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Evidence for the synthesis of an unusual high spin (S= 7/2) [Cu–3Fe–4S] cluster in the radical-SAM enzyme RSAD2 (viperin)

K. Honarmand Ebrahimi, C. Silveira and S. Todorovic

Chem. Commun., 2018, 54, 8614
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Intrinsic Immune Mechanisms Restricting Human Cytomegalovirus Replication

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Viruses, 2021, 13, 179
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RSAD2 is abundant in atherosclerotic plaques and promotes interferon-induced CXCR3-chemokines in human smooth muscle cells

Assim Hayderi, Ashok K. Kumawat, Vladimir S. Shavva, Mats Dreifaldt, Birgitta Sigvant, Marcelo H. Petri, Björn Kragsterman, Peder S. Olofsson, Allan Sirsjö and Liza U. Ljungberg

Sci Rep, 2024, 14
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Multi-omics and in-silico approach reveals AURKA, AURKB, and RSAD2 as therapeutic biomarkers in OSCC progression

Alvea Tasneem, Manish Singh, Prithvi Singh and Ravins Dohare

Journal of Biomolecular Structure and Dynamics, 2026, 44, 823
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Integrative Analysis of Shared Pathogenic Genes and Potential Mechanisms in Gardnerella vaginalis and Persistent HPV16 Infection

Ye Li, Yue Wang, Xianhua Liu, Huifeng Xue, Liying Wang, Maotong Zhang, Pengming Sun and Tomasz Brzozowski

Mediators of Inflammation, 2025, 2025
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Analysis of vitamin D-induced immunomodulatory gene expression changes in type 1 diabetes: from computational prediction to experimental validation

Safin Hussein, Azam Mahmoudi-aznaveh, Shahram Nekoeian, Karzan Qurbani, Mohammad Panji, Pooya Zakeri, Fatemeh Bandarian, Elahe Motevaseli and Zahra Azizi

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Transcriptome analysis reveals modulation of the STAT family in PEDV-infected IPEC-J2 cells

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BMC Genomics, 2020, 21
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Distinct Gene Expression Profiles in Colonic Organoids from Normotensive and the Spontaneously Hypertensive Rats

Jing Li, Elaine M. Richards, Eileen M. Handberg, Carl J. Pepine and Mohan K. Raizada

Cells, 2021, 10, 1523
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Molecular cloning and functional characterization of HMGB1 and HMGB2 in large yellow croaker Larimichthys crocea

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Fish & Shellfish Immunology, 2022, 127, 855
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RSAD2 Is an Effective Target for High-Yield Vaccine Production in MDCK Cells

Zilin Qiao, Yuejiao Liao, Mengyuan Pei, Zhenyu Qiu, Zhenbin Liu, Dongwu Jin, Jiayou Zhang, Zhongren Ma and Xiaoming Yang

Viruses, 2022, 14, 2587
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Identification of duck type II interferon-stimulated genes and revelation of duIFI35 inhibition of H5N6 AIV replication by promoting apoptosis

Tao Zhang, Na Yang, Lulu Ma, Fengxiang Xu, Xiaobing Lin, Jiangwu Huang, Fei Gao, Ming Liao, Min Feng and Manman Dai

Vet Res, 2026, 57
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Rsad2 is necessary for mouse dendritic cell maturation via the IRF7-mediated signaling pathway

Ji-Su Jang, Jun-Ho Lee, Nam-Chul Jung, So-Yeon Choi, Soo-Yeoun Park, Ji-Young Yoo, Jie-Young Song, Han Geuk Seo, Hyun Soo Lee and Dae-Seog Lim

Cell Death Dis, 2018, 9
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Pakorn Sagulkoo, Apichat Suratanee and Kitiporn Plaimas

Biomolecules, 2022, 12, 690
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Human Cytomegalovirus miR-US33as-5p Targets IFNAR1 to Achieve Immune Evasion During Both Lytic and Latent Infection

Qian Zhang, Xin Song, Ping Ma, Liping Lv, Yangyang Zhang, Jiang Deng and Yanyu Zhang

Front. Immunol., 2021, 12
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Tick-Borne Flaviviruses and the Type I Interferon Response

Richard Lindqvist, Arunkumar Upadhyay and Anna K. Överby

Viruses, 2018, 10, 340
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Enhancement of transgene expression by the β-catenin inhibitor iCRT14

Kyle Spivack, Christine Muzzelo, Matthew Hall, Eric Warga, Christopher Neely, Holly Slepian, Alyssa Cunningham, Matthew Tucker and Jacob Elmer

