A selenide-based coumarin fluorescent probe for fluorescence imaging of hypochlorous acid in cells and zebrafish

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Advances in electrospun nanofibrous membrane sensors for ion detection

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Lysosome-targeting luminescent lanthanide complexes: from molecular design to bioimaging

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A ratiometric nanoprobe for the in vivo bioimaging of hypochlorous acid to detect drug-damaged liver and kidneys

Lina Shangguan, Xiaoli Qian, Zhuoyang Wu, Tingting Han, Wanlu Sun, Li Liu and Yi Liu

Analyst, 2023, 148, 762
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Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy

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Development of an ultrafast fluorescent probe for specific recognition of hypochlorous acid and its application in live cells

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N-doped carbon dots as robust fluorescent probes for the rapid detection of hypochlorite

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One-step synthesis of a dual-functional AIE-active probe for ClO− detection and photodynamic therapy

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Chem. Commun., 2024, 60, 984
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Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

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HClO imaging in vivo and drug-damaged liver tissues by a large Stokes shift fluorescent probe

Xiangbao Liu, Chuan He, Qi Li, Zhongtao Li, Likun Liu, Song Chen and Peng Hou

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 302, 123081
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A robust dual-channel fluorescence-enhanced probe for duplex imaging of endogenous HClO/ClO- in living cells and in zebrafish

Peng Hou, Guofang Li, Zeqiang Li, Liling Yue, Likun Liu, Jingwen Sun, Haijun Wang, Wenqiang Chen, Xiangzhi Song and Song Chen

Sensors and Actuators B: Chemical, 2022, 359, 131562
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Pyrene‐diaminomaleonitrile‐based fluorescent probe for the turn‐on detection and bioimaging of hypochlorite

Bingbing Yue, Ruida Shi, Huiwen Yang, Caifeng Ding, Haitao Yu and Yanyu Qi

Responsive Materials, 2025, 3
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Recent progress and developments on phenothiazine-based fluorescence probe for hypochlorous acid sensing

Pranjal Gulati, Shilpa Taneja and Selva Kumar Ramasamy

Journal of Molecular Structure, 2026, 1349, 143837
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Dual-channel fluorescent probe for monitoring the dynamic changes of hypochlorite ion and ATP in drug-induced liver injury

Pan-Dong Mao, Shuang-Shuang Liu, Ze-Yi Lian, Wei-Na Wu, Lin-Yan Bian, Yuan Wang, Zhi-Hong Xu and Tony D. James

Sensors and Actuators B: Chemical, 2025, 440, 137908
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A new and fast-response two-photon fluorescent probe based on (p-Nitrophenylsulfonyl) hydrazine for detecting endogenous HClO and its application in zebrafish imaging

Cong-Cong Li, Dejun Dong, Jianbo Qu, Zhanping Yang and Jian-Yong Wang

Journal of Photochemistry and Photobiology A: Chemistry, 2023, 434, 114204
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A ratiometric fluorescent probe for rapid and specific detection of hypochlorite

Pu Chen, Qingli Nie, Yuting Yan, Juncheng Yang, Hai‐Tao Feng and Ben Zhong Tang

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N-Alkylation of 2-methoxy-10H-phenothiazine revisited. A facile entry to diversely N-substituted phenothiazine-coumarin hybrid dyes

Valentin Quesneau, Kévin Renault, Myriam Laly, Sébastien Jenni, Flavien Ponsot and Anthony Romieu

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Natural harmaline acts as novel fluorescent probe for hypochlorous acid and promising therapeutic candidate for rheumatoid arthritis

Dongbin Zheng, Yi Zuo, Longxuan Li, Arlene McDowell, Yuening Cao, Xiaoping Ye, Houcheng Zhou, Cheng Peng, Yun Deng, Jun Lu and Yuyu Fang

Journal of Photochemistry and Photobiology B: Biology, 2024, 258, 112995
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Two-Photon Cellular and Intravital Imaging of Hypochlorous Acid by Fluorescent Probes That Exhibit a Synergistic Excited-State Intramolecular Proton Transfer–Intramolecular Charge Transfer Mechanism Enabling Near-Infrared Emission with a Large Stokes Shift

