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Cascade strategy for glucose oxidase-based synergistic cancer therapy using nanomaterials
Ruixuan He, Peida Yang, Aoxue Liu, Yueli Zhang, Yuqi Chen, Cong Chang and Bo Lu
J. Mater. Chem. B, 2023, 11, 9798
DOI: 10.1039/D3TB01325A

Plasmonic enhanced enzyme activity by catalytic cascade induced mutual benefit tumor starvation/immune/photothermal therapy
Xin Cheng, Zining Hao, Shuzhen Chu, Tiantian Zhang, Cong Cong, Lanxiang Liu, Weidong Zhang, Jianmin Gu, Song Ni, Desong Wang and Dawei Gao
Biomater. Sci., 2021, 9, 6116
DOI: 10.1039/D1BM00551K

The facile formation of hierarchical mesoporous silica nanocarriers for tumor-selective multimodal theranostics
Xiaoyan Guo, Man Zhu, Pingyun Yuan, Tao Liu, Ran Tian, Yongkang Bai, Yanmin Zhang and Xin Chen
Biomater. Sci., 2021, 9, 5237
DOI: 10.1039/D1BM00564B

Synchrotron radiation-based analysis of interactions at the nano–bio interface
Saima Hameed, Didar Baimanov, Xiumin Li, Ke Liu and Liming Wang
Environ. Sci.: Nano, 2022, 9, 3152
DOI: 10.1039/D2EN00408A

Ion interference and its combined therapies for cancer treatments
Xinkai Hu, Dongdong Guo and Nguyen Thi Kim Thanh
Nanoscale, 2026
DOI: 10.1039/D5NR04488J

Nanoplatform-based cascade engineering for cancer therapy
Jiajie Chen, Yufang Zhu, Chengtie Wu and Jianlin Shi
Chem. Soc. Rev., 2020, 49, 9057
DOI: 10.1039/D0CS00607F

A pH-activated autocatalytic nanoreactor for self-boosting Fenton-like chemodynamic therapy
Hongshuai Wu, Fanghui Chen, Dihai Gu, Chaoqun You and Baiwang Sun
Nanoscale, 2020, 12, 17319
DOI: 10.1039/D0NR03135F

Pickering emulsion templated proteinaceous microparticles as glutathione-responsive carriers for endocytosis in tumor cells
Weijie Jiang, Xin Guan, Wei Liu, Yunxing Li, Hang Jiang and To Ngai
Nanoscale Horiz., 2024, 9, 536
DOI: 10.1039/D3NH00551H

Fabrication of H2O2-driven nanoreactors for innovative cancer treatments
Ziliang Dong, Zhijuan Yang, Yu Hao and Liangzhu Feng
Nanoscale, 2019, 11, 16164
DOI: 10.1039/C9NR04418C

Self-evolved hydrogen peroxide boosts photothermal-promoted tumor-specific nanocatalytic therapy
Shanshan Gao, Xiangyu Lu, Piao Zhu, Han Lin, Luodan Yu, Heliang Yao, Chenyang Wei, Yu Chen and Jianlin Shi
J. Mater. Chem. B, 2019, 7, 3599
DOI: 10.1039/C9TB00525K

A glutathione-depleted prodrug platform of MnO2-coated hollow polydopamine nanospheres for effective cancer diagnosis and therapy
Liang Dong, Zhiai Xu, Shangjie An, Xiaodan Jia, Wen Zhang and Xiue Jiang
New J. Chem., 2020, 44, 7838
DOI: 10.1039/D0NJ01211D

A multifunctional oxygen-producing MnO2-based nanoplatform for tumor microenvironment-activated imaging and combination therapy in vitro
Chunlei Yang, Yazhou Liu, Sa Su, Na Gao, Jing Jing and Xiaoling Zhang
J. Mater. Chem. B, 2020, 8, 9943
DOI: 10.1039/D0TB00529K

Recent developments in bismuth oxyhalide-based functional nanomaterials for biomedical applications
Guobo Chen, Yuhao Li, Baolin Liu and Yuqing Miao
Biomater. Sci., 2022, 10, 5809
DOI: 10.1039/D2BM01182D

Multimodal therapies: glucose oxidase-triggered tumor starvation-induced synergism with enhanced chemodynamic therapy and chemotherapy
Kaiwu Cheng, Chuxuan Ling, Dihai Gu, Zhiguo Gao, Yaojia Li, Peijing An, Yu Zhang, Chaoqun You, Rui Zhang and Baiwang Sun
New J. Chem., 2020, 44, 1524
DOI: 10.1039/C9NJ05469C

Z-Scheme heterostructures for glucose oxidase-sensitized radiocatalysis and starvation therapy of tumors
Ze Wang, Lu Wang, Shuwei Liu, Mengsi Zhang, Yunfeng Li, Li Rong, Yi Liu and Hao Zhang
Nanoscale, 2022, 14, 2186
DOI: 10.1039/D1NR07096G

A double rare earth doped CD nanoplatform for nanocatalytic/starving-like synergistic therapy with GSH-depletion and enhanced reactive oxygen species generation
Shufeng Cui, Bin Wang, Changyu Zhai, Shanshan Wei, Hongyuan Zhang and Guoying Sun
J. Mater. Chem. B, 2023, 11, 7986
DOI: 10.1039/D3TB00959A

Inorganic nanomaterials with rapid clearance for biomedical applications
Xianwen Wang, Xiaoyan Zhong, Jianxiang Li, Zhuang Liu and Liang Cheng
Chem. Soc. Rev., 2021, 50, 8669
DOI: 10.1039/D0CS00461H

