Compartmentalized drug localization studies in extracellular vesicles for anticancer therapy

Arunkumar Pitchaimani, Miguel Ferreira, Annalisa Palange, Martina Pannuzzo, Claudia De Mei, Raffaele Spano, Roberto Marotta, Beatriz Pelacho, Felipe Prosper and Paolo Decuzzi

Nanoscale Adv., 2023, 5, 6830
DOI: 10.1039/D3NA00207A

Effects of morphology and size of nanoscale drug carriers on cellular uptake and internalization process: a review

Wenjie Zhang, Reza Taheri-Ledari, Fatemeh Ganjali, Seyedeh Shadi Mirmohammadi, Fateme Sadat Qazi, Mahdi Saeidirad, Amir KashtiAray, Simindokht Zarei-Shokat, Ye Tian and Ali Maleki

RSC Adv., 2023, 13, 80
DOI: 10.1039/D2RA06888E

Development of in vitro model of exosome transport in microfluidic gut-brain axis-on-a-chip

Gwang Myeong Seo, Hongki Lee, Yeon Jae Kang, Donghyun Kim and Jong Hwan Sung

Lab Chip, 2024, 24, 4581
DOI: 10.1039/D4LC00490F

Application of nanotechnology in bladder cancer diagnosis and therapeutic drug delivery

Hang-zhuo Li, Jian Zhu, Guo-jun Weng, Jian-jun Li, Lei Li and Jun-wu Zhao

J. Mater. Chem. B, 2023, 11, 8368
DOI: 10.1039/D3TB01323E

A microfluidics vapor-membrane-valve generated by laser irradiation on carbon nanocoils

Yuli Liu, Chengwei Li, Ming Zhao, Jian Shen and Lujun Pan

RSC Adv., 2023, 13, 20248
DOI: 10.1039/D3RA01148H

Characteristics, Classification, and Application of Stem Cells Derived from Human Teeth

Tong Lei, Xiaoshuang Zhang, Hongwu Du and Andrea Ballini

Stem Cells International, 2021, 2021, 1
DOI: 10.1155/2021/8886854

microRNAs‐based diagnostic and therapeutic applications in liver fibrosis

Xingtao Zhao, Xinyan Xue, Zhifu Cui, Felix Kwame Amevor, Yan Wan, Ke Fu, Cheng Wang, Cheng Peng and Yunxia Li

WIREs RNA, 2023, 14
DOI: 10.1002/wrna.1773

Extracellular vesicles as vital players in drug delivery: a focus on clinical disease treatment

Tiangang Chen, Dan Chen, Wanting Su, Jianlan Liang, Xiangning Liu and Mingxiang Cai

Front. Bioeng. Biotechnol., 2025, 13
DOI: 10.3389/fbioe.2025.1600227

Advanced materials for non-alcoholic fatty liver disease and cardiovascular disease comorbidity therapeutics

Jianrong Na, Lei Huang, Lijuan Wang, Yue Ni, Yisheng Chen, Qiancheng Luo and Yan Li

Biomaterials, 2026, 333, 124209
DOI: 10.1016/j.biomaterials.2026.124209

Recent advances in extracellular vesicle-based organic nanotherapeutic drugs for precision cancer therapy

Van-Nghia Nguyen, Thuy Nguyen Thi Dao, Moonyeon Cho, Hyunsun Jeong, Minh-Tri Nguyen-Le, Yong Shin and Juyoung Yoon

Coordination Chemistry Reviews, 2023, 479, 215006
DOI: 10.1016/j.ccr.2022.215006

Exosome as a stable carrier for anti-inflammatory phenylpropanoid metabolites: a proof-of-concept study

Shirali Patel, Neeraja Revi, Suridh Chakravarty, Aleksandra Gurgul, Yahya Najjar, Chun-Tao Che, Katherine Mary Warpeha and Divya Bijukumar

Biomed. Mater., 2025, 20, 045023
DOI: 10.1088/1748-605X/ade7e3

Current Understanding of Therapeutic and Diagnostic Applications of Exosomes in Pancreatic Cancer

Neda Shakerian, Aida Tafazoli, Amir Razavinia, Zahra Sadrzadeh Aghajani, Nikoo Bana, Maysam Mard-Soltani, Bahman Khalesi, Zahra Sadat Hashemi and Saeed Khalili

