in Simple, Rapid, and Contamination-Free Instantaneous Nucleic Acid Devices for Pathogen Detection

Yue Wang, Chengming Wang, Zepeng Zhou, Jiajia Si, Song Li, Yezhan Zeng, Yan Deng and Zhu Chen

Biosensors, 2023, 13, 732
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Palm-shaped and one-step system (P-SOS) integrated with nucleic acid isothermal amplification to realize sample-to-results diagnosis of acute respiratory tract disease

Daoguangyao Zhang, Anyi Li, Jiandong Xu, Pei Ren, Liming Zhang, Xiangke Liu, Shiyong Yu and Yulin Deng

Microchemical Journal, 2025, 212, 113480
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