Skillfully collaborating chemosynthesis with GOx-enabled tumor survival microenvironment deteriorating strategy for amplified chemotherapy and enhanced tumor ablation
Runxin Lu, Lin Zhou, Qijun Liu, Siqi Wang, Chunyan Yang, Li Hai, Li Guo and Yong Wu
Biomater. Sci., 2021, 9, 1855
DOI: 10.1039/D0BM01950J

Tumor-specific nanomedicine via sequential catalytic reactions for accurate tumor therapy
Li Chen, Lu Zhao, Guoyang Hu, Ronghua Jin, Bolei Cai, Yongkang Bai and Xin Chen
J. Mater. Chem. B, 2020, 8, 6857
DOI: 10.1039/C9TB02812A

Hybrid theranostic microbubbles for ultrasound/photoacoustic imaging guided starvation/low-temperature photothermal/hypoxia-activated synergistic cancer therapy
Feng Tian, Xingjian Zhong, JunKai Zhao, Yutian Gu, Yadi Fan, Fan Shi, Yu Zhang, Youhua Tan, Wen Chen, Changqing Yi and Mo Yang
J. Mater. Chem. B, 2021, 9, 9358
DOI: 10.1039/D1TB01735G

A robust hybrid nanozyme@hydrogel platform as a biomimetic cascade bioreactor for combination antitumor therapy
Yijun Hao, Yandi Liu, Yingjiao Wu, Na Tao, Dongyang Lou, Juan Li, Xiaoyi Sun and You-Nian Liu
Biomater. Sci., 2020, 8, 1830
DOI: 10.1039/C9BM01837A

Remote-controlled multi-enzyme system for enhanced tumor therapy via dark/light relay catalysis
Ying Chen, Zi-Hao Li, Jing-Jing Hu, Si-Yuan Peng, Lei Rong, Yunxia Sun and Xian-Zheng Zhang
Nanoscale Horiz., 2020, 5, 283
DOI: 10.1039/C9NH00583H

Biodegradable nanomaterials for diagnosis and therapy of tumors
Dongmiao Cao, Liang Chen, Ziwen Zhang, Yu Luo, Linjing Zhao, Chunping Yuan, Jie Lu, Xijian Liu and Jingchao Li
J. Mater. Chem. B, 2023, 11, 1829
DOI: 10.1039/D2TB02591D

Cancer therapeutic strategies based on metal ions
Yang Liu, Yinghui Wang, Shuyan Song and Hongjie Zhang
Chem. Sci., 2021, 12, 12234
DOI: 10.1039/D1SC03516A

A novel multifunctional FePt/BP nanoplatform for synergistic photothermal/photodynamic/chemodynamic cancer therapies and photothermally-enhanced immunotherapy
Xiuxiu Yao, Baochan Yang, Shan Wang, Zhichao Dai, Dongsheng Zhang, Xiuwen Zheng and Qingyun Liu
J. Mater. Chem. B, 2020, 8, 8010
DOI: 10.1039/D0TB00411A

Glutathione-triggered nanoplatform for chemodynamic/metal-ion therapy
Min Liu, Hongshuai Wu, Senlin Wang, Jinzhong Hu and Baiwang Sun
J. Mater. Chem. B, 2021, 9, 9413
DOI: 10.1039/D1TB01330K

Nanomaterials for cascade promoted catalytic cancer therapy
Zongrui Tong, Yong Gao, Huang Yang, Weilin Wang and Zhengwei Mao
VIEW, 2021, 2
DOI: 10.1002/VIW.20200133

Programmable NIR‐II Photothermal‐Enhanced Starvation‐Primed Chemodynamic Therapy using Glucose Oxidase‐Functionalized Ancient Pigment Nanosheets
Chen Yang, Muhammad Rizwan Younis, Jing Zhang, Junle Qu, Jing Lin and Peng Huang
Small, 2020, 16
DOI: 10.1002/smll.202001518

Mesoporous Silica-Coated Silver Nanoframes as Drug-Delivery Vehicles for Chemo/Starvation/Metal Ion Multimodality Therapy
Yu Zhang, Yaojia Li, Zhiguo Gao, Bowen Ding, Peijing An, Xichen Zhang, Bowen Sun and Baiwang Sun
Langmuir, 2020, 36, 6345
DOI: 10.1021/acs.langmuir.0c00191

pH-Sensitive Polymeric Vesicles for GOx/BSO Delivery and Synergetic Starvation-Ferroptosis Therapy of Tumor
Yang Luo, Peng Yan, Xinyang Li, Jianwen Hou, Yi Wang and Shaobing Zhou
Biomacromolecules, 2021, 22, 4383
DOI: 10.1021/acs.biomac.1c00960

Tumor Microenvironment-Activatable Nanosystem Capable of Overcoming Multiple Therapeutic Obstacles for Augmenting Immuno/Metal-Ion Therapy
Qian Cheng, Xiaolei Shi, Yuzhe Chen, Qilin Li, Jiawei Wang, Heli Li, Lin Wang and Zheng Wang
ACS Nano, 2024, 18, 8996
DOI: 10.1021/acsnano.3c12745

Precise Subcellular Organelle Targeting for Boosting Endogenous‐Stimuli‐Mediated Tumor Therapy
Wenyao Zhen, Shangjie An, Shuqi Wang, Wenxue Hu, Yujie Li, Xiue Jiang and Jinghong Li
Advanced Materials, 2021, 33
DOI: 10.1002/adma.202101572

Magnetically retained and glucose-fueled hydroxyl radical nanogenerators for H2O2-self-supplying chemodynamic therapy of wound infections
Minhui Gong, Jiayu Xiao, Huan Li, Luo Hai, Ke Yang, Junqin Li, Zefeng Wang, Le Deng and Dinggeng He
Materials Science and Engineering: C, 2021, 131, 112522
DOI: 10.1016/j.msec.2021.112522

