Identification of α-tubulin alpha-1B chain as a target of asiatic acid using chemical proteomics in HepG2 hepatoma cells

Hong Yang, Bingbing Yang, Yu Teng, Jun Ge, Xinchi Feng and Yulin Tian

Org. Biomol. Chem., 2024, 22, 9371
DOI: 10.1039/D4OB01298D

Phenylethanol Glycosides from Cistanche tubulosa Modulate the Gut Microbiota and Cecal Metabolites to Ameliorate Diabetic Nephropathy Induced by Streptozotocin Combined with High-Fat Diet in Rats

Chong Ma, Bowei Ju, Jiangyun Liu, Limei Wen, Yao Zhao, Jianhua Yang and Junping Hu

Journal of Medicinal Food, 2025, 28, 219
DOI: 10.1089/jmf.2024.k.0175

Characterisation and In Vitro Drug Release Profiles of Oleanolic Acid- and Asiatic Acid-Loaded Solid Lipid Nanoparticles (SLNs) for Oral Administration

Michael Oboh, Eman Elhassan, Neil Anthony Koorbanally, Laurencia Govender, Muthulisi Siwela, Thirumala Govender and Blessing Nkazimulo Mkhwanazi

Pharmaceutics, 2025, 17, 723
DOI: 10.3390/pharmaceutics17060723

Resistant starch prepared from taro using high-pressure sterilization and enzymatic hydrolysis: Structural characteristics and its alleviating effect on DSS-induced colitis

Xiaotong Chen, Weixiao Dong, Peiyao Guan, Juan Kan, Chao Tang, Jun Liu and Changhai Jin

Food Bioscience, 2025, 71, 107235
DOI: 10.1016/j.fbio.2025.107235

Selective impact of three homogenous polysaccharides with different structural characteristics from Grifola frondosa on human gut microbial composition and the structure-activity relationship

Guangjian Bai, Yizhen Xie, Xiong Gao, Chun Xiao, Tianqiao Yong, Longhua Huang, Manjun Cai, Yuanchao Liu, Huiping Hu and Shaodan Chen

International Journal of Biological Macromolecules, 2024, 269, 132143
DOI: 10.1016/j.ijbiomac.2024.132143

The regulatory effects of specific polyphenols on Akkermansia are dependent on uridine

Xiaoxiang Gao, Chenbo Yue, Ruocen Tian, Leilei Yu, Fengwei Tian, Jianxin Zhao, Wei Chen and Qixiao Zhai

Food Chemistry, 2023, 410, 135367
DOI: 10.1016/j.foodchem.2022.135367

Peritoneal dialysis promotes microbial-driven biosynthesis pathways of sesquiterpenes and triterpenes compounds in end-stage renal disease patients

Xinran Wang, Siqi Yao, Xinyu Yang, Yuxin Li, Zheng Yu, Jing Huang and Jianwen Wang

BMC Microbiol, 2024, 24
DOI: 10.1186/s12866-024-03539-3

Finger Citron (Citrus medica L. var. sarcodactylis Swingle) and Its Characteristic Component Limettin Alleviated Diet-Induced Obesity via Modulating Gut Microbiota and Steroid Hormone Biosynthesis

Jiebiao Chen, Xinyu Shen, Yunyi Chen, Jiaojiao Liang, Yan Liu, Jinping Cao, Li-Shu Wang, Baiyi Lu, Chongde Sun and Yue Wang

J. Agric. Food Chem., 2026, 74, 10232
DOI: 10.1021/acs.jafc.5c15347

Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis Residue Alleviate Liver Injury in D-Galactose-induced Aging Mice through Gut-liver Axis

Yuling Zhang, Chunhao Gao, Mengjia Zhu, Fangtian Chen, Yongye Sun, Yu Jiang, Qingxin Zhou and Xiang Gao

J. Oleo Sci., 2024, 73, 729
DOI: 10.5650/jos.ess24003

Asiatic acid inhibits cervical cancer cell proliferation and migration via PI3K/AKT/mTOR signaling pathway

Xiuying Lin, Yanqiu Fang, Xuguang Mi, jianhua Fu, Shiling Chen, Mengxue Wu and Ningyi Jin

Heliyon, 2024, 10, e34047
DOI: 10.1016/j.heliyon.2024.e34047

A Mix of Probiotic Strains Prevents Hepatic Steatosis, and Improves Oxidative Stress Status and Gut Microbiota Composition in Obese Mice

Chenglin Guo, Shengduo He, Mélanie Le Barz, Sylvie Binda and Huahong Wang

Molecular Nutrition Food Res, 2024, 68
DOI: 10.1002/mnfr.202300672

Efficacy of DHA-enriched phosphatidylserine and its underlying mechanism in alleviating polystyrene nanoplastics-induced hepatotoxicity in mice

Yuanlei Zhang, Qiaoling Zhao, Rui Zhao, Yun Lu, Su Jiang and Yunping Tang

International Immunopharmacology, 2024, 142, 113154
DOI: 10.1016/j.intimp.2024.113154

Effects of Kadsura coccinea L. Fruit Extract on Growth Performance, Meat Quality, Immunity, Antioxidant, Intestinal Morphology and Flora of White-Feathered Broilers