Pancreas, 2025, 54, e255
DOI: 10.1097/MPA.0000000000002414

Electrostatic Gelatin Nanoparticles for Biotherapeutic Delivery

Connor Tobo, Avantika Jain, Madhushika Elabada Gamage, Paul Jelliss and Koyal Garg

Gels, 2024, 10, 757
DOI: 10.3390/gels10120757

Mesenchymal stem cell-derived exosomes: a potential cell-free therapy for orthodontic tooth stability management

Boyuan Peng, Lianhao Wang, Guangli Han and Yong Cheng

Stem Cell Res Ther, 2024, 15
DOI: 10.1186/s13287-024-03962-3

Multifunctional nanoparticle for cancer therapy

Yan Gao, Kaiyu Wang, Jin Zhang, Xingmei Duan, Qiu Sun and Ke Men

MedComm, 2023, 4
DOI: 10.1002/mco2.187

Exosomes for skin treatment: Therapeutic and cosmetic applications

Harsha Sreeraj, R. AnuKiruthika, K.S. Tamilselvi and D. Subha

Nano TransMed, 2024, 3, 100048
DOI: 10.1016/j.ntm.2024.100048

Potential of Exosomes as Multifunctional Nanocarriers for Targeted Drug Delivery

Safa Ali Al-Ani, Qiao Ying Lee, Danesha Maheswaran, Yuh Miin Sin, Jian Sheng Loh, Jhi Biau Foo, Sharina Hamzah, Jeck Fei Ng and Li Kar Stella Tan

Mol Biotechnol, 2025, 67, 3391
DOI: 10.1007/s12033-024-01268-6

WITHDRAWN: Engineering Exosomes and Exosome-like Nanovesicles for Improving Targeted Retention

Lanya Li, Fei Wang, Dashuai Zhu, Shiqi Hu, Ke Cheng and Zhenhua Li

Fundamental Research, 2024
DOI: 10.1016/j.fmre.2023.11.024

From hope to healing: Exploring the therapeutic potential of exosomes in spinal cord injury

Nidhi Singh, Lahanya Guha and Hemant Kumar

Extracellular Vesicle, 2024, 3, 100044
DOI: 10.1016/j.vesic.2024.100044

Drug Loading and Functional Efficacy of Cow, Buffalo, and Goat Milk-Derived Exosomes: A Comparative Study

Farhan Ahmed, Mounipriya Tamma, Umamaheswari Pathigadapa, Pallu Reddanna and Vengala Rao Yenuganti

Mol. Pharmaceutics, 2022, 19, 763
DOI: 10.1021/acs.molpharmaceut.1c00182

Stem cell-based therapy for pulmonary fibrosis

Wenzhao Cheng, Yiming Zeng and Dachun Wang

Stem Cell Res Ther, 2022, 13
DOI: 10.1186/s13287-022-03181-8

Recent Advancements on the Use of Exosomes as Drug Carriers for the Treatment of Glioblastoma

Angela Galardi, Alexander De Bethlen, Virginia Di Paolo, Silvia Lampis, Angela Mastronuzzi and Angela Di Giannatale

Life, 2023, 13, 964
DOI: 10.3390/life13040964

The Application of Exosomes From Different Sources Loaded with Natural Small-Molecule Compounds in Disease

Lulu Zhang, Changqi Shi, Lan Yan, Xiaomeng Zhang, Xinyu Ji, Li Li, Xiaojuan He, Yong Tan, Ning Zhao and Cheng Lu

IJN, 2025, Volume 20, 12363
DOI: 10.2147/IJN.S542641

Exosomes: Another intercellular lipometabolic communication mediators in digestive system neoplasms?

