This review summarizes the advances of gem-F2CPs as fluoroallylic synthons in transition metal-catalysed ring-opening/cross-coupling reactions via single, double or no C-F bond cleavage on the last two years.
This feature article summarizes our efforts towards developing Rh-catalyzed reactions of gem-difluorinated cyclopropanes, briefly discussing the design, selectivity, mechanisms and future research prospects.
Vascular adhesion protein-1 (VAP-1), also known as copper-containing amine oxidase 3 (AOC3), is an enzyme implicated in the pathogenesis of various diseases.
A straightforward protocol for the synthesis of 3-fluoroallyl alcohols via fluorine-hydrogen bonding promoted gold catalyzed hydrofluorination using Et3N·3HF under acidic additive-free conditions has been developed.
A diverse series of two- or three-component-derived 2-F,N,S,O-subtituted indolizines was prepared as a new product type for fluorocyclopropane chemistry.