Nanocomposite hydrogel with multiple metal ions coupling for effective treatment of bacteria infected wound via cascade catalysis and tissue regeneration
Yating Liu, Wenyun Mu, Yu Wang, Tao Liu, Zhenzhen Peng and Xin Chen
Chemical Engineering Journal, 2025, 511, 161783
DOI: 10.1016/j.cej.2025.161783

Calcium-Overload-Mediated Tumor Therapy by Calcium Peroxide Nanoparticles
Meng Zhang, Ruixue Song, Yanyan Liu, Zhigao Yi, Xianfu Meng, Jiawen Zhang, Zhongmin Tang, Zhenwei Yao, Yang Liu, Xiaogang Liu and Wenbo Bu
Chem, 2019, 5, 2171
DOI: 10.1016/j.chempr.2019.06.003

Antimicrobial Action of Biocompatible Silver Microspheres and Their Role in the Potential Treatment of Fungal Keratitis
Hanhan Shi, Jieying Ding, Cancan Chen, Qinke Yao, Weijie Zhang, Yao Fu, Xiansong Wang and Jing Ruan
ACS Biomater. Sci. Eng., 2021, 7, 5090
DOI: 10.1021/acsbiomaterials.1c00815

Nano-ROS-generating approaches to cancer dynamic therapy: Lessons from nanoparticles
Qinyi Zhang, Qiuhua Luo, Zimeng Liu, Mengchi Sun and Xiao Dong
Chemical Engineering Journal, 2023, 457, 141225
DOI: 10.1016/j.cej.2022.141225

Iridium/ruthenium nanozyme reactors with cascade catalytic ability for synergistic oxidation therapy and starvation therapy in the treatment of breast cancer
Chunfang Wei, Yanan Liu, Xufeng Zhu, Xu Chen, Yanhui Zhou, Guanglong Yuan, Youcong Gong and Jie Liu
Biomaterials, 2020, 238, 119848
DOI: 10.1016/j.biomaterials.2020.119848

Biomimetic nanoreactor for targeted cancer starvation therapy and cascade amplificated chemotherapy
Fengying Shao, Yafeng Wu, Zhaoyan Tian and Songqin Liu
Biomaterials, 2021, 274, 120869
DOI: 10.1016/j.biomaterials.2021.120869

Tumor-responsive dynamic nanoassemblies for targeted imaging, therapy and microenvironment manipulation
Liang Ee Low, Jiahe Wu, Jiyoung Lee, Beng Ti Tey, Bey-Hing Goh, Jianqing Gao, Fangyuan Li and Daishun Ling
Journal of Controlled Release, 2020, 324, 69
DOI: 10.1016/j.jconrel.2020.05.014

Cascade-Reaction-Triggered Engineering Nanocatalytic Theranostics Reconstructing Tumor Microenvironment Through Synergistic Oxidative Damage and Aerobic Glycolysis Inhibition Against Colon Cancer
Ning-Hua Tan, Yongrong Yao, Yanqing Xu, Xing Zhao and Huachao Chen
SSRN Journal, 2021
DOI: 10.2139/ssrn.3994401

One-step reduction-encapsulated synthesis of Ag@polydopamine multicore-shell nanosystem for enhanced photoacoustic imaging and photothermal-chemodynamic cancer therapy
Xiao-Rui Li, Baoli Yin, Lei Gao, Xinhao Li, Hongwen Huang, Guosheng Song and Yi-Ge Zhou
Nano Res., 2022, 15, 8291
DOI: 10.1007/s12274-022-4474-4

Enzyme Mimics for Engineered Biomimetic Cascade Nanoreactors: Mechanism, Applications, and Prospects
Xianlong Zhang, Guoliang Li, Guang Chen, Di Wu, Yongning Wu and Tony D. James
Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202106139

Image‐Guided TME‐Improving Nano‐Platform for Ca2+ Signal Disturbance and Enhanced Tumor PDT
Yuping Jiang, Wei Meng, Lijuan Wu, Kai Shao, Lili Wang, Mengchao Ding, Jinsheng Shi and Xiaoying Kong
Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202100789

Multimodal Enzyme‐Carrying Suprastructures for Rapid and Sensitive Biocatalytic Cascade Reactions
Seong‐Min Jo, Jihye Kim, Ji Eun Lee, Frederik R. Wurm, Katharina Landfester and Sanghyuk Wooh
Advanced Science, 2022, 9
DOI: 10.1002/advs.202104884

Advancements in NADH Oxidase Nanozymes: Bridging Nanotechnology and Biomedical Applications
Dan Li, Juyang He, Guanyu Ding, Yan Xin, Fan Feng, Shuaining Ma, Lu Lin, Erkang Wang and Jin Wang
Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202402785

Diversified nanocarrier design to optimize glucose oxidase-mediated anti-tumor therapy: Strategy and progress
Yuhan Fu, Jialin Sun, Chunyu Yang, Weinan Li and Yanhong Wang
International Journal of Biological Macromolecules, 2025, 306, 141581
DOI: 10.1016/j.ijbiomac.2025.141581

Upconversion Nanoparticle-Based Cell Membrane-Coated cRGD Peptide Bioorthogonally Labeled Nanoplatform for Glioblastoma Treatment
Jingxin Mo, Xianjue Chen, Meiying Li, Wenxu Liu, Wei Zhao, Lee Yong Lim, Richard D. Tilley, J. Justin Gooding and Qinghua Li
ACS Appl. Mater. Interfaces, 2022, 14, 49454
DOI: 10.1021/acsami.2c11284

Hydroxyl radical-involved cancer therapy via Fenton reactions
Mengying Liu, Yun Xu, Yanjun Zhao, Zheng Wang and Dunyun Shi
Front. Chem. Sci. Eng., 2022, 16, 345
DOI: 10.1007/s11705-021-2077-3