Shaodong Li, Ruizhi Dong, Zhenhua Kang, Hucheng Li, Xueliang Wu and Tian Li

Cytokine & Growth Factor Reviews, 2023, 73, 93
DOI: 10.1016/j.cytogfr.2023.06.005

Construction of exosome-loaded LL-37 and its protection against zika virus infection

Chen Wang, Min Li, Xiaohui Xia, Yuxuan Fu, Yi Wang, Wei Xu, Hongqi Wei and Lin Wei

Antiviral Research, 2024, 225, 105855
DOI: 10.1016/j.antiviral.2024.105855

Engineered exosomes: a promising approach for overcoming challenges in pancreatic cancer therapy

Mo Sha, Yang Gao, Xu Yin, Xueyao Li, Caiqi Liu and Shuang Li

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03697-0

Hyper-inflammatory responses in COVID-19 and anti-inflammatory therapeutic approaches

Hojun Choi and Eui-Cheol Shin

BMB Rep, 2022, 55, 11
DOI: 10.5483/BMBRep.2022.55.1.152

Extracellular Vesicle-Based Therapeutic Cargo Delivery for Cancer Therapy

Zhiben Huang, Jiaqing Cheng, Zhimin Deng, Chunjiang Liu, Tianying Huang and Wansong Lin

IJN, 2025, Volume 20, 13007
DOI: 10.2147/IJN.S548006

Exosomes as new generation vehicles for drug delivery systems

N. Dilsiz

Journal of Drug Delivery Science and Technology, 2024, 95, 105562
DOI: 10.1016/j.jddst.2024.105562

Physically engineered extracellular vesicles targeted delivering miR-21-5p to promote renoprotection after renal ischemia-reperfusion injury

Di Wu, Wenjie Ma, Liucheng Wang, Chengcheng Long, Silin Chen, Jingyu Liu, Yiguan Qian, Jun Zhao, Changcheng Zhou and Ruipeng Jia

Materials Today Bio, 2025, 31, 101528
DOI: 10.1016/j.mtbio.2025.101528

Recent updates in nanoscale delivery systems of platinum(IV) antitumor prodrugs

Zhiyuan Zhou, Pengmin Shi, Changli Wang, Yanyan Sun and Chuanzhu Gao

Coordination Chemistry Reviews, 2024, 508, 215774
DOI: 10.1016/j.ccr.2024.215774

Engineered Exosomes Containing Cathelicidin/LL‐37 Exhibit Multiple Biological Functions

Yajuan Su, Navatha Shree Sharma, Johnson V. John, Gitali Ganguli‐Indra, Arup K. Indra, Adrian F. Gombart and Jingwei Xie

Adv Healthcare Materials, 2022, 11
DOI: 10.1002/adhm.202200849

Bioinspired Membrane‐Based Cancer Vaccines for Immunotherapy: Progress and Perspectives

Yanyu Miao, Jianlin Ge, Longyi Zheng and Gang Liu

Small, 2025, 21
DOI: 10.1002/smll.202412679

Celecoxib-loaded mesenchymal stem cell-derived exosomes ameliorate laser-induced choroidal neovascularization in a rabbit model

Shahla Lotfi, Pasha Anvari, Aghdas Ramezani, Pegah Kazemi and Davoud Ahmadvand

Journal of Drug Delivery Science and Technology, 2025, 114, 107514
DOI: 10.1016/j.jddst.2025.107514

Microneedle Patch Loaded with Exosomes Containing MicroRNA‐29b Prevents Cardiac Fibrosis after Myocardial Infarction

Jianping Yuan, Hong Yang, Chunxia Liu, Lianbo Shao, Haixin Zhang, Kunyan Lu, Jingjing Wang, Yuanyuan Wang, Qian Yu, Yanxia Zhang, Yunsheng Yu and Zhenya Shen

Adv Healthcare Materials, 2023, 12
DOI: 10.1002/adhm.202202959

Intranasal Administration of Self-Oriented Nanocarriers Based on Therapeutic Exosomes for Synergistic Treatment of Parkinson’s Disease

Huan Peng, Yan Li, Weihong Ji, Ruichen Zhao, Zhiguo Lu, Jie Shen, Yanyue Wu, Jianze Wang, Qiulian Hao, Jingwen Wang, Wenli Wang, Jun Yang and Xin Zhang

ACS Nano, 2022, 16, 869
DOI: 10.1021/acsnano.1c08473

Recent advancements to engineer mesenchymal stem cells and their extracellular vesicles for targeting and destroying tumors

Mohsen Karami Fath, Zahra Moayedi Banan, Reza Barati, Omid Mohammadrezakhani, Aliasghar Ghaderi, Ali Hatami, Shamim Ghiabi, Nazanin Zeidi, Katayoon Asgari, Zahra Payandeh and Ghasem Barati

