A coordinated framework for enhancing oxygen dynamics to improve the production of sesquiterpene

Yufei Bao, Yiying Huo, Haoran Bi, Lifeng Shi, Meng Wang, Mohamed Almarei, Rodrigo Ledesma-Amaro, Yunming Fang and Tianwei Tan

Green Chem., 2025, 27, 14374
DOI: 10.1039/D5GC04488J

Highly efficient biosynthesis of 2,4-dihydroxybutyric acid by a methanol assimilation pathway in engineered Escherichia coli

Xianjuan Dong, Chao Sun, Jing Guo, Xiangyu Ma, Mo Xian and Rubing Zhang

Green Chem., 2023, 25, 7662
DOI: 10.1039/D3GC02083E

Efficient production of citric acid from lignocellulose hydrolysate by metabolically engineered Yarrowia lipolytica

Minrui Lu, Yuanyuan Sha, Yuwei Zhang, Mianshen Ge, Zhaoxian Xu and Mingjie Jin

Green Chem., 2025, 27, 1113
DOI: 10.1039/D4GC05521G

Construction and optimization of efficient glucose–xylose co-fermenting yeast Yarrowia lipolytica for green and sustainable succinic acid production from lignocellulosic biomass

Mianshen Ge, Yuanyuan Sha, Minrui Lu, Yuwei Zhang, Zhaoxian Xu, Sitong Chen, Ying Ding and Mingjie Jin

Green Chem., 2025, 27, 450
DOI: 10.1039/D4GC04189E

Multidimensional metabolic engineering of Yarrowia lipolytica for highly efficient biosynthesis of betulinic acid

Xiaoyan Li, Liangcheng Jiao, Guowei Zhao, Yunchong Li, Yunjun Yan and Jinyong Yan

Green Chem., 2025, 27, 6855
DOI: 10.1039/D5GC01276G

From formate oxidation to CO₂ reduction: The role of formate dehydrogenase in sustainable carbon utilization

Yongmin Zheng, Chen Qi, Yangyi Qiao, Kang Liu, Yanxia Wang, Wankui Jiang, Yujia Jiang, Fengxue Xin, Feng Guo, Wenming Zhang and Min Jiang

Biotechnology Advances, 2025, 82, 108600
DOI: 10.1016/j.biotechadv.2025.108600

Engineering Escherichia coli to use formate and CO2 as carbon sources for the synthesis of succinic acid in a two-stage fermentation

Yao Liu, Xin Niu, Xin Zhang, Wenyao Song, Sheng Xu, Xin Wang, Jiao Feng and Kequan Chen

Chemical Engineering Journal, 2026, 539, 177153
DOI: 10.1016/j.cej.2026.177153

Upcycling C1 gas-derived resources in future food system

Jiawei Li, Jiunwei Tseng, Dan Tang, Yunqian Yong, Lichao Sun and Yi-Xin Huo

Resources, Conservation and Recycling, 2024, 210, 107827
DOI: 10.1016/j.resconrec.2024.107827

Advancing Succinic Acid Biomanufacturing Using the Nonconventional Yeast Yarrowia lipolytica

Tao Sun, Mei-Li Sun, Lu Lin, Jian Gao, Kaifeng Wang and Xiao-Jun Ji

J. Agric. Food Chem., 2025, 73, 100
DOI: 10.1021/acs.jafc.4c09990

Construction and applications of methanol bio-converting cell factories

Jiahao Wang, Guangjie Liang, Zixuan Wang, Cong Gao, Guipeng Hu, Liming Liu and Jing Wu

Biotechnology Advances, 2026, 87, 108805
DOI: 10.1016/j.biotechadv.2026.108805

Systems metabolic engineering of Corynebacterium glutamicum to assimilate formic acid for biomass accumulation and succinic acid production

Kai Li, Xue Zhang, Cheng Li, Yu-Cheng Liang, Xin-Qing Zhao, Chen-Guang Liu, Anthony J. Sinskey and Feng-Wu Bai

Bioresource Technology, 2024, 402, 130774
DOI: 10.1016/j.biortech.2024.130774

Advancing yeast metabolism for a sustainable single carbon bioeconomy

Miriam Kuzman, Özge Ata and Diethard Mattanovich

FEMS Yeast Research, 2025, 25
DOI: 10.1093/femsyr/foaf020

Yeast as C1 cell factory: Transforming methanol and Formate into high-value compounds