Tumor-microenvironment-mediated second near-infrared light activation multifunctional cascade nanoenzyme for self-replenishing O2/H2O2 multimodal tumor therapy
Yu Chen, Haiqiong Cao, Chaoqun Jiang and Youbin Li
Journal of Colloid and Interface Science, 2025, 683, 930
DOI: 10.1016/j.jcis.2024.12.228

Hyaluronic Acid-Modified Au–Ag Alloy Nanoparticles for Radiation/Nanozyme/Ag+ Multimodal Synergistically Enhanced Cancer Therapy
Yu Chong, Jie Huang, Xiaoyu Xu, Chenggong Yu, Xingyu Ning, Saijun Fan and Zhijun Zhang
Bioconjugate Chem., 2020, 31, 1756
DOI: 10.1021/acs.bioconjchem.0c00224

Nanocatalytic medicine: An advanced catalysis-based imaging and therapy methodology
Lingdong Jiang, Zhaokui Jin and Qianjun He
Coordination Chemistry Reviews, 2025, 529, 216430
DOI: 10.1016/j.ccr.2024.216430

KCl Nanoparticles as Potential Inducer of Immunogenic Cell Death for Cancer Immunotherapy
Zhengjie Huang, Xiaohong Zhang, Yang Luo, Yi Wang and Shaobing Zhou
ACS Appl. Bio Mater., 2023, 6, 2404
DOI: 10.1021/acsabm.3c00219

Urchin-Shaped Metal Organic/Hydrogen-Bonded Framework Nanocomposite as a Multifunctional Nanoreactor for Catalysis-Enhanced Synergetic Therapy
Chunling Hu, Jiazhi Wang, Sainan Liu, Lihan Cai, Ying Zhou, Xiangjian Liu, Man Wang, Zhendong Liu and Maolin Pang
ACS Appl. Mater. Interfaces, 2021, 13, 4825
DOI: 10.1021/acsami.0c19584

Reallocating Cell Respiration Substrates for Cancer Therapy Using a Metabolism Regulator with an Intermembrane‐Translocatable Accessory
Qiu‐Yi Duan, Ya‐Xuan Zhu, Bai‐Hui Shan, Yuxin Guo, Ke‐Fei Xu, Hao‐Ran Jia and Fu‐Gen Wu
Adv Funct Materials, 2023, 33
DOI: 10.1002/adfm.202213636

Synergistic in-situ growth of silver nanoparticles with nanozyme activity for dual-mode biosensing and cancer theranostics
Xin Hai, Yuwei Li, Kaixin Yu, Shuzhen Yue, Yuanfang Li, Weiling Song, Sai Bi and Xueji Zhang
Chinese Chemical Letters, 2021, 32, 1215
DOI: 10.1016/j.cclet.2020.09.013

Multidimensional transitional metal-actuated nanoplatforms for cancer chemodynamic modulation
Yali Zhuang, Shuyan Han, Yifen Fang, Hai Huang and Jun Wu
Coordination Chemistry Reviews, 2022, 455, 214360
DOI: 10.1016/j.ccr.2021.214360

Biodegradable Multifunctional Nanotheranostic Based on Ag2S-Doped Hollow BSA-SiO2 for Enhancing ROS-Feedback Synergistic Antitumor Therapy
Ziliang Zheng, Rong Dai, Zhuo Jia, Xiaorong Yang, Yufei Qin, Shuo Rong, Xiaoyang Peng, Xianmei Xie, Yanyan Wang and Ruiping Zhang
ACS Appl. Mater. Interfaces, 2020, 12, 54356
DOI: 10.1021/acsami.0c14855

Glucose oxidase assisted AgNPs/lysozyme composite coating for enhancing the controllable and rapid antibacterial properties of textiles
Ning Zhang, Man Zhou, Yonggui Li, Xiang Mi and Qiang Wang
Industrial Crops and Products, 2026, 242, 122931
DOI: 10.1016/j.indcrop.2026.122931

Near infrared light-triggered metal ion and photodynamic therapy based on AgNPs/porphyrinic MOFs for tumors and pathogens elimination
Lu Zhang, Qian Cheng, Chuxin Li, Xuan Zeng and Xian-Zheng Zhang
Biomaterials, 2020, 248, 120029
DOI: 10.1016/j.biomaterials.2020.120029

Sulfite‐Inserted MgAl Layered Double Hydroxides Loaded with Glucose Oxidase to Enable SO2‐Mediated Synergistic Tumor Therapy
Qiang Chu, Linhua Liao, Bin Liu, Gaorong Han and Xiang Li
Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202103262

NIR-II driven plasmon-enhanced cascade reaction for tumor microenvironment-regulated catalytic therapy based on bio-breakable Au–Ag nanozyme
Min Xu, Qianglan Lu, Yiling Song, Lifang Yang, Chuchu Ren, Wen Li, Ping Liu, Yule Wang, Yan Zhu and Nan Li
Nano Res., 2020, 13, 2118
DOI: 10.1007/s12274-020-2818-5

Glucose Oxidase‐Instructed Multimodal Synergistic Cancer Therapy
Lian‐Hua Fu, Chao Qi, Yan‐Ru Hu, Jing Lin and Peng Huang
Advanced Materials, 2019, 31
DOI: 10.1002/adma.201808325

Catalytic Nanoparticles in Biomedical Applications: Exploiting Advanced Nanozymes for Therapeutics and Diagnostics
Divinah Manoharan, Liu‐Chun Wang, Ying‐Chi Chen, Wei‐Peng Li and Chen‐Sheng Yeh
Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202400746

Recent Development on Controlled Synthesis of Mn‐Based Nanostructures for Bioimaging and Cancer Therapy
Juan Ruan and Haisheng Qian
Advanced Therapeutics, 2021, 4
DOI: 10.1002/adtp.202100018