Progress in Biophysics and Molecular Biology, 2023, 178, 1
DOI: 10.1016/j.pbiomolbio.2023.02.001

Plasma Exosomal LncRNA XIST Impairs CD4+ T Cell Autophagy and Promotes Activation via the miR-98/RICTOR/Akt-mTOR Axis in Systemic Lupus Erythematosus

Li Wang, Fan Lyu, Jun Liang, Xi Chen, Chenghui Zheng, Mingyu Chu, Jinhua Xu and Lin Xie

JIR, 2026, Volume 19, 1
DOI: 10.2147/JIR.S574715

Can Extracellular Vesicles as Drug Delivery Systems Be a Game Changer in Cardiac Disease?

Akihiko Okamura, Yusuke Yoshioka, Yoshihiko Saito and Takahiro Ochiya

Pharm Res, 2023, 40, 889
DOI: 10.1007/s11095-022-03463-z

From Exosome Glycobiology to Exosome Glycotechnology, the Role of Natural Occurring Polysaccharides

Giulia Della Rosa, Clarissa Ruggeri and Alessandra Aloisi

Polysaccharides, 2021, 2, 311
DOI: 10.3390/polysaccharides2020021

Advances in nanomedicines for diagnosis of central nervous system disorders

Xun Zhang, Jie Zhou, Zhongwei Gu, Hu Zhang, Qiyong Gong and Kui Luo

Biomaterials, 2021, 269, 120492
DOI: 10.1016/j.biomaterials.2020.120492

Progress of exosome research in systemic lupus erythematosus

Jie Shen, Mengyu Zhang and Meiyu Peng

Cytokine: X, 2022, 4, 100066
DOI: 10.1016/j.cytox.2022.100066

Exosomes as Crucial Players in Pathogenesis of Systemic Lupus Erythematosus

Yue Fei, Qi Liu, Na Peng, Guocan Yang, Ziwei Shen, Pan Hong, Shengjun Wang, Ke Rui, Dawei Cui and Lihua Duan

Journal of Immunology Research, 2022, 2022, 1
DOI: 10.1155/2022/8286498

The Study of Exosomes-Encapsulated mPEG-PLGA Polymer Drug-Loaded Particles for Targeted Therapy of Liver Cancer

Jiantao Mo, Xuanbo Da, Qiaoxin Li, Jingjing Huang, Le Lu, Hongwei Lu and Rui Liao

Journal of Oncology, 2022, 2022, 1
DOI: 10.1155/2022/4234116

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah and Kristen Dellinger

Advanced Biology, 2025, 9
DOI: 10.1002/adbi.202400623

Role of exosomes in tumour growth, chemoresistance and immunity: state-of-the-art

Seyedeh Maryam Hosseinikhah, Fatemeh Gheybi, Seyedeh Alia Moosavian, Mohammad-Ali Shahbazi, Mahmoud Reza Jaafari, Mika Sillanpää, Prashant Kesharwani, Seyedeh Hoda Alavizadeh and Amirhossein Sahebkar

Journal of Drug Targeting, 2023, 31, 32
DOI: 10.1080/1061186X.2022.2114000

Extracellular vesicle–based drug delivery system boosts phytochemicals’ therapeutic effect for neurodegenerative diseases

Zhenzhu Zhu, Liuyue Liao and Hongzhi Qiao

Acupuncture and Herbal Medicine, 2022, 2, 229
DOI: 10.1097/HM9.0000000000000039

Mmu-miR-25-3p promotes macrophage autophagy by targeting DUSP10 to reduce mycobacteria survival

Wenqi Yuan, Xuehua Zhan, Wei Liu, Rong Ma, Yueyong Zhou, Guangxian Xu and Zhaohui Ge

Front. Cell. Infect. Microbiol., 2023, 13
DOI: 10.3389/fcimb.2023.1120570

Quantitative Biodistribution and Pharmacokinetics Study of GMP-Grade Exosomes Labeled with 89Zr Radioisotope in Mice and Rats

Hojun Choi, Myung-Yoon Kim, Dae-Hwan Kim, Hanoul Yun, Byung-Koo Oh, Su-Bin Kim, In-Ho Song, Hyun-Soo Park, Sang-Eun Kim, Cheolhyoung Park and Chulhee Choi