Ying Long, Junru Liu, Zhenghua Ju, Fujian Qi, Wei Tang, Shuai Yan, Fang Dai, Shengxiang Zhang and Bo Zhou

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Dicyanoisophorone-Based Fluorescent Probe with Large Stokes Shift for Ratiometric Detection and Imaging of Exogenous/Endogenous Hypochlorite in Cell and Zebrafish

Xiangyu Kong, Shaomin Shuang, Yuetao Zhang, Yu Wang and Chuan Dong

SSRN Journal, 2021
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Rapid on-site detection of hypochlorite: A novel phenothiazine-based fluorescent probe for environmental water monitoring and paper-based sensing

Pranjal Gulati, Shilpa Taneja, Pravinkumar Selvam, Selva Kumar Ramasamy and S.K. Ashok Kumar

Journal of Molecular Structure, 2026, 1369, 146332
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An HOCl-activated chemiluminescent prodrug enabling self-reporting camptothecin release and imaging-guided therapy in peritoneal metastasis

Yanhan Zhou, Hongchao Wang, Maocheng Yang, Hongyu Li, Zeli Yuan and Jie Gao

Bioorganic & Medicinal Chemistry, 2026, 140, 118717
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Detecting mitochondrial hypochlorous acid and viscosity in atherosclerosis models via NIR fluorescent probes

Quanli Cheng, Jian Sun, Baoguo Wang, Aixiang Ding, Wan Sun, Fan Yang and Jian Zhang

Bioorganic Chemistry, 2025, 156, 108191
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A novel viscosity/HClO dual-responsive fluorescent probe with mitochondrial localization ability and bio-imaging

Ting Yu, Huiting Li, Zhenming Dong, Lele Yan, Xiaoqing Yan, Yu Wang and Shaomin Shuang

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A novel diaminomaleonitrile-based fluorescent probe for the fast detection of hypochlorite in water samples and foods

Wenhui Xia, Yuehua Yuan, Siyi Shen, Yongjun Zhu, Yuzhen Wang, Ying Hou, Baimei Huang, Maozhong Tian and Feng Feng

Journal of Food Composition and Analysis, 2024, 128, 106053
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Fluorescent Probes for Selective Recognition of Hypobromous Acid: Achievements and Future Perspectives

Yuyu Fang and Wim Dehaen

Molecules, 2021, 26, 363
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Novel NIR fluorescent probe for hypochlorite ion detection in biological systems

Jian Zhang, Yu Nan and Hushan Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 308, 123717
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A lysosome-targeted fluorescent probe for fluorescence imaging of hypochlorous acid in living cells and in vivo

Ke An, Jiaxin Fan, Bin Lin and Yifeng Han

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 316, 124316
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Development of a novel highly specific fluorescent probe for detecting HOCl in living cells and zebrafish, as well as real water samples

Mingshuo Ma, Jie Chen, Shihua Yu, Zhigang Liu and Xiaodan Zeng

Journal of Molecular Structure, 2022, 1268, 133744
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A Dual Functional Fluorescent Probe Based on Phenothiazine for Detecting Hg2+ and ClO− and its Applications

Cheng-lu Zhang, Chang Liu, Shi-ru Nie, Yang Zhang, Jing-hao Guo, Xiang-ling Li and Cui Liu

J Fluoresc, 2023, 35, 397
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Responsive fluorescence probes for peroxynitrite: Design strategies, reaction mechanisms, and bioimaging applications

Guangzhao Liu, Xilei Xie, Yong Li, Jian Zhang, Xiaoyun Jiao, Xueyu Dou, Xu Wang and Bo Tang

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A coumarin-based probe for ultrafast visual detection of HClO/ClO- in environmental and biological systems

Hao Zhang, Kun He, Mingqing Luan, Hongshuo Zhang, Mingwei Zhang, Chaochao Ge, Xiufang Li, Ge Ding, Wantong Si and Xinchao Wang