Tianlu Zhang, Dong Zhou, Xin Wang, Tian Xiao, Lingxi Wu, Qi Tang and Ying Lu

Animals, 2022, 13, 93
DOI: 10.3390/ani13010093

5‐Fluorouracil Loaded Prebiotic–Probiotic Liposomes Modulating Gut Microbiota for Improving Colorectal Cancer Chemotherapy

Xujie Sun, Xiaoting Shan, Binyu Zhu, Ying Cai, Zongyan He, Lingli Zhou, Lixuan Yin, Yiran Liu, Kaiyue Liu, Tian Zhang, Ning Yang, Yaping Li and Tianqun Lang

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202403587

Targeting Renal Proximal Tubule Cells in Obesity-Related Glomerulopathy

Muyao Ye, Ming Yang, Wenni Dai, Hao Li, Xun Zhou, Yinyin Chen and Liyu He

Pharmaceuticals, 2023, 16, 1256
DOI: 10.3390/ph16091256

Comparison of the Effects between Tannins Extracted from Different Natural Plants on Growth Performance, Antioxidant Capacity, Immunity, and Intestinal Flora of Broiler Chickens

Song Liu, Kaijun Wang, Senzhu Lin, Zhidan Zhang, Ming Cheng, Shanshan Hu, Hongjie Hu, Jun Xiang, Fengming Chen, Gonghe Li and Hongbin Si

Antioxidants, 2023, 12, 441
DOI: 10.3390/antiox12020441

Effects of fermented Arctium lappa L. root by Lactobacillus casei on hyperlipidemic mice

MingJu Chen, Yuxiao Wu, Hongxuan Yang, Tianfeng Liu, Tongkun Han, Wangqiang Dai, Junyue Cen, Fan Ouyang, Jingjing Chen, Jianxin Liu, Lin Zhou and Xuguang Hu

Front. Pharmacol., 2024, 15
DOI: 10.3389/fphar.2024.1447077

Fucoidan dose-dependently alleviated hyperuricemia and modulated gut microbiota in mice

Yan-Xin Wang, Xiao-Long Chen, Kai Zhou, Lu-Lu Wang, Yu-Zhen Zhong, Jie Peng, Bao-Sheng Ge, Chi-Tang Ho and Chen-Yang Lu

Food & Medicine Homology, 2025
DOI: 10.26599/FMH.2026.9420095

Fatty acid metabolism in gouty arthritis: mechanisms to therapeutic targeting

Xueping Zhao, Ye Sun, Le Yang, Hui Sun, Xinya Zhang, Hui Sun, Guangli Yan and Xijun Wang

Front. Immunol., 2025, 16
DOI: 10.3389/fimmu.2025.1671548

Terpenoids in the management of MASLD: Multi-target mechanisms, therapeutic potential, and future perspectives

Chengzi Huang, Rong Zhang, Caizhi Liu and Cheng Hu

Pharmacological Research, 2026, 228, 108231
DOI: 10.1016/j.phrs.2026.108231

Biotransformation of asiatic acid by Cunninghamella echinulata and Circinella muscae to discover anti-neuroinflammatory derivatives

Yanni Wu, Youjia Lu, Ying Yi, Andong Wang, Wenli Wang, Min Yang, Boyi Fan and Guangtong Chen

Natural Product Research, 2023, 37, 2712
DOI: 10.1080/14786419.2022.2132500

Silibinin Targeting Heat Shock Protein 90 Represents a Novel Approach to Alleviate Nonalcoholic Fatty Liver Disease by Simultaneously Lowering Hepatic Lipotoxicity and Enhancing Gut Barrier Function

Baofei Yan, Xian Zheng, Xi Chen, Huihui Hao, Shen Shen, Jingwen Yang, Siting Wang, Yuping Sun, Jiaqi Xian, Zhitao Shao and Tingming Fu

ACS Pharmacol. Transl. Sci., 2024, 7, 2110
DOI: 10.1021/acsptsci.4c00185

10-hydroxy-2-decenoic acid alleviates lipopolysaccharide-induced intestinal mucosal injury through anti-inflammatory, antioxidant, and gut microbiota modulation activities in chickens

Lianquan Han, Maolu Zhang, Fuwei Li, Jing Su, Ruiming Wang, Guiming Li and Xiaohui Yang

Front. Microbiol., 2023, 14
DOI: 10.3389/fmicb.2023.1285299

Cytidine Alleviates Dyslipidemia and Modulates the Gut Microbiota Composition in ob/ob Mice

Kaixia Niu, Pengpeng Bai, Junyang Zhang, Xinchi Feng and Feng Qiu

Nutrients, 2023, 15, 1147
DOI: 10.3390/nu15051147

Molecular Mechanisms Underlying the Effects of Small Intestinal Fermentation on Enhancement of Prebiotic Characteristics of Cellulose in the Large Intestine

Yu Bai, Yiming Zhang, Chen Chao, Jinglin Yu, Jinbiao Zhao, Dandan Han, Junjun Wang and Shujun Wang

J. Agric. Food Chem., 2024, 72, 3596
DOI: 10.1021/acs.jafc.3c09146