Pharmaceutics, 2022, 14, 1118
DOI: 10.3390/pharmaceutics14061118

The Current Status and Future Direction of Extracellular Nano-vesicles in the Alleviation of Skin Disorders

Raziyeh Ghorbani, Simzar Hosseinzadeh, Arezo Azari, Niloofar Taghipour, Masoud Soleimani, Azam Rahimpour and Hojjat Allah Abbaszadeh

CSCR, 2024, 19, 351
DOI: 10.2174/1574888X18666230418121053

mRNA vaccines and SiRNAs targeting cancer immunotherapy: challenges and opportunities

Zhen Lv and Yuheng Dai

Discov Onc, 2025, 16
DOI: 10.1007/s12672-025-03070-5

Exosomes as Drug Delivery Systems: Endogenous Nanovehicles for Treatment of Systemic Lupus Erythematosus

Ana Ortega, Olga Martinez-Arroyo, Maria J. Forner and Raquel Cortes

Pharmaceutics, 2020, 13, 3
DOI: 10.3390/pharmaceutics13010003

Effect of Photobiomodulation on Structure and Function of Extracellular Vesicle Secreted from Mesenchymal Stem Cells

Leila Gholami, Khatereh Khorsandi, Vajihe Taghdiri Nooshabadi, Shiva Shahabi, Marzieh Jazaeri, HomaSadat Esfahani, Davood Rabiei Faradonbeh, Ziba Veisi Malekshahi, Zohreh Afsartala and Nesrine Mostafa

Photochem & Photobiology, 2022, 98, 1447
DOI: 10.1111/php.13633

Mesenchymal Stem Extracellular Vesicles in Various Respiratory Diseases: A New Opportunity

Zijun Hu, Lujian Zhu, Yanglin Zhu and Yejin Xu

JIR, 2024, Volume 17, 9041
DOI: 10.2147/JIR.S480345

Advances in Studies on Exosomes and Their Roles in Systemic Lupus Erythematosus

攀吕

ACM, 2022, 12, 11975
DOI: 10.12677/ACM.2022.12121725

Tropoelastin-Pretreated Exosomes from Adipose-Derived Stem Cells Improve the Synthesis of Cartilage Matrix and Alleviate Osteoarthritis

Shuo Meng, Cong Tang, Muhai Deng, Jie Yuan, Yanli Fan, Shasha Gao, Yong Feng, Junjun Yang and Cheng Chen

JFB, 2023, 14, 203
DOI: 10.3390/jfb14040203

Engineered RVG-exosomes-mediated delivery of siRNAs targeting NMDAR alleviates orofacial neuropathic pain by suppressing central sensitivity

Yan-Yan Zhang, Yue-Ling Li, Qin-Xuan Song, Ya-Ting Yi, Yu-Heng Feng, Yi-Ke Li, Cheng Zhou, Chun-Jie Li, Fei Liu and Jie-Fei Shen

The Journal of Pain, 2025, 33, 105457
DOI: 10.1016/j.jpain.2025.105457

Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies

Gangling Xu, Jing Jin, Zhihao Fu, Guangming Wang, Xinhua Lei, Jun Xu and Junzhi Wang

Sig Transduct Target Ther, 2025, 10
DOI: 10.1038/s41392-025-02312-w

Advancements in strategies for overcoming the blood–brain barrier to deliver brain-targeted drugs

Zhichuang Qu, Juan Luo, Zheng Li, Rong Yang, Jiaxi Zhao, Xin Chen, Sixun Yu and Haifeng Shu

Front. Aging Neurosci., 2024, 16
DOI: 10.3389/fnagi.2024.1353003

Nanomedicine and regenerative medicine approaches in osteoarthritis therapy

Ramin Goudarzi, Ahmad Reza Dehpour and Alireza Partoazar

Aging Clin Exp Res, 2022, 34, 2305
DOI: 10.1007/s40520-022-02199-5

Nanomaterials-Based Exosomes for the Diagnostics and Drug Deliveries of Central Nervous System Diseases

Izzati Haizan, Dong Hyeok Park, Min Yu Choi, Hyerim Lee and Jin-Ha Choi

BioChip J, 2023, 17, 293
DOI: 10.1007/s13206-023-00112-4

Bio-Inspired Nanocarriers Derived from Stem Cells and Their Extracellular Vesicles for Targeted Drug Delivery