Journal of Molecular Structure, 2026, 1364, 145894
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One-Pot Hydrothermal Synthesis of Carbon Dots as Fluorescent Probes for the Determination of Mercuric and Hypochlorite Ions

Hsin Lee, Yen-Chang Su, Hsiang-Hao Tang, Yu-Sheng Lee, Jan-Yee Lee, Cho-Chun Hu and Tai-Chia Chiu

Nanomaterials, 2021, 11, 1831
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A New Lipid‐Droplets‐Targeted Fluorescence Probe with Dual‐Reactive Sites for Specific Detection of ClO− in Living Cells

Zhao Li, Yuan Yang, Pei Yin, Zengming Yang, Bo Zhang, Shengjun Zhang, Bingyang Han, Jiawei Lv, Fenghao Dong and Hengchang Ma

ChemistrySelect, 2022, 7
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A novel tethered phenothiazine-coumarin fluorescence probe for rapid detection of hypochlorite ion and its applications

Yu Meng, Chang Liu, Huan Ding, Peiyu Yao, Song He and Xianshun Zeng

Dyes and Pigments, 2023, 218, 111470
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A triphenylamine-thiophene-based fluorescent probe for the dual-channel detection and imaging of hypochlorite and viscosity in live cells

Xiaoyuan Sun, Jianhua Wang, Zhuobin Shang, Hui Wang, Yu Wang and Shaomin Shuang

Journal of Molecular Liquids, 2024, 402, 124788
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Dual recognition site fluorescent probe for ratiometric imaging of hypochlorous acid in living cells and zebrafish

Xiaoyu Tang, Jiaxin Fan, Bin Lin and Yifeng Han

Journal of Molecular Structure, 2025, 1326, 141093
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Sensing Hypochlorite or pH variations in live cells and zebrafish with a novel dual-functional ratiometric and colorimetric chemosensor

Hong Chen, Jiamin Luo, Shijin Chen, Yueheng Qi, Tong Zhou, Xiumei Tian and Feng Ding

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 271, 120915
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A dual-responsive fluorescent probe based on cyanine and naphthalimide units for detecting HClO and H2S in living cells

Haichang Ding, Lisha Yue, Yin Ai, Zifan Zhu, Congbin Fan, Gang Liu and Shouzhi Pu

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 304, 123348
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Determination of Hydrogen Sulfide in Endoplasmic Reticulum by Two-Photon Fluorescence

Qingqing Ma, Haibin Xiao, Kai Wang, Xueli Liu and Yuying Liu

Analytical Letters, 2021, 54, 2687
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A rapid and selective phenothiazine-derived fluorescent probe for hypochlorous acid monitoring in living systems: from cellular imaging to in vivo systemic inflammatory response syndrome visualization

Zhipeng Sai, Zhifei Zhang, Ke You, Jingjing Xu, Chaochu Cui, Zhijun Yang and Chunpo Ge

Bioorganic Chemistry, 2026, 175, 109773
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Development of an activatable far-red fluorescent probe for rapid visualization of hypochlorous acid in live cells and mice with neuroinflammation

Long Mi, Changhe Niu, Jianqiang Chen, Feng Han and Xueying Ji

Front. Chem., 2024, 12
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A tosylhydrazone-based probe for the ratiometric fluorescent detection of hypochlorite in endoplasmic reticulum of living cells

Xiao-Chuang Chang, Xue-Feng Han, Bing-Jie Liu, Zi-Yi Jiang, Shuai-Ze Li, Yue-Ming Lv, Ao-Long Li, Yuan Wang and Wei-Na Wu

Journal of Molecular Structure, 2022, 1255, 132382
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Selective, stoichiometric and fast-response fluorescent probe based on 7-nitrobenz-2-oxa-1,3-diazole fluorophore for hypochlorous acid detection

Małgorzata Świerczyńska, Daniel Słowiński, Aleksandra Grzelakowska, Marcin Szala, Jarosław Romański, Karolina Pierzchała, Przemysław Siarkiewicz, Radosław Michalski and Radosław Podsiadły

