A convenient Cu-catalyzed synthesis of 2-arylquinazolin-4(3H)-one derivatives has been developed using simple starting materials such as 2-nitrobenzonitriles and alcohols under mild conditions.
A facile Ru-catalysed synthesis of 2-arylquinazolin-4(3H)-ones from 2-nitrobenzonitriles and alcohols is described. This method features a broad substrate scope, high yields allowing for convenient and sustainable synthesis.
Diaryl acetylenes undergo spiroannulation with 4-arylquinazolin-2-ones to afford spiro[indene-1,4′-quinazolin]-2′(3′H)-one frameworks. This is the first report on the spiroannulation of 4-arylquinazolin-2-ones with alkynes.
The catalytic aspects of metal complexes of redox non-innocent azo ligands in achieving important and useful chemicals by a hassle-free and economical technique have been presented with in-depth mechanistic explications.
A visible-light-promoted metal-free radical cascade cyclization reaction has been developed with 3-allyl-2-arylquinazolinones as a new class of radical acceptor.