Munire Abudurexiti, Yue Zhao, Xiaoling Wang, Lu Han, Tianqing Liu, Chengwei Wang and Zhixiang Yuan

Pharmaceutics, 2023, 15, 2011
DOI: 10.3390/pharmaceutics15072011

3D bioprinting of dECM/Gel/QCS/nHAp hybrid scaffolds laden with mesenchymal stem cell-derived exosomes to improve angiogenesis and osteogenesis

Yue Kang, Jie Xu, Ling’ao Meng, Ya Su, Huan Fang, Jiaqi Liu, Yuen Yee Cheng, Daqing Jiang, Yi Nie and Kedong Song

Biofabrication, 2023, 15, 024103
DOI: 10.1088/1758-5090/acb6b8

Exosomes may be the carrier of acupuncture treatment for major depressive disorder

Qin Lyu, Xin Zhou, Liu-Qing Shi, Hai-Yang Chen, Mei Lu, Xian-De Ma and Lu Ren

Front. Behav. Neurosci., 2023, 17
DOI: 10.3389/fnbeh.2023.1107265

Plasma Exosome Analysis for Protein Mutation Identification Using a Combination of Raman Spectroscopy and Deep Learning

Seungmin Kim, Byeong Hyeon Choi, Hyunku Shin, Kihun Kwon, Sung Yong Lee, Hyun Bin Yoon, Hyun Koo Kim and Yeonho Choi

ACS Sens., 2023, 8, 2391
DOI: 10.1021/acssensors.3c00681

Exosome as drug delivery system: Current advancements

Vriti Sharma and Chitrangada Das Mukhopadhyay

Extracellular Vesicle, 2024, 3, 100032
DOI: 10.1016/j.vesic.2023.100032

GSTP1-modified exosomes derived from ADMSCs relieve LPS-induced acute lung injury

Hong Guan, Junkai Du, Xiaoyan Wang, Zhen Zhang, Wanbo Zhou and Feng Wang

Cytotechnology, 2026, 78
DOI: 10.1007/s10616-025-00863-y

Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosis

Duo Wang, Guanhua Qiu, Xiaoqi Zhu, Qin Wang, Chunyan Zhu, Chao Fang, Junjie Liu, Kun Zhang and Yan Liu

J Immunother Cancer, 2023, 11, e006516
DOI: 10.1136/jitc-2022-006516

Exosomes-mediated drug delivery for the treatment of myocardial injury

Jiang Li, Aiqin Lin, Rui Jiang, Pingping Chen, Chengyang Xu and Yuanyuan Hou

Annals of Medicine & Surgery, 2024, 86, 292
DOI: 10.1097/MS9.0000000000001473

Exosome‐Based Therapeutics: A Natural Solution to Overcoming the Blood–Brain Barrier in Neurodegenerative Diseases

Min Sun, Feng Qin, Qian Bu, Yue Zhao, Xiaofeng Yang, Dingwen Zhang and Xiaobo Cen

MedComm, 2025, 6
DOI: 10.1002/mco2.70386

Biodistribution of Exosomes and Engineering Strategies for Targeted Delivery of Therapeutic Exosomes

Hojun Choi, Yoorim Choi, Hwa Young Yim, Amin Mirzaaghasi, Jae-Kwang Yoo and Chulhee Choi

Tissue Eng Regen Med, 2021, 18, 499
DOI: 10.1007/s13770-021-00361-0

A Gut-Brain Axis-on-a-Chip for studying transport across epithelial and endothelial barriers

Min-Hyeok Kim, Donghyun Kim and Jong Hwan Sung

Journal of Industrial and Engineering Chemistry, 2021, 101, 126
DOI: 10.1016/j.jiec.2021.06.021

A methodological primer of extracellular vesicles isolation and characterization via different techniques

Farhang Aliakbari, Noah B Stocek, Maxximuss Cole-André, Janice Gomes, Giovanni Fanchini, Stephen H Pasternak, Gunna Christiansen, Dina Morshedi, Kathryn Volkening and Michael J Strong