Schottky Junction Nanozyme Based on Mn-Bridged Co-Phthalocyanines and Ti3C2Tx Nanosheets Boosts Integrative Type I and II Photosensitization for Multimodal Cancer Therapy
Fenghe Duan, Qiaojuan Jia, Gaolei Liang, Mengfei Wang, Lei Zhu, Kevin J. McHugh, Lihong Jing, Miao Du and Zhihong Zhang
ACS Nano, 2023, 17, 11290
DOI: 10.1021/acsnano.2c12270

Zinc‐based metal‐organic frameworks as efficient carriers for anticancer drug to reduce toxicity and increase efficacy
Dong‐Wei Ma, Jing‐Sheng Lu, Xiang‐Xin Cao, Yan‐Wei Cheng, Gang Wang, Zi‐Qian Zhang, Bo‐Cheng Chen, Ning Lin and Qing Chen
Rare Metals, 2024, 43, 5152
DOI: 10.1007/s12598-024-02928-x

Cold atmospheric plasma as a novel “drug” for cancer therapy
Danni Fu, Shiyao Lin, Qingnan Xu, Fei Cao, Israr Khan, Shu Xu, Zhenhua Li, Zhaowei Chen, Qiujie Fang, Guojun Chen, Zejun Wang and Zhitong Chen
Journal of Controlled Release, 2025, 386, 114118
DOI: 10.1016/j.jconrel.2025.114118

Photodynamic and Its Concomitant Ion‐Interference Synergistic Therapies Based on Functional Hierarchically Mesoporous MOFs
Miao He, Ke Li, Jian Yang, Qinghua Wang and Jinlou Gu
Small, 2022, 18
DOI: 10.1002/smll.202204295

Synergistic Multimodal Cancer Therapy Using Glucose Oxidase@CuS Nanocomposites
Parbeen Singh, Brian Youden, Yikun Yang, Yongli Chen, Andrew Carrier, Shufen Cui, Ken Oakes, Mark Servos, Runqing Jiang and Xu Zhang
ACS Appl. Mater. Interfaces, 2021, 13, 41464
DOI: 10.1021/acsami.1c12235

Glucose oxidase and metal catalysts combined tumor synergistic therapy: mechanism, advance and nanodelivery system
Yuhan Fu, Jialin Sun, Yanhong Wang and Weinan Li
J Nanobiotechnol, 2023, 21
DOI: 10.1186/s12951-023-02158-w

Natural enzyme cascade bimetallic sulfide MoCuSx nanozyme for synergistic photothermal/photodynamic enhanced chemodynamic antimicrobial therapy of wound infection
Caiyun Xu, Junqin Li, Chunlei Ou, Jing Yang, Shuting Fu, Weiqing Hu, Li Wang, Zefeng Wang, Luo Hai, Le Deng and Dinggeng He
Chemical Engineering Journal, 2024, 499, 156170
DOI: 10.1016/j.cej.2024.156170

Nanocatalytic Theranostics with Glutathione Depletion and Enhanced Reactive Oxygen Species Generation for Efficient Cancer Therapy
Lian‐Hua Fu, Yilin Wan, Chao Qi, Jin He, Chunying Li, Chen Yang, Han Xu, Jing Lin and Peng Huang
Advanced Materials, 2021, 33
DOI: 10.1002/adma.202006892

Nanoreactor of “butterfly effect” inciting a triple interlocked combination of starvation/chemo/metal ion therapy by remodeling tumor microenvironment
Zining Hao, Xin Cheng, Cong Cong, Xuwu Zhang, Weidong Zhang, Qianqian Zhao, Shuai Wang and Dawei Gao
Chemical Engineering Journal, 2021, 405, 126571
DOI: 10.1016/j.cej.2020.126571

The synergistic effect of eucalyptus oil and retinoic acid on human esophagus cancer cell line SK-GT-4
Saba M. J. Falih, Sarah T. Al-Saray, Abdulbari A. Alfaris and Ali A. A. Al-Ali
Egypt J Med Hum Genet, 2022, 23
DOI: 10.1186/s43042-022-00259-z

Bioinspired protein corona strategy enhanced biocompatibility of Ag-Hybrid hollow Au nanoshells for surface-enhanced Raman scattering imaging and on-demand activation tumor-phototherapy
Jian He, Qiaolin Wei, Shoujie Wang, Shiyuan Hua and Min Zhou
Biomaterials, 2021, 271, 120734
DOI: 10.1016/j.biomaterials.2021.120734

Self-assembled FeS-based cascade bioreactor with enhanced tumor penetration and synergistic treatments to trigger robust cancer immunotherapy
Hao Ren, Jiahui Yong, Qingqing Yang, Zhen Yang, Zhangya Liu, Yan Xu, Hao Wang, Xing Jiang, Wenjun Miao and Xueming Li
Acta Pharmaceutica Sinica B, 2021, 11, 3244
DOI: 10.1016/j.apsb.2021.05.005

Programmable starving-photodynamic synergistic cancer therapy
Leli Zeng, Kai Huang, Yilin Wan, Jing Zhang, Xikuang Yao, Chao Jiang, Jing Lin and Peng Huang
Sci. China Mater., 2020, 63, 611
DOI: 10.1007/s40843-019-1226-8

Platinum–Titania Schottky Junction as Nanosonosensitizer, Glucose Scavenger, and Tumor Microenvironment-Modulator for Promoted Cancer Treatment
Yinmin Zhao, Jiahui Liu, Mengting He, Qi Dong, Lei Zhang, Zhigang Xu, Yuejun Kang and Peng Xue
ACS Nano, 2022, 16, 12118
DOI: 10.1021/acsnano.2c02540