Ushasree Mrudulakumari Vasudevan, Laurence Soussan, Alfred Fernández-Castané, Stephan Noack and Alan D. Goddard

Biotechnology Advances, 2025, 83, 108641
DOI: 10.1016/j.biotechadv.2025.108641

Reprogramming Yarrowia lipolytica metabolism for efficient synthesis of itaconic acid from flask to semipilot scale

Jing Fu, Simone Zaghen, Hongzhong Lu, Oliver Konzock, Naghmeh Poorinmohammad, Alexander Kornberg, Rodrigo Ledesma-Amaro, Deni Koseto, Alexander Wentzel, Francesca Di Bartolomeo and Eduard J. Kerkhoven

Sci. Adv., 2024, 10
DOI: 10.1126/sciadv.adn0414

Komagataella phaffii: A versatile platform for the production of value-added chemicals

Qiang Zhou, Jiahui Yang, Wenming Zhang, Wankui Jiang, Jianxiang Chen, Lei Chen, Yujia Jiang and Fengxue Xin

Green Carbon, 2025, 3, 407
DOI: 10.1016/j.greenca.2025.01.004

Evaluating the toxicity of methanol, formaldehyde and formate on the growth fitness of Yarrowia lipolytica

Wei Kuang, Yuxiang Hong, Zimu Hu and Peng Xu

Results in Engineering, 2025, 26, 105016
DOI: 10.1016/j.rineng.2025.105016

Advances in microbial bioconversion of methanol

Peng Cai, Xiaoyan Wu, Linfeng Xie, Yiwei Shen, Linhui Gao and Yongjin Zhou

Sci. Sin.-Chim, 2024, 54, 2199
DOI: 10.1360/SSC-2024-0161

Understanding methanol metabolism through systems biology: advances and future perspectives

Haoyu Wang, Fan Bai, Hongzhong Lu and Yongjin J Zhou

Current Opinion in Biotechnology, 2025, 96, 103370
DOI: 10.1016/j.copbio.2025.103370

Engineering Methylotrophic Yeasts as Cell Factories for Chemical Production Using Methanol as a Feedstock

Shuxian Wang, Jiayu Fang, Yanping Zhang, Yin Li and Taicheng Zhu

GCB Bioenergy, 2025, 17
DOI: 10.1111/gcbb.70068

Carbon efficient production of chemicals with yeasts

Evelyn Vásquez Castro, Golnaz Memari, Özge Ata and Diethard Mattanovich

Yeast, 2023, 40, 583
DOI: 10.1002/yea.3909

Evolutionary engineering of Saccharomyces cerevisiae : Crafting a synthetic methylotroph via self-reprogramming

Feng Guo, Kang Liu, Yangyi Qiao, YongMin Zheng, Chenguang Liu, Yi Wu, Zhonghai Zhang, Wankui Jiang, Yujia Jiang, Fengxue Xin, Min Jiang and Wenming Zhang

Sci. Adv., 2024, 10
DOI: 10.1126/sciadv.adq3484

Multi-Omics Analysis Reveals 1-Propanol-Induced Pentadecanoic Acid Biosynthesis in Yarrowia lipolytica

Jiahe Cong, Xin Hu, Dongsheng Lu, Sam C. Kollie, Ahmed A. Elolimy, Juan J. Loor, Zhendong Yang, Mingxun Li, Yongjiang Mao, Zhangping Yang and Huimin Zhang

Biomolecules, 2025, 15, 1618
DOI: 10.3390/biom15111618

Harnessing yeasts for sustainable succinic acid production: advances in metabolic engineering and biorefinery integration

Vasiliki Korka, Apostolos Petropoulos, Sofia Maria Ioannidou, Carol Sze Ki Lin, Apostolis Koutinas and Patrick Fickers

FEMS Yeast Research, 2025, 25
DOI: 10.1093/femsyr/foaf052

De Novo Biosynthesis of Lutein in Yarrowia lipolytica

Zhilei Qin, Mengsu Liu, Xuefeng Ren, Weizhu Zeng, Zhengshan Luo and Jingwen Zhou

J. Agric. Food Chem., 2024, 72, 5348
DOI: 10.1021/acs.jafc.3c09080

Recent developments of oleaginous yeasts toward sustainable biomanufacturing

Paul A Adamczyk, Tian Jiang, Karuna Jetty, Vijaydev Ganesan and Di Liu

Current Opinion in Biotechnology, 2025, 93, 103297
DOI: 10.1016/j.copbio.2025.103297