Biology Methods and Protocols, 2024, 9
DOI: 10.1093/biomethods/bpae009

Rapid and Widespread Distribution of Intranasal Small Extracellular Vesicles Derived from Mesenchymal Stem Cells throughout the Brain Potentially via the Perivascular Pathway

Weiwei Shen, Tongyao You, Wenqing Xu, Yanan Xie, Yingzhe Wang and Mei Cui

Pharmaceutics, 2023, 15, 2578
DOI: 10.3390/pharmaceutics15112578

Cancer-exocytosed exosomes loaded with bio-assembled AgNCs as smart drug carriers for targeted chemotherapy

Tanziela Tanziela, Sana Shaikh, Fawad ur Rehman, Farouk Semcheddine, Hui Jiang, Zuhong Lu and Xuemei Wang

Chemical Engineering Journal, 2022, 440, 135980
DOI: 10.1016/j.cej.2022.135980

Engineered exosomes loaded with M1–8 peptide for targeted therapy of hepatocellular carcinoma

Rui Deng, Jibin Wu, Baokang Zhu, Gaoqing Song, Tao Zhou, Musheng Yang, Lingling Pan, Jian Wang, Xuan Zou, Ziquan Lv, Xiaobao Jin, Yinghua Xu, Xuemei Lu and Shuiqing Gui

Applied Materials Today, 2024, 37, 102071
DOI: 10.1016/j.apmt.2024.102071

Innovating intervertebral disc degeneration therapy: Harnessing the power of extracellular vesicles

Shanfeng Chen, Yiming Dou, Yiming Zhang, Xun Sun, Xinyu Liu and Qiang Yang

Journal of Orthopaedic Translation, 2025, 50, 44
DOI: 10.1016/j.jot.2024.09.014

Lyophilization of Nanoparticles, Does It Really Work? Overview of the Current Status and Challenges

Matthew S. Gatto and Wided Najahi-Missaoui

IJMS, 2023, 24, 14041
DOI: 10.3390/ijms241814041

Intranasal delivery of cannabidiol-loaded hypoxic exosomes for targeted treatment of methamphetamine addiction via enhanced brain penetration and neuroinflammation modulation

Tianshu Zhang, Xiaodong Li, Yinghua Peng, Cong Lin and Xiaohui Wang

Chinese Chemical Letters, 2026, 37, 111794
DOI: 10.1016/j.cclet.2025.111794

Extracellular vesicles in seminal fluid and effects on male reproduction. An overview in farm animals and pets

Jordi Roca, Heriberto Rodriguez-Martinez, Lorena Padilla, Xiomara Lucas and Isabel Barranco

Animal Reproduction Science, 2022, 246, 106853
DOI: 10.1016/j.anireprosci.2021.106853

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Non-Coding RNA Therapeutic Vehicles in Autoimmune Diseases

Olga Martinez-Arroyo, Ana Ortega, Maria J. Forner and Raquel Cortes

Pharmaceutics, 2022, 14, 733
DOI: 10.3390/pharmaceutics14040733

Immune-Cell-Derived Exosomes for Cancer Therapy

Yongmei Zhao, Tianqing Liu and Mengjiao Zhou

Mol. Pharmaceutics, 2022, 19, 3042
DOI: 10.1021/acs.molpharmaceut.2c00407

Exosome membrane-coated nanosystems: Exploring biomedical applications in cancer diagnosis and therapy

Minmin Shao, Daniela Lopes, Joana Lopes, Satar Yousefiasl, Ana Macário-Soares, Diana Peixoto, Inês Ferreira-Faria, Francisco Veiga, João Conde, Yi Huang, Xianfeng Chen, Ana Cláudia Paiva-Santos and Pooyan Makvandi

Matter, 2023, 6, 761
DOI: 10.1016/j.matt.2023.01.012

Synergistic effect of human uterine cervical mesenchymal stem cell secretome and paclitaxel on triple negative breast cancer

Noemi Eiro, Maria Fraile, Sara Escudero-Cernuda, Juan Sendon-Lago, Luis O. Gonzalez, Maria Luisa Fernandez-Sánchez and Francisco J. Vizoso

Stem Cell Res Ther, 2024, 15
DOI: 10.1186/s13287-024-03717-0

Mmu-let-7a-5p inhibits macrophage apoptosis by targeting CASP3 to increase bacterial load and facilities mycobacterium survival

