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A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX

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Lab Chip, 2018, 18, 2614
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A multi-throughput multi-organ-on-a-chip system on a plate formatted pneumatic pressure-driven medium circulation platform

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Lab Chip, 2018, 18, 115
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Applications of tumor chip technology

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Lab Chip, 2018, 18, 2893
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Microfluidic organ-on-a-chip models for the gut–liver axis: from structural mimicry to functional insights

Wanlin Hu, Yushen Wang, Junlei Han, Wenhong Zhang, Jun Chen, Xinyu Li and Li Wang

Biomater. Sci., 2025, 13, 1624
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Recent advances in an organ-on-a-chip: biomarker analysis and applications

Xian Li and Tian Tian

Anal. Methods, 2018, 10, 3122
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Bone-chip system to monitor osteogenic differentiation using optical imaging

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Navigating ethical challenges in the development and translation of biomaterials research

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Organs-on-a-chip: Current applications and consideration points for in vitro ADME-Tox studies

Seiichi Ishida

Drug Metabolism and Pharmacokinetics, 2018, 33, 49
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The solitary nucleus connectivity to key autonomic regions in humans

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Cardiovascular disease models: A game changing paradigm in drug discovery and screening

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Biomaterials, 2019, 198, 3
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Machine Learning‐Enabled Correlation and Modeling of Multimodal Response of Thin Film to Environment on Macro and Nanoscale Using “Lab‐on‐a‐Crystal”

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Adv Funct Materials, 2020, 30
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Human organotypic bioconstructs from organ-on-chip devices for human-predictive biological insights on drug candidates

Icilio Cavero, Jean-Michel Guillon and Henry H Holzgrefe

Expert Opinion on Drug Safety, 2019, 18, 651
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Multistep Fluidic Control Network toward the Automated Generation of Organ-on-a-Chip

Hsin-Lin Hsieh, Pulak Nath and Jen-Huang Huang

ACS Biomater. Sci. Eng., 2019, 5, 4852
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Frontiers in Microfluidics, a Teaching Resource Review

Jack Merrin

Bioengineering, 2019, 6, 109
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Human Organs‐on‐Chips: A Review of the State‐of‐the‐Art, Current Prospects, and Future Challenges

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Advanced Biology, 2022, 6
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A Makerspace for Life Support Systems in Space

Jessica E. Snyder, David Walsh, Peter A. Carr and Lynn J. Rothschild

Trends in Biotechnology, 2019, 37, 1164
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Revolutionizing drug evaluation system with organ-on-a-chip and artificial intelligence: A critical review

Ranjit Barua, Deepanjan Das and Nirmalendu Biswas

Biomicrofluidics, 2025, 19
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Surface-Acoustic-Wave (SAW)-Driven Device for Dynamic Cell Cultures

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Anal. Chem., 2018, 90, 7450
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Reverse-engineering organogenesis through feedback loops between model systems

Cody Narciso and Jeremiah Zartman

Current Opinion in Biotechnology, 2018, 52, 1
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Basement membrane properties and their recapitulation in organ-on-chip applications

Golestan Salimbeigi, Nihal E. Vrana, Amir M. Ghaemmaghami, Pinar Y. Huri and Garrett B. McGuinness

Materials Today Bio, 2022, 15, 100301
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Organ-on-Chip Technology for Aerobic Intestinal Host – Anaerobic Microbiota Research

Elsbeth G.B.M. Bossink, Loes I. Segerink and Mathieu Odijk

Organs-on-a-Chip, 2022, 4, 100013
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Integrated brain on a chip and automated organ‐on‐chips systems

Zhe Li, Yimeng Zhao, Xuefei Lv and Yulin Deng

Interdisciplinary Medicine, 2023, 1
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From organotypic culture to body‐on‐a‐chip: A neuroendocrine perspective

Luke A. Schwerdtfeger and Stuart A. Tobet

J Neuroendocrinology, 2019, 31
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Reproducibility, relevance and reliability as barriers to efficient and credible biomedical technology translation

Ulrich Dirnagl, Georg N. Duda, David W. Grainger, Petra Reinke and Ronenn Roubenoff

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Computational Simulations in Advanced Microfluidic Devices: A Review