Prodrug-Based Nanoreactors with Tumor-Specific In Situ Activation for Multisynergistic Cancer Therapy
Cui Ren, Huifang Liu, Fangfang Lv, Wencong Zhao, Shutao Gao, Xinjian Yang, Yi Jin, Yanli Tan, Jinchao Zhang, Xing-Jie Liang and Zhenhua Li
ACS Appl. Mater. Interfaces, 2020, 12, 34667
DOI: 10.1021/acsami.0c09489

Cascade-reaction-triggered engineering nanocatalytic theranostics reconstructing tumor microenvironment through synergistic oxidative damage and aerobic glycolysis inhibition against colon cancer
Yongrong Yao, Yanqing Xu, Xing Zhao, Huachao Chen and Ninghua Tan
Chemical Engineering Journal, 2023, 451, 138336
DOI: 10.1016/j.cej.2022.138336

Smart Porous Core–Shell Cuprous Oxide Nanocatalyst with High Biocompatibility for Acid‐Triggered Chemo/Chemodynamic Synergistic Therapy
Hongshuai Wu, Fanghui Chen, Chaoqun You, Yu Zhang, Baiwang Sun and Qing Zhu
Small, 2020, 16
DOI: 10.1002/smll.202001805

Bioactive nanomaterials for ion‐interference therapy
Yanyan Liu, Meng Zhang and Wenbo Bu
VIEW, 2020, 1
DOI: 10.1002/viw2.18

A cascade nanosystem with “Triple-Linkage” effect for enhanced photothermal and activatable metal ion therapy for hepatocellular carcinoma
Shuo Yu, Huan Shen, Xi Chen, Hong Wang, Chenyang He, Tinghua Hu, Gang Cao and Lu Zhang
J Nanobiotechnol, 2024, 22
DOI: 10.1186/s12951-024-02551-z

A Dual Functional Nanoreactor for Synergistic Starvation and Photodynamic Therapy
Yang Zhu, Hongdong Shi, Tuanwei Li, Jianing Yu, Zhengxi Guo, Junjie Cheng and Yangzhong Liu
ACS Appl. Mater. Interfaces, 2020, 12, 18309
DOI: 10.1021/acsami.0c01039

Arsenic Prodrug-Mediated Tumor Microenvironment Modulation Platform for Synergetic Glioblastoma Therapy
Jiliang Yan, Sumaira Hanif, Dongya Zhang, Muhammad Ismail, Xiao Wang, Qianjin Li, Bingyang Shi, Pir Muhammad and Haigang Wu
ACS Appl. Mater. Interfaces, 2022, 14, 36487
DOI: 10.1021/acsami.2c12076

Recent Advances in Glucose‐Oxidase‐Based Nanocomposites for Tumor Therapy
Man Wang, Dongmei Wang, Qing Chen, Chunxia Li, Zhengquan Li and Jun Lin
Small, 2019, 15
DOI: 10.1002/smll.201903895

Manganese carbonate nanoparticles‐mediated mitochondrial dysfunction for enhanced sonodynamic therapy
Haoyuan Zhang, Xueting Pan, Qingyuan Wu, Juan Guo, Chaohui Wang and Huiyu Liu
Exploration, 2021, 1
DOI: 10.1002/EXP.20210010

Janus γ-Fe2O3/SiO2-based nanotheranostics for dual-modal imaging and enhanced synergistic cancer starvation/chemodynamic therapy
Yifan Zhang, Yilin Wan, Yunyan Liao, Yanjie Hu, Tao Jiang, Ting He, Wei Bi, Jing Lin, Peng Gong, Longhua Tang and Peng Huang
Science Bulletin, 2020, 65, 564
DOI: 10.1016/j.scib.2019.12.024

Polymersome nanoreactors with tumor pH-triggered selective membrane permeability for prodrug delivery, activation, and combined oxidation-chemotherapy
Jean Felix Mukerabigwi, Wei Yin, Zengshi Zha, Wendong Ke, Yuheng Wang, Weijian Chen, Abd Al-Wali Mohammed Mohammed Japir, Yi Wang and Zhishen Ge
Journal of Controlled Release, 2019, 303, 209
DOI: 10.1016/j.jconrel.2019.04.032

Rational Construction of Fluorescence Turn-Off Fluorinated Carbon Fiber/Ag Composites and Their Anticancer and Antibacterial Activities
Dandan Wang, Jingyi Peng, Yan Huang, Lu Sun, Mingyue Liu, Hui Li, Mianran Chao, Peiwei Gong, Zhe Liu and Jinmao You
ACS Appl. Bio Mater., 2021, 4, 1749
DOI: 10.1021/acsabm.0c01503

Dual-mode glucose nanosensor as an activatable theranostic platform for cancer cell recognition and cascades-enhanced synergetic therapy
Xin Hai, Xueying Zhu, Kaixin Yu, Shuzhen Yue, Weiling Song and Sai Bi
Biosensors and Bioelectronics, 2021, 192, 113544
DOI: 10.1016/j.bios.2021.113544

A Three-in-one ZIFs-Derived CuCo(O)/GOx@PCNs Hybrid Cascade Nanozyme for Immunotherapy/Enhanced Starvation/Photothermal Therapy
Qi Wang, Dongguang Niu, Jinsheng Shi and Lili Wang
ACS Appl. Mater. Interfaces, 2021, 13, 11683
DOI: 10.1021/acsami.1c01006

Light-triggered plasmonic vesicles with enhanced catalytic activity of glucose oxidase for programmable photothermal/starvation therapy
Zhuoting Deng, Yaling He, Muhammad Rizwan Younis, Shan Lei, Chao Jiang, Yanyan Yuan, Peng Huang and Jing Lin
Sci. China Mater., 2021, 64, 1291
DOI: 10.1007/s40843-020-1502-0

