Enhanced ROS generation in AIE-active iridium(iii) photosensitizers by cationization engineering for advanced photodynamic therapy

Shanshan Huang, Yuancheng Li, Xiaohan Xie, Jialin Tong, Guo-Gang Shan, Chao Qin, Xiyan Xiao, Qianruo Wang, Yuanyuan Li and Hualei Wang

Inorg. Chem. Front., 2025, 12, 986
DOI: 10.1039/D4QI02477J

Long-wavelength triggered iridium(iii) complex nanoparticles for photodynamic therapy against hypoxic cancer

Shengnan Liu, Ziwei Wang, Zihan Wu, Haoran Chen, Dongxia Zhu, Gungzhe Li, Mingming Yan, Martin R. Bryce and Yulei Chang

Chem. Commun., 2024, 60, 9938
DOI: 10.1039/D4CC03501A

Near-infrared AIE-active phosphorescent iridium(iii) complex for mitochondria-targeted photodynamic therapy

Zheng-Yin Pan, Bin-Fa Liang, Yun-Shi Zhi, Da-Hong Yao, Chen-Yang Li, Hai-Qiang Wu and Liang He

Dalton Trans., 2023, 52, 1291
DOI: 10.1039/D2DT03861G

Aggregation-induced emission of cyclometalated rhodium(iii) and iridium(iii) phenylpyridine complexes with ancillary 1,3-diketones

Marina A. Kiseleva, Andrei V. Churakov, Ilya V. Taydakov, Mikhail T. Metlin, Sergey A. Kozyukhin and Stanislav I. Bezzubov

Dalton Trans., 2023, 52, 17861
DOI: 10.1039/D3DT02651E

Anticancer profile of coumarin 6-based Ir(iii) photocatalysts under normoxia and hypoxia by ROS generation and NADH oxidation

Ashish Kumar Yadav, Aarti Upadhyay, Arpan Bera, Rajesh Kushwaha, Arif Ali Mandal, Sagar Acharjee, Amit Kunwar and Samya Banerjee

Inorg. Chem. Front., 2024, 11, 5435
DOI: 10.1039/D4QI01601G

Luminescent array sensors for pathogen identification using AIE-active cationic iridium complexes

Sonali Bera, Aryan Gautam, Gaurank Pal and Puja Prasad

Chem. Commun., 2026, 62, 2212
DOI: 10.1039/D5CC05604G

Dual RONS-responsive chemiluminescence-guided multimodal thrombolysis based on an aggregation-induced emission cobalt-porphyrin nanoplatform

Ziwei Wang, Liping Zhang, Zihan Wu, Kaijia Lin, Yachao Wang, Gelin Xu, Feng Chi, Weijin Zhu, Qianwen Liu, Dongxia Zhu, Martin R. Bryce, Ben Zhong Tang and Lijie Ren

Chem. Sci., 2026
DOI: 10.1039/D6SC02507B

Cationic iridium(iii) complexes with a halogen-substituted pyridylbenzimidazole ancillary ligand for photodynamic therapy

Pierre-Henri Lanoë, Frédérique Loiseau, Christian Philouze, Camille Latouche, Laetitia Vanwonterghem, Louis Biancon, Ahmed S. Faihan, Florian Molton, Matéo Lavaud, Anne-Laure Bulin, Jean-Luc Coll, Akos Banyasz and Amandine Hurbin

Mater. Adv., 2025, 6, 8034
DOI: 10.1039/D5MA00964B

Imidazolium-tethered red-emissive iridium AIEgen for sensitive detection of NAD(P)H in aqueous and cellular media

Aryan Gautam, Ajay Gupta, Deepika Chauhan, Amit Kunwar and Pijus K. Sasmal

J. Mater. Chem. B, 2026, 14, 2866
DOI: 10.1039/D5TB02044A

Spectroscopic, structural and photophysical characterization of chloro-bridged iridium(iii) and rhodium(iii) dinuclear complexes with 1-phenyl-1H-pyrazole and their analogues with 1-(2,4-difluorophenyl)-1H-pyrazole

Patryk Wójcik, Camille Latouche, Kinga Suwińska and Anna Kamecka

Dalton Trans., 2025, 54, 12018
DOI: 10.1039/D5DT01156F

Exploring the singlet oxygen generation of iridium(III) complex containing phenothiazine for photodynamic therapy