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Micromachines, 2021, 12, 1149
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Evaluation of toxicity of heated tobacco products aerosol and cigarette smoke to BEAS-2B cells based on 3D biomimetic chip model

Hongjuan Wang, Fengjun Lu, Yushan Tian, Sen Zhang, Shulei Han, Yaning Fu, Jun Li, Pengxia Feng, Zhihao Shi, Huan Chen and Hongwei Hou

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Strategy advancements in placental pharmacokinetics: from in vitro experiments to in silico prediction

Zhimin Li, Yue Wu, Siyu Zeng, Fei Wang, Jiao Zhang, Shiran Li, Yong Yang and Yujie Yang

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Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design

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Pharmaceutics, 2023, 15, 1916
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Application of Micro-Engineered Kidney, Liver, and Respiratory System Models to Accelerate Preclinical Drug Testing and Development

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Bioengineering, 2022, 9, 150
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Glass-based organ-on-a-chip device for restricting small molecular absorption

Hirotada Hirama, Taku Satoh, Shinji Sugiura, Kazumi Shin, Reiko Onuki-Nagasaki, Toshiyuki Kanamori and Tomoya Inoue

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A comparative study of tumour-on-chip models with patient-derived xenografts for predicting chemotherapy efficacy in colorectal cancer patients

Louis Jun Ye Ong, Shumei Chia, Stephen Qi Rong Wong, Xiaoqian Zhang, Huiwen Chua, Jia Min Loo, Wei Yong Chua, Clarinda Chua, Emile Tan, Hannes Hentze, Iain Beehuat Tan, Ramanuj DasGupta and Yi-Chin Toh

Front. Bioeng. Biotechnol., 2022, 10
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A comprehensive overview of advanced dynamic in vitro intestinal and hepatic cell culture models

Filipa Leal, Scarlett Zeiringer, Ramona Jeitler, Pedro F. Costa and Eva Roblegg

Tissue Barriers, 2024, 12
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Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles

Attila A. Seyhan

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Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery

Tanvir Ahmed

Biosensors and Bioelectronics: X, 2022, 11, 100194
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Investigation of absorption, metabolism and toxicity of ginsenosides compound K based on human organ chips

Dongdong Liu, Siming Jiao, Jinhua Wei, Xuebing Zhang, Yuxin Pei, Zhichao Pei, Jianjun Li and Yuguang Du

International Journal of Pharmaceutics, 2020, 587, 119669
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Peripheral nerve sheath tumors-on-a-chip: Next-generation platforms for mechanistic and therapeutic studies

William H. Delaney, Sara A. Faulkner, Wilbur A. Lam, Nicholas M. Boulis, Yongzhi Qiu and Kecheng Lei

Materials Today Advances, 2026, 30, 100770
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Development of a Bacterial Macroarray for the Rapid Screening of Targeted Antibody-Secreted Hybridomas

Jie Li, XuZhao Zhai, Chengchao Ding, Yali Liu, Qingli Dong, Dongpo Xu, Xiang Wang, Jingxuan Qiu, Qi Zhang, Jing Pan and Qing Liu

SLAS Discovery, 2019, 24, 190
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Multi-Organs-on-Chips: Towards Long-Term Biomedical Investigations

Yi Zhao, Ranjith Kumar Kankala, Shi-Bin Wang and Ai-Zheng Chen

Molecules, 2019, 24, 675
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Pharmaceutical technologies with potential application to insecticide discovery†

Keith D Wing

Pest Management Science, 2021, 77, 3617
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Probing prodrug metabolism and reciprocal toxicity with an integrated and humanized multi-tissue organ-on-a-chip platform

Shiny Amala Priya Rajan, Julio Aleman, MeiMei Wan, Nima Pourhabibi Zarandi, Goodwell Nzou, Sean Murphy, Colin E. Bishop, Hooman Sadri-Ardekani, Tom Shupe, Anthony Atala, Adam R. Hall and Aleksander Skardal

Acta Biomaterialia, 2020, 106, 124
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Microfluidic trends in drug screening and drug delivery

Jianguo Feng, Jiri Neuzil, Andreas Manz, Ciprian Iliescu and Pavel Neuzil

TrAC Trends in Analytical Chemistry, 2023, 158, 116821
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