Glucose and Lactate Cooperatively Deprived by a PD-1-Presenting Nanoemulsion for Potentiated Antitumor Immunotherapy
Yifan Zhang, Penghang Chen, Weihua Wen, Xiquan Qian, Ting He, Lian-Hua Fu, Jing Lin and Peng Huang
ACS Nano, 2026
DOI: 10.1021/acsnano.5c19115

Glucose Metabolism Intervention-Facilitated Nanomedicine Therapy
Zhiyan Li, Xianghui Li, Shichao Ai, Song Liu and Wenxian Guan
IJN, 2022, Volume 17, 2707
DOI: 10.2147/IJN.S364840

Antineoplastic Enzyme as Drug Carrier with Activatable Catalytic Activity for Efficient Combined Therapy
Yifan Zhang, Shanshan Jiang, Jing Lin and Peng Huang
Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202208583

Noble Metal Nanoparticle-Based Photothermal Therapy: Development and Application in Effective Cancer Therapy
Shujie Yu, Guoyu Xia, Nan Yang, Longlong Yuan, Jianmin Li, Qingluo Wang, Dingyang Li, Lijun Ding, Zhongxiong Fan and Jinyao Li
IJMS, 2024, 25, 5632
DOI: 10.3390/ijms25115632

A multifunctional drug delivery system based on switchable peptide-stabilized emulsions
Daniel Boas, Alexander van Teijlingen, Zohar Shpilt, Deborah E. Shalev, Edit Y. Tshuva, Tell Tuttle and Meital Reches
Chem, 2024, 10, 1821
DOI: 10.1016/j.chempr.2024.02.003

MMP-2/GSH-responsive nanobomb for tumor chemo-immunotherapy with hierarchical delivery and TAMs re-education by regulating hbegf-activated ERK/MAPK signal pathway
Xinmin Zheng, Xiang Li, Guolin Shi, Yidan Zhou, Jinxiao Yan, Hao Zhang, Xiru Liu, Jiangong Zhang, Yu Liu, Liangliang Dai and Hui Yang
Chemical Engineering Journal, 2024, 491, 152174
DOI: 10.1016/j.cej.2024.152174

Biodegradable Manganese-Doped Calcium Phosphate Nanotheranostics for Traceable Cascade Reaction-Enhanced Anti-Tumor Therapy
Lian-Hua Fu, Yan-Ru Hu, Chao Qi, Ting He, Shanshan Jiang, Chao Jiang, Jin He, Junle Qu, Jing Lin and Peng Huang
ACS Nano, 2019, 13, 13985
DOI: 10.1021/acsnano.9b05836

Enhanced Cancer Starvation Therapy Based on Glucose Oxidase/3-Methyladenine-Loaded Dendritic Mesoporous OrganoSilicon Nanoparticles
Fan Wu, Yang Liu, Hui Cheng, Yun Meng, Jieyun Shi, Yang Chen and Yelin Wu
Biomolecules, 2021, 11, 1363
DOI: 10.3390/biom11091363

Delivering metal ions by nanomaterials: Turning metal ions into drug-like cancer theranostic agents
Chenguang Liu, Lingxiao Guo, Yong Wang, Jianting Zhang and Caiyun Fu
Coordination Chemistry Reviews, 2023, 494, 215332
DOI: 10.1016/j.ccr.2023.215332

Recent advances in metallic nanostructure-based photothermal therapy in the management of cancer metastasis
Rukaiah Fatma Begum, N. Afreen, S. Nirenjen, S. Ankul Singh, Sudarshan Singh and Bhupendra G. Prajapati
Med Oncol, 2025, 42
DOI: 10.1007/s12032-025-03075-8

Virus-Like Fe3O4@Bi2S3 Nanozymes with Resistance-Free Apoptotic Hyperthermia-Augmented Nanozymitic Activity for Enhanced Synergetic Cancer Therapy
Yajie Zhao, Binbin Ding, Xiao Xiao, Fan Jiang, Meifang Wang, Zhiyao Hou, Bengang Xing, Bo Teng, Ziyong Cheng, Ping’an Ma and Jun Lin
ACS Appl. Mater. Interfaces, 2020, 12, 11320
DOI: 10.1021/acsami.9b20661

Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy
Liangliang Dai, Mengjiao Yao, Zhenxiang Fu, Xiang Li, Xinmin Zheng, Siyu Meng, Zhang Yuan, Kaiyong Cai, Hui Yang and Yanli Zhao
Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-30436-y

Focused starvation of tumor cells using glucose oxidase: A comprehensive review
Shivanshu Agrawal, Gireesh K. Singh and Sanjay Tiwari
International Journal of Biological Macromolecules, 2024, 281, 136444
DOI: 10.1016/j.ijbiomac.2024.136444

A Versatile Calcium Phosphate Nanogenerator for Tumor Microenvironment‐activated Cancer Synergistic Therapy
Lian‐Hua Fu, Chunying Li, Weimin Yin, Yan‐Ru Hu, Tuanwei Sun, Yilin Wan, Jing Lin, Zhiming Li and Peng Huang
Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202101563

Prussian blue and its analogue nanoparticles: Appealing nanotheranostics for malignant tumor
Xinyu Cui, Yingying Niu, Yong Yang, Fuyang Zhao, Yuanyuan Yin, Lei Tong, Jinxia Gao, Wenxiu Shi, Xue Shen, Qi Zeng, Wei Zong, Deng Pan, Jingyi Peng, Xuefeng Tang, Fengyuan Zhao, Fangyu Jiao, Wencai Hao, Haoran Li, Sixuan Liu, Xiaoyang Li, Xiaojun Han and Miaojing Li
Coordination Chemistry Reviews, 2026, 563, 218005
DOI: 10.1016/j.ccr.2026.218005