Plasmid, 2021, 114, 102556
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Metabolism-Based Gene Differences in Neurons Expressing Hyperphosphorylated AT8− Positive (AT8+) Tau in Alzheimer’s Disease

Audra York, Angela Everhart, Michael P. Vitek, Kirby W. Gottschalk and Carol A. Colton

ASN Neuro, 2021, 13
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Sex-specific gene expression in the blood of four primates

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Genomics, 2021, 113, 2605
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A lipidomic view of SARS-CoV-2

Kourosh H. Ebrahimi and James S.O. McCullagh

Bioscience Reports, 2021, 41
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Iron–sulfur clusters as inhibitors and catalysts of viral replication

Kourosh Honarmand Ebrahimi, Simone Ciofi-Baffoni, Peter-Leon Hagedoorn, Yvain Nicolet, Nick E. Le Brun, Wilfred R. Hagen and Fraser A. Armstrong

Nat. Chem., 2022, 14, 253
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Ion-Exchange Chromatography Coupled to Mass Spectrometry in Life Science, Environmental, and Medical Research

Judith B. Ngere, Kourosh H. Ebrahimi, Rachel Williams, Elisabete Pires, John Walsby-Tickle and James S. O. McCullagh

Anal. Chem., 2023, 95, 152
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Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26.ZEBOV/MVA-BN-Filo

Fabiola Blengio, Hakim Hocini, Laura Richert, Cécile Lefebvre, Mélany Durand, Boris Hejblum, Pascaline Tisserand, Chelsea McLean, Kerstin Luhn, Rodolphe Thiebaut and Yves Levy

Cell Reports, 2023, 42, 113101
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Upregulation of the interferon-inducible antiviral gene RSAD2 in neuroendocrine prostate cancer via PVT1 exon 9 dependent and independent pathways

Rachel E. Bonacci, Meghan McGill, Nu Thuy Anh Le, Murtaza Barkarar, Colin Finnegan, Maya Wilson, Oluwabusola Ajagbe, Chinedum C. Udekwu, Kathryn Gorski, Jyothi Manohar, Andrea Sboner and Olorunseun O. Ogunwobi

Journal of Biological Chemistry, 2025, 301, 108370
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Change in Long Non-Coding RNA Expression Profile Related to the Antagonistic Effect of Clostridium perfringens Type C on Piglet Spleen

Zunqiang Yan, Pengfei Wang, Qiaoli Yang, Xiaoli Gao, Shuangbao Gun and Xiaoyu Huang

CIMB, 2023, 45, 2309
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Resolving candidate genes of duck ovarian tissue transplantation via RNA-Seq and expression network analyses

Qingming Qin, Rongxu Liu, Zhili Li, Midi Liu, Xian Wu, Huimin Wang, Shuailiang Yang, Xuyang Sun and Xianguo Yi

Poultry Science, 2024, 103, 103788
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Integrating bioinformatics and machine learning to investigate the mechanisms by which three major respiratory infectious diseases exacerbate heart failure

Yiding Yu, Quancheng Han, Juan Zhang, Jingle Shi, Huajing Yuan, Yitao Xue and Yan Li

Sci Rep, 2025, 15
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Transcriptome analysis reveals the regulatory effects of Bacillus amyloliquefaciens and Bacillus pumilus on immune and digestive related genes in the spleen of weanling black goats

Nanchi Zhang, Juan Li, Li Wang, Yong Wei, Quzhe Emu, Feng Xu and Lin Zhang

Funct Integr Genomics, 2023, 23
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Conserved immunomodulatory transcriptional networks underlie antipsychotic-induced weight gain

Rizaldy C. Zapata, Besma S. Chaudry, Mariela Lopez Valencia, Dinghong Zhang, Scott A. Ochsner, Neil J. McKenna and Olivia Osborn

Transl Psychiatry, 2021, 11
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Increased viperin expression induced by avian infectious bronchitis virus inhibits viral replication by restricting cholesterol synthesis: an in vitro study

Yu Zhang, Tao-Ni Zhang, Yan-Peng Lu, Li-Na Ren, Sheng-Ting Chen, Ling Liu, Lan-Ping Wei, Ji-Ming Chen, Jian-Ni Huang and Mei-Lan Mo

Vet Res, 2024, 55
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Therapeutic effect of Bacillus Calmette–Guerin polysaccharide nucleic acid on mast cell at the transcriptional level

Siyu Yan, Runqiu Liu, Manyun Mao, Zhaoqian Liu, Wei Zhang, Yi Zhang, Jie Li, Cong Peng and Xiang Chen