Hybrid Methylotrophic Pathway in Serratia marcescens for Sustainable Terpenoid Biosynthesis

Di Liu, Long Wang, Linbo Gou, Yao Lu, Yongai Ma, Songsong Yao, Tai-Ping Fan, Huaxiang Deng and Yujie Cai

ACS Synth. Biol., 2025, 14, 1766
DOI: 10.1021/acssynbio.5c00116

Compartment engineering in yeast: a path to increased biochemical production

Yuyang Wang, Liyan Cao, Lanxin Rong, Chen Ding, Chang Liu, Qingqing Ye, Qingeng Huang, Cui-ying Zhang, Ning Xu, Jiwei Mao, Jee Loon Foo and Aiqun Yu

Chemical Engineering Journal, 2025, 524, 169279
DOI: 10.1016/j.cej.2025.169279

Progresses of engineering microbial chassis for one-carbon biotransformation

Yiwei Shen, Peng Cai and Yongjin Zhou

Chin. Sci. Bull., 2026, 71, 4165
DOI: 10.1360/TB-2025-0119

Engineering the robustness of Meyerozyma guilliermondii for efficient 2-phenylethanol biosynthesis

Feng Guo, Wenqi Ma, Zijian Wan, Yujia Jiang, Wankui Jiang, Fengxue Xin, Wenming Zhang and Min Jiang

Metabolic Engineering, 2026, 96, 193
DOI: 10.1016/j.ymben.2026.03.016

De Novo Biosynthesis of Sakuranetin in Yarrowia lipolytica Through Systemic Metabolic Engineering

Jiayun Xu, Wenping Wei, Gaopan Cai, Mengfan Li, Tao Qian, Xiaohe Chu and Bang‐Ce Ye

Biotech and App Biochem, 2026, 73, 1102
DOI: 10.1002/bab.70082

Non-agricultural feedstocks for next-generation biomanufacturing with yeasts

Simone Bachleitner, Anna M Erian, Diethard Mattanovich and Özge Ata

Current Opinion in Biotechnology, 2026, 99, 103509
DOI: 10.1016/j.copbio.2026.103509

Perspectives for Advancing Biotechnological Succinic Acid Production

Christoph Gunkel and Bastian Blombach

Microbial Biotechnology, 2026, 19
DOI: 10.1111/1751-7915.70363

Microbial engineering for sustainable biomanufacturing of succinate

Deyang Ding, Yongsheng Tang, Zhe Zhang, Fanglong Zhao and Xiulai Chen

Food Bioscience, 2026, 81, 109242
DOI: 10.1016/j.fbio.2026.109242

Organic Acid Production by Yeast Yarrowia lipolytica: A Review of the Last Five Years of Research

Svetlana V. Kamzolova

Fermentation, 2025, 11, 646
DOI: 10.3390/fermentation11110646

Harnessing yeasts for sustainable methanol valorization: Metabolic and fermentation engineering strategies

Yujung Choi, Yejee Park, Yejin Lin, Hyunjun Min, Daeun Lee, Jiwoo Kwon, Seunghyun Kim, Jeong Chan Joo and Nam Kyu Kang

New Biotechnology, 2026, 94, 106
DOI: 10.1016/j.nbt.2026.05.011

Methylotrophic yeasts for chemicals production using methanol as substrate: Current status, challenges, and strategies

Xiyu Duan, Chong Wang, Xiaona Yang, Huhu Liu, Xiangyang Lu, Changzhu Li, Peiwang Li, Zhi Wang and Yun Tian

Bioresource Technology, 2025, 434, 132815
DOI: 10.1016/j.biortech.2025.132815

Formaldehyde: An Essential Intermediate for C1 Metabolism and Bioconversion

Mengshi Jia, Mengge Liu, Jiawen Li, Wankui Jiang, Fengxue Xin, Wenming Zhang, Yujia Jiang and Min Jiang

ACS Synth. Biol., 2024, 13, 3507
DOI: 10.1021/acssynbio.4c00454