Xuehua Zhan, Wenqi Yuan, Rong Ma, Yueyong Zhou, Guangxian Xu, Zhaohui Ge and Francesco Sessa

PLoS ONE, 2024, 19, e0308095
DOI: 10.1371/journal.pone.0308095

Cell-free protein synthesis and vesicle systems for programmable therapeutic manufacturing and delivery

Wonhee Kim, Jinjoo Han, Shraddha Chauhan and Jeong Wook Lee

J Biol Eng, 2025, 19
DOI: 10.1186/s13036-025-00523-x

Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis

Xiao Lu, Guangyu Xu, Zhidi Lin, Fei Zou, Siyang Liu, Yuxuan Zhang, Wei Fu, Jianyuan Jiang, Xiaosheng Ma and Jian Song

Biomater Res, 2023, 27
DOI: 10.1186/s40824-023-00339-0

Application and Potential of Local Drug Delivery Systems for Antibacterial Treatment of Periodontitis

Xinchao Wang, Fengli Wu, Jia Liu, Xingqi Hong and Shujun Dong

IJMS, 2026, 27, 2983
DOI: 10.3390/ijms27072983

Examining the Synergic Effect of Exosomes Derived from Mouse Mesenchymal Stem Cells and Low-frequency Electromagnetic Field on Chondrogenic Differentiation

Maryam Lotfi, Javad Baharara, Khadije Nejad Shahrokhabadi and Pejman Khorshid

CSCR, 2025, 20, 336
DOI: 10.2174/011574888X314834240628110545

Therapeutic and Diagnostic Potential of Exosomes as Drug Delivery Systems in Brain Cancer

Dimitrios I. Avgoulas, Konstantinos S. Tasioulis, Rigini M. Papi and Anastasia A. Pantazaki

Pharmaceutics, 2023, 15, 1439
DOI: 10.3390/pharmaceutics15051439

Membrane Fusion Liposome-Mediated Ferroptosis Explosion for Enhanced Cancer Therapy

Fanhui Kong, Qi Lei, Yi Ma, Peiying He, Guansheng Zheng, Yue Xu, Junda Huang, C. Jeffrey Brinker, Kaisheng Liu and Wei Zhu

Chem. Mater., 2023, 35, 4731
DOI: 10.1021/acs.chemmater.3c00444

The potential roles of exosomal noncoding RNAs in osteosarcoma

Shenglong Li and Xiaohong Wang

Journal Cellular Physiology, 2021, 236, 3354
DOI: 10.1002/jcp.30101

Exosomes as Naturally Occurring Vehicles for Delivery of Biopharmaceuticals: Insights from Drug Delivery to Clinical Perspectives

Arun Butreddy, Nagavendra Kommineni and Narendar Dudhipala

Nanomaterials, 2021, 11, 1481
DOI: 10.3390/nano11061481

Nanomaterial-based encapsulation of biochemicals for targeted sepsis therapy

Zhiwei Li, Bin Luo, Yisheng Chen, Lingling Wang, Yezi Liu, Jintong Jia, Mengsi Chen, Shuting Yang, Haojun Shi, Lihua Dai, Lei Huang, Changmin Wang and Jia Liu

Materials Today Bio, 2025, 33, 102054
DOI: 10.1016/j.mtbio.2025.102054

Recent Insights into Organoid-Derived Extracellular Vesicles and Their Biomedical Applications

Ahmed Abdal Dayem, Yeonjoo Kwak, Hyemin Jeun and Ssang-Goo Cho

JPM, 2025, 15, 492
DOI: 10.3390/jpm15100492

Nanomedicines Reshape the Tumor Microenvironment: Multidimensional Strategies from Modulating “Barriers” to Metabolic Intervention

Xinming Zhao, Dequan Liu, Guandu Li, Wenfei Xu and Guangzhen Wu

IJN, 2026, Volume 21, 1
DOI: 10.2147/IJN.S570411

Exosome-Integrated Hydrogels for Bone Tissue Engineering

Hee Sook Hwang and Chung-Sung Lee

Gels, 2024, 10, 762
DOI: 10.3390/gels10120762

The exosome: a review of current therapeutic roles and capabilities in human reproduction

Marko Dimik, Pevindu Abeysinghe, Jayden