PeerJ, 2019, 7, e7404
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Viperin, through its radical‐SAM activity, depletes cellular nucleotide pools and interferes with mitochondrial metabolism to inhibit viral replication

Kourosh H. Ebrahimi, Duncan Howie, Jack S. Rowbotham, James McCullagh, Fraser A. Armstrong and William S. James

FEBS Letters, 2020, 594, 1624
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Teleost TRAF7, a protein functions in the host antiviral responses via NF-κB and IRF3/7 mediated signaling

Peng Tian Li, Ying Li, Ying Chen, Jia Xi Zhang, Zi Hao Luo, Yi Fan Zhang, Jing Jiang, Yi Lei Wang, Zi Ping Zhang, Yong Hua Jiang and Peng Fei Zou

Front. Mar. Sci., 2023, 10
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Recent progress in radical SAM enzymes: New reactions and mechanisms

Ning Zhi, Hongji Zhu, Jianjun Qiao and Min Dong

Chin. Sci. Bull., 2022, 67, 1806
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Emerging role of mitoNEET as mitochondrial sensor of hypoxia

Nghi Thao Hoang and Kourosh Honarmand Ebrahimi

J Biol Inorg Chem, 2026
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Molecular and functional characterization of Viperin in large yellow croaker (Larimichthys crocea)

Wen Luo, Hongling Wu, Ying Huang, Kun Ye, Wenzheng Zou and Fang Han

Fish & Shellfish Immunology, 2025, 165, 110498
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Activation of the RSAD2-YTHDF1 axis in smooth muscle causes inflammatory bowel disease via intercellular mitochondrial transfer

Wen-Di Zhang, Dan-Dan Zhang, Xu Wang, Chen-Yang Li, Fan-Qin Li, Xin-Long Liu, Shi-Zhen Zhang, Wei Sun, Li-Jing Li, Han-Bing Wang, Peng Kong, Xiao-Qin Liu, De-Min Liu, Xiao-Lan Zhang, Ya-Bin Liu and Mei Han

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CSF3 enhances the innate immune responses to ALV-J infections via NF-κB and interferon pathways

Junliang Xia, Weiding Chen, Chengxun Xu, Meihuizi Wang, Guodong Mo and Xiquan Zhang

Poultry Science, 2025, 104, 105648
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The impact of indole-3-lactic acid on immature intestinal innate immunity and development: a transcriptomic analysis

Wuyang Huang, Ky Young Cho, Di Meng and W. Allan Walker

Sci Rep, 2021, 11
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Comparative transcriptomics and virtual screening reveal druggable targets and phytochemicals for atopic dermatitis, psoriasis, and vitiligo

Purvi Malhotra, Aaryan Jaitly, Hargunjeet Kaur, Fernando Berton Zanchi, Mujtaba Husaini, Jessica Dhillon, Ravi Sabharwal, Rishika Gautam, Sandeep Saini and Chander Jyoti Thakur

In Silico Research in Biomedicine, 2026, 2, 100181
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Interferon‐stimulated gene products as regulators of central carbon metabolism

Kourosh H. Ebrahimi, Javier Gilbert‐Jaramillo, William S. James and James S.O. McCullagh

The FEBS Journal, 2021, 288, 3715
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Identification of key molecules in COVID-19 patients significantly correlated with clinical outcomes by analyzing transcriptomic data

Zehua Dong, Qiyu Yan, Wenxiu Cao, Zhixian Liu and Xiaosheng Wang

Front. Immunol., 2022, 13
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Regulatory mechanism of viperin in the interferon signaling pathway of large yellow croaker: Characterization of the promoter region

Wen Luo, Hongling Wu, Ying Huang, Wenzheng Zou and Fang Han

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2025, 279, 111115
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Radical-SAM dependent nucleotide dehydratase (SAND), rectification of the names of an ancient iron-sulfur enzyme using NC-IUBMB recommendations

Yuxuan Ji, Li Wei, Anqi Da, Holger Stark, Peter-Leon Hagedoorn, Simone Ciofi-Baffoni, Sally A. Cowley, Ricardo O. Louro, Smilja Todorovic, Maria Andrea Mroginski, Yvain Nicolet, Maxie M. Roessler, Nick E. Le Brun, Mario Piccioli, William S. James, Wilfred R. Hagen and Kourosh H. Ebrahimi

Front. Mol. Biosci., 2022, 9
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Elevated temperatures reduce population‐specific transcriptional plasticity in developing lake sturgeon (Acipenser fulvescens)

William S. Bugg, Matt J. Thorstensen, Katie E. Marshall, W. Gary Anderson and Ken M. Jeffries

Molecular Ecology, 2023, 32, 4044
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