Lactate‐Oxidase‐Instructed Cancer Diagnosis and Therapy
Shanshan Jiang, Xin Chen, Jing Lin and Peng Huang
Advanced Materials, 2023, 35
DOI: 10.1002/adma.202207951

Enzyme‐Mediated Tumor Starvation and Phototherapy Enhance Mild‐Temperature Photothermal Therapy
Ge Gao, Yao‐Wen Jiang, Yuxin Guo, Hao‐Ran Jia, Xiaotong Cheng, Yu Deng, Xin‐Wang Yu, Ya‐Xuan Zhu, Hao‐Yue Guo, Wei Sun, Xiaoyang Liu, Jing Zhao, Shihe Yang, Zhi‐Wu Yu, Fatima Maria Sierra Raya, Gaolin Liang and Fu‐Gen Wu
Adv Funct Materials, 2020, 30
DOI: 10.1002/adfm.201909391

MOF-shielded and glucose-responsive ultrasmall silver nano-factory for highly-efficient anticancer and antibacterial therapy
Yaojia Li, Zhiguo Gao, Yu Zhang, Fanghui Chen, Peijing An, Hongshuai Wu, Chaoqun You and Baiwang Sun
Chemical Engineering Journal, 2021, 416, 127610
DOI: 10.1016/j.cej.2020.127610

Glucose oxidase‐instructed biomineralization of calcium‐based biomaterials for biomedical applications
Lian‐Hua Fu, Chao Qi, Tuanwei Sun, Kai Huang, Jing Lin and Peng Huang
Exploration, 2023, 3
DOI: 10.1002/EXP.20210110

Tumor-activatable biomineralized nanotherapeutics for integrative glucose starvation and sensitized metformin therapy
Hong Wen, Yang Fei, Ruisi Cai, Xuemei Yao, Yanan Li, Xuan Wang, Chencheng Xue, Yan Hu, Menghuan Li and Zhong Luo
Biomaterials, 2021, 278, 121165
DOI: 10.1016/j.biomaterials.2021.121165

ROS-based dynamic therapy synergy with modulating tumor cell-microenvironment mediated by inorganic nanomedicine
Xiaoyan Zhong, Xianwen Wang, Jianxiang Li, Jun Hu, Liang Cheng and Xiangliang Yang
Coordination Chemistry Reviews, 2021, 437, 213828
DOI: 10.1016/j.ccr.2021.213828

New anti-cancer explorations based on metal ions
Han Hu, Qi Xu, Zhimin Mo, Xiaoxi Hu, Qianyuan He, Zhanjie Zhang and Zushun Xu
J Nanobiotechnol, 2022, 20
DOI: 10.1186/s12951-022-01661-w

Glucose Oxidase‐Related Cancer Therapies
Chunhui Wang, Jingxian Yang, Chunyan Dong and Shuo Shi
Advanced Therapeutics, 2020, 3
DOI: 10.1002/adtp.202000110

Dual catalytic cascaded nanoplatform for photo/chemodynamic/starvation synergistic therapy
Dihai Gu, Zhikun Liu, Hongshuai Wu, Peijing An, Xu Zhi, Yujie Yin, Wen Liu and Baiwang Sun
Colloids and Surfaces B: Biointerfaces, 2021, 199, 111538
DOI: 10.1016/j.colsurfb.2020.111538

Emerging glucose oxidase-delivering nanomedicines for enhanced tumor therapy
Kaiyue Song, Jiang Ming, Bailong Tao, Feng Zhao, Shaorong Huang, Wencheng Wu, Cong Jiang and Xianglong Li
Journal of Controlled Release, 2025, 381, 113580
DOI: 10.1016/j.jconrel.2025.02.076

Advanced Cancer Starvation Therapy by Simultaneous Deprivation of Lactate and Glucose Using a MOF Nanoplatform
Jiantao Yu, Zixiang Wei, Qing Li, Feiyan Wan, Zhicong Chao, Xindan Zhang, Li Lin, Hong Meng and Leilei Tian
Advanced Science, 2021, 8
DOI: 10.1002/advs.202101467

Antineoplastic Enzyme as Drug Carrier with Activatable Catalytic Activity for Efficient Combined Therapy
Yifan Zhang, Shanshan Jiang, Jing Lin and Peng Huang
Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202208583

Subcellular organelle-mediated precise delivery of nanomedicines: Advances and applications in cancer therapy
Wenli Dang, Tongcan Cui, Guorui Jiao, Jiawei Li and Zhidong Liu
Journal of Drug Delivery Science and Technology, 2025, 112, 107261
DOI: 10.1016/j.jddst.2025.107261

Cascade Catalytic Nanoplatform Based on “Butterfly Effect” for Enhanced Immunotherapy
Yanjiang Shao, Zeying Wang, Yutong Hao, Xueli Zhang, Ning Wang, Kunlun Chen, Junbiao Chang, Qianhua Feng and Zhenzhong Zhang
Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202002171

Application and progress of nanozymes in antitumor therapy
Gaihua He, Chao Mei, Chenbo Chen, Xiao Liu, Jiaxuan Wu, Yue Deng and Ye Liao
International Journal of Biological Macromolecules, 2024, 265, 130960
DOI: 10.1016/j.ijbiomac.2024.130960

Boosting cisplatin chemotherapy by nanomotor-enhanced tumor penetration and DNA adducts formation
Lihua Xu, Kaixiang Zhang, Xing Ma, Yingying Li, Yajie Jin, Chenglin Liang, Yong Wang, Wendi Duan, Hongling Zhang, Zhenzhong Zhang, Jinjin Shi, Junjie Liu, Yunlong Wang and Wentao Li
J Nanobiotechnol, 2022, 20
DOI: 10.1186/s12951-022-01622-3