Dyes and Pigments, 2021, 193, 109563
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Two smart coumarin-based fluorescent probes with AIE effect for sensing ClO- and imaging in living cells

Ao-Bei Zhang, Lei Jin, Qing-Ming Wang, Wen-Ling Wang and Yan-Li Chen

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 283, 121690
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Nano-sized aggregation induced emissive probe for highly sensitive hypochlorous acid detection

Arunkumar Kathiravan, Tamilvelan Manjunathan, Marappan Velusamy, Ajay Guru, Jesu Arockiaraj, Mariadoss Asha Jhonsi and Pushparathinam Gopinath

Dyes and Pigments, 2023, 210, 111016
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Ruthenium(II) Complex‐based Highly Specific Luminescence Light‐up Probe for Detecting HOCl via C(sp2)‐H Chlorination

Monosh Rabha, Sanjoy Kumar Sheet, Bhaskar Sen, Ibemhanbi Konthoujam, Kripamoy Aguan and Snehadrinarayan Khatua

ChemistrySelect, 2023, 8
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Single-atom iron fabricated electrochemical flexible sensor for detection of hypochlorite ions in water samples

Xin Chen, Zhujun Zou, Zhengyi Cang, Min Wang, Juejin Teng, Hong Bin Yang, Chunxian Guo and Fangxin Hu

Microchemical Journal, 2025, 211, 113145
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A red dicyanoisophorone-based fluorescent probe for monitoring cysteine fluctuations due to redox imbalances in living organisms even in the presence of other biological molecules

Wang Huayu, Ge Chunpo, Ni Tianjun, Yang Zhijun and Chang Kaiwen

Microchemical Journal, 2022, 174, 107093
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An ESIPT-based reversible ratiometric fluorescent sensor for detecting HClO/H2S redox cycle in living cells

Youming Shen, Xiangyang Zhang, Chunxiang Zhang and Yucai Tang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 285, 121881
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Effects of benzene-fused position on photophysical properties of benzocoumarin-based two-photon fluorescent probes for HClO detection

Minghui Geng, Xuexue Ma, Xiayu Cheng, Tongshu Zhang and Ke Zhao

Chinese Journal of Chemical Physics, 2025, 38, 212
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Methylthio‐substituted coumarin‐based fluorescent probe for highly specific and fast detection of hypochlorite and bioimaging application

Baijun Zhao, Wenwen Wang, Yanxi Song, Hongqi Li, Lin Jiang and Lingling Chu

Coloration Technology, 2024, 140, 483
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Novel fluorescence probe for ClO− in living cells: Based on FRET mechanism

Di Yang, Xiao-Tian Wu, Jun-Ya Ning, Bing-Yu Wei, Jun-Ying Miao, Bao-Xiang Zhao and Zhao-Min Lin

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 321, 124754
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A thiomorpholine-based fluorescent probe for the far-red hypochlorous acid monitoring

Małgorzata Świerczyńska, Daniel Słowiński, Radosław Michalski, Jarosław Romański and Radosław Podsiadły

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 289, 122193
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Recent Progress in Small Molecule-Based Chemiluminescent Probes for Reactive Oxygen and Nitrogen Species

Yalei Cao, Jie Yang, Bin Liu and Zhen Li

Chemical & Biomedical Imaging, 2025, 3, 792
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Ratiometric fluorescent probe with AIE characteristics for hypochlorite detection and biological imaging

Wei Bi, Xiangyuan Zhao, Xinjie Yang, Xushuo Yuan, Yanfei Lin, Kaimeng Xu, Li Liu, Heyang Zeng, Guanben Du and Lianpeng Zhang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 323, 124904
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6-Methylthiocoumarin-3-Carboxylic Acid as a Simple Chemosensor for the Fluorescence Detection of Hypochlorite in Aqueous Solution

Hongqi Li, Xinyan Jia, Baijun Zhao, Yanxi Song, Wan Zou and Haoran Chen

J Anal Chem, 2026, 81, 873
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New tool for diseases mechanism studies: Endoplasmic reticulum-targeted fluorescent probes

