Indole-3-butyric acids can be oxidized to lactones via 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) catalysis with MnO2 as the stoichiometric oxidant.
In this review, we have showcased the diverse aspects of transition-metal catalysis, biocatalysis, and photocatalytic C(sp3)–H bond functionalization to access lactones and lactams.
Oxepanes and thiepanes are central motifs and tenants of many biologically important molecules. This comprehensive review covers synthetic methods for their preparation and use in the total synthesis of polyoxygenated oxepane natural products.
Direct alteration of unactivated C–H bonds of organic building blocks.
A cost-effective, practical, straightforward and scalable synthesis of α-pyrones via base- and sulfur-promoted annulation of phenylacetates and chalcones is reported.