We characterize an ionic cocrystal of ponatinib HCl using X-ray diffraction and solid-state NMR. Multinuclear NMR, with ultra-high fields up to 35.2 T, lays the groundwork for characterization of complex crystals in the absence of diffraction data.
Hydrolysis-activated in situ pore engineering in zeolites: NH4F in methanol as a deceptively inert agent for a Trojan horse-like introduction and activation.
Mechanochemistry was used to synthesize ionic cocrystals of phenothiazine drugs that were characterized by 35Cl solid-state NMR and DFT calculations.
We present the rapid and robust acquisition of 103Rh solid-state NMR spectra for a series of inorganic and organometallic compounds. Relativistic DFT calculations provide relationships between 103Rh chemical shift tensors, structure, and bonding.
Competitive and stability milling reactions, along with 35Cl solid-state NMR and powder X-ray diffraction measurements, are used to assess coformer affinity and cocrystal stability for a series of fluoxetine HCl cocrystals.