Qiannan Tang, Hening Li, Haoliang Hu and Linxi Chen

Dyes and Pigments, 2023, 219, 111634
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Facile access to a methylthiocoumarinyl formate as highly selective and sensitive fluorescent probe for hypochlorite

Yu Shi, Baijun Zhao, Ji Fan, Yong Zhao, Yanxi Song, Huachao Li, Zhiyu Shao and Hongqi Li

Chem. Pap., 2024, 78, 3607
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Responsive fluorescent probes for cellular microenvironment and redox small biomolecules

Li Zhang, Liangwei Zhang, Xia Zhang, Yang Zhao, Shujing Fang, Jinmao You and Lingxin Chen

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A ROS-responsive hydrogel incorporated with dental follicle stem cell-derived small extracellular vesicles promotes dental pulp repair by ameliorating oxidative stress

Mengjie Li, Jun Tian, Kangkang Yu, He Liu, Xiaoqi Yu, Nan Wang, Qimei Gong, Kun Li, Ya Shen and Xi Wei

Bioactive Materials, 2024, 36, 524
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A water-soluble phenothiazine-based fluorescent probe for selective detection and bioimaging of hypochlorite

Yang Yang, Yuxin Shao, Xiaoying Bao, Ning Xu, Wu Dong and Chao-Ying Gao

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 346, 126892
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Fluorescent Probes for HOCl Detection in Living Cells

V. E. Reut, I. V. Gorudko, D. V. Grigorieva, A. V. Sokolov and O. M. Panasenko

Russ J Bioorg Chem, 2022, 48, 467
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Dicyanoisophorone-based fluorescent probe with large Stokes shift for ratiometric detection and imaging of exogenous/endogenous hypochlorite in cell and zebrafish

Xiang-yu Kong, Shao-Min Shuang, Yue-tao Zhang, Yu Wang and Chuan Dong

Talanta, 2022, 242, 123293
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Unveiling cellular mysteries: Advances in BODIPY dyes for subcellular imaging

Haroon Ahmad, Sibtain Muhammad, Maria Mazhar, Ahmad Farhan, Muhammad Sohaib Iqbal, Hind Hiria, Chen Yu, Yinghe Zhang and Bing Guo

Coordination Chemistry Reviews, 2025, 526, 216383
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A novel reaction‐based colorimetric fluorescent probe based on phenothiazine for the detection of hypochlorite in real samples

Fei Yang, Limin Ma, Zhigang Zhao and Zhichuan Shi

J Chinese Chemical Soc, 2026, 73, 376
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A versatile lysosome-targeted probe for hypochlorous acid detection in live cells, zebrafish, and environmental waters

Xiaoyu Tang, Jiaxin Fan, Jianli Liao, Shuqi Tang and Yifeng Han

Journal of Photochemistry and Photobiology A: Chemistry, 2026, 473, 116922
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A ratiometric fluorescent probe based on oxabenzofluorene structure for the detection of peroxynitrite in mitochondria

Xiao-Lei Xue, Yang Wang, Ying Fang, Kun-Peng Wang, Shaojin Chen and Zhi-Qiang Hu

Journal of Luminescence, 2025, 283, 121258
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A near-infrared-emission aza-BODIPY-based fluorescent probe for fast, selective, and “turn-on” detection of HClO/ClO−

Wen-Jing Shi, Liu-Xia Feng, Xuan Wang, Yan Huang, Yong-Feng Wei, Yan-Yu Huang, Huai-Jin Ma, Wei Wang, Menghua Xiang and Liqian Gao

Talanta, 2021, 233, 122581
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A New and Fast-Response Fluorescent Probe for Monitoring Hypochlorous Acid Derived from Myeloperoxidase

Małgorzata Świerczyńska, Daniel Słowiński, Radosław Michalski, Jarosław Romański and Radosław Podsiadły

Molecules, 2023, 28, 6055
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Recent development in dual function fluorescence probes for HOCl and interaction with different bioactive molecules

Wajeeha Zareen, Nadeem Ahmed, Shahid Raza, Muhammad Ali Khan and Zahid Shafiq

Talanta, 2024, 277, 126374
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