Muhammad Badrul Huda, Unang Supratman and Yudha P. Budiman
RSC Adv., 2026,16, 7496-7521
Abstract
Synthetic methods for the fluorination of terpenoids have enabled the development of fluorinated terpenoids as important pharmaceuticals.
Monika Bilska-Markowska, Tomasz Cytlak and Marcin Kaźmierczak
Chem. Commun., 2025,61, 785-802
Abstract
Trifluoromethylated lactams combine the CF3 group’s unique electronic properties with the biological potential of cyclic amides, offering opportunities for novel syntheses and exploration of their promising medical applications.
Chi Gao, Yang Liu, Cheng-Sheng Li, He Guo, Sheng-Han Wang, Cong Xu and Mang Wang
Chem. Sci., 2025,16, 8561-8568
Abstract
Here we report an unprecedented O-trifluoromethylation of ketones using chloro(phenyl)trifluoromethyl-λ3-iodane (CPTFI).
Yaopeng Liu, Qingyu Tian, Jin Ge, Xi Wu, Zhenghao Li and Guolin Cheng
Org. Biomol. Chem., 2024,22, 6246-6276
Abstract
Recent advances in the preparation of trifluoromethyl-containing heterocyclics via trifluoromethyl building block strategies over the period from 2019 to the present are systematically summarized and discussed.
Yuyu Lv, Zhoubin Deng, Zhijun Zhu, Xiaopeng Hai, Junjiao Wang, Ke-Hu Wang, Danfeng Huang and Yulai Hu
Org. Biomol. Chem., 2025,23, 9658-9667
Abstract
3,3-Spirocyclic 2-trifluoromethylindolines have been synthesized via a visible-light-induced cascade radical trifluoromethylation/cyclization/dearomatization reaction between 3-substituted indoles and CF3Br.