Qinglin Chen, Hong Zeng, Jie Wu, Yuanyan Li, Yibao Li and Yongquan Wu

Journal of Inorganic Biochemistry, 2026, 275, 113149
DOI: 10.1016/j.jinorgbio.2025.113149

Acceptor Elongation Boosted Intersystem Crossing Affords Efficient NIR Type‐I and AIE‐Active Photosensitizers for Targeting Ferroptosis‐Based Cancer Therapy

Yilin Zhu, Rongyuan Zhang, Xu‐Min Cai, Liping Zhang, Bo Wu, Haozhe Tan, Kun Zhou, Haoran Wang, Yong Liu, Yumei Luo, Ryan T. K. Kwok, Jacky W. Y. Lam, Zheng Zhao, Cuiping Yao and Ben Zhong Tang

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202404505

Preparation of magnetic cationic Schiff base polymeric material for highly selective enrichment of avermectins from surface water and milk samples

Can Zhang, Pingping Zhang, Wenyuan Zhu, Shuo Li, Yue Gu, Jing Wu, Di Wen, Weili Hao, Ke Wang, Ling Ma and Kaoqi Lian

Journal of Chromatography A, 2024, 1731, 465169
DOI: 10.1016/j.chroma.2024.465169

Cyclometalated Iridium(III) Complexes with Optimally Allocated Excited-State Energy for Near-Infrared Photodynamic and Photothermal Therapy

Yun Li, Xiao-Qi Zheng, Ding Wang, Chun-Lai Wei, Ya-Man Huang, Meng-Chi Han, Ze-Ming Wang, Xue-Lian Li, Qing-Fang Li, Zhongyan Cai, Xiaoxia Ren and Feng Gao

Inorg. Chem., 2025, 64, 19044
DOI: 10.1021/acs.inorgchem.5c03265

Rational Molecular Designing of Aggregation-Enhanced Emission (AEE) Active Red-Emitting Iridium(III) Complexes: Effect of Lipophilicity and Nanoparticle Encapsulation on Photodynamic Therapy Efficacy

Sumit, Kavya Sree Maravajjala, Simran Khanna, Vishal Kachwal, Karnam Laxmi Swetha, Santosh Manabala, Rajdeep Chowdhury, Aniruddha Roy and Inamur Rahaman Laskar

ACS Appl. Bio Mater., 2023, 6, 1445
DOI: 10.1021/acsabm.2c00998

Schiff Bases: A Short Survey on a Promising Scaffold in Drug Discovery

Alessia Catalano

CMC, 2023, 30, 4176
DOI: 10.2174/0929867330666230201121432

Photodynamic antimicrobial activity against S. aureus of metallic Iridium(III) complexes with Helicin pendant

Beibei Shi, Yu Huang, Jing Zhao, Yanshi Xiong, Xiangwen Liao and Jintao Wang

Journal of Organometallic Chemistry, 2024, 1008, 123044
DOI: 10.1016/j.jorganchem.2024.123044

Recent Advances in Photosensitizer Materials for Light‐Mediated Tumor Therapy

Minle Chen, Qianru Zhu, Zhenzhen Zhang, Qiushui Chen and Huanghao Yang

Chemistry An Asian Journal, 2024, 19
DOI: 10.1002/asia.202400268

Cationic cyclometalated platinum (II) complexes of metformin with self-assembly and AIE behavior as nuclear and mitochondrial targeted anticancer theragnostic agents

Da-Lei Chen, Wen-Ting Wang, Peng-Min Shi, Bo Yang, Xia-Li Liao, Chuan-Zhu Gao and Jing Yang

Dyes and Pigments, 2024, 223, 111971
DOI: 10.1016/j.dyepig.2024.111971

An iridium‐based phosphorescence probe for HClO/ClO− detection and application of recognizing exogenous/endogenous HClO/ClO− in cells

Sha Xu, Qikai Ju, Zhijian Li, Xueting Mao, Shuaihua Chen, Shouzhi Pu and Daobin Zhang

Applied Organom Chemis, 2024, 38
DOI: 10.1002/aoc.7478

Self-Chemiluminescence-Triggered Ir(III) Complex Photosensitizer for Photodynamic Therapy against Hypoxic Tumor

Shengnan Liu, Haoran Chen, Qi Wu, Yan Sun, Yu Pei, Ziwei Wang, Dongxia Zhu, Gungzhe Li, Martin R. Bryce and Yulei Chang

Inorg. Chem., 2024, 63, 16404
DOI: 10.1021/acs.inorgchem.4c02399

Iridium(III)-Based Infrared Two-Photon Photosensitizers: Systematic Regulation of Their Photodynamic Therapy Efficacy

Xue-Lian Li, Li-Zhen Zeng, Rong Yang, Xu-Dan Bi, Yang Zhang, Ruo-Bing Cui, Xin-Xi Wu and Feng Gao

Inorg. Chem., 2023, 62, 16122
DOI: 10.1021/acs.inorgchem.3c02364

The Role of Rigidity in Augmentation of Fluorescence and Room-Temperature Phosphorescence in Multinuclear Zn2+-Schiff Base Complexes

Arkaprava Chowdhury, Souradip Dasgupta, Mirza Nasib Begg, Nrita Gaur, Dinesh Kabra and Anindya Datta

J. Phys. Chem. Lett., 2025, 16, 10449
DOI: 10.1021/acs.jpclett.5c02185

Supramolecular clumps of μ2-1,3-acetate bridges of Cd(II)-Salen complex: Synthesis, spectroscopic characterization, crystal structure, DFT quantization's, and antifungal photodynamic therapy

Dhrubajyoti Majumdar, Jessica Elizabeth Philip, Bouzid Gassoumi, Sahbi Ayachi, Balkis Abdelaziz, Burak Tüzün and Sourav Roy

Heliyon, 2024, 10, e29856
DOI: 10.1016/j.heliyon.2024.e29856

Constructing 1 + 1 > 2 Photosensitizers Based on NIR Cyanine–Iridium(III) Complexes for Enhanced Photodynamic Cancer Therapy

Ziwei Wang, Weijin Wang, Qi Wu and Dongxia Zhu

Molecules, 2025, 30, 2662
DOI: 10.3390/molecules30122662

Self-Immolative Cationic Iridium(III) Complex-Encapsulated Nanoprodrug for Enhanced Chemo-Photodynamic Synergistic Therapy of Melanomas

Chaolong Liu, Jianqin Yan, Miaomiao Wu, Wenyu Wang, Lu Yuan, Dihua Tian, Yong Sun and Run Zhang

J. Am. Chem. Soc., 2025, 147, 27812
DOI: 10.1021/jacs.5c06657

Micelle encapsulated luminescent iridium(III)(ppy)2L complexes: Photophysics, photocytotoxic activity in HeLa cells and morphological confocal microscopy imaging in C. flavicans M. larva and L. sativum L. plant

Aleksandra Kowalczyk, Rafał Karpowicz, Łukasz Szczupak, Magdalena Gapińska, Aleksander Gorski, Natalia Dutkiewicz, Roger J. Kutta and Konrad Kowalski

Journal of Organometallic Chemistry, 2024, 1006, 123017
DOI: 10.1016/j.jorganchem.2024.123017

Cyclometalated Ir(III) Complexes as Lysosome-Targeted Photodynamic Anticancer Agents

Jiayi Zhu, Yan Liu, Zhao Zhang, Xili Yang and Feng Qiu

ACS Omega, 2023, 8, 34557
DOI: 10.1021/acsomega.3c03234

Dinuclear Dicationic Iridium Complexes for Highly Synergistic Photodynamic and Photothermal Therapy to Chemoresistant Cancer

Li-Zhen Zeng, Xue-Lian Li, Yu-Ang Deng, Run-Yu Zhao, Ran Song, Yu-Fei Yan, Meng-Fan Wang, Xiang-Han Wang, Xiaoxia Ren and Feng Gao

Inorg. Chem., 2025, 64, 967
DOI: 10.1021/acs.inorgchem.4c04282

Anticancer potential of polypyridyl-based Ir(III)-coumarin 6 conjugates under visible light and dark

Ashish Kumar Yadav, Virendra Singh, Rajesh Kushwaha, Amit Kunwar, Biplob Koch and Samya Banerjee

Inorganic Chemistry Communications, 2025, 175, 114184
DOI: 10.1016/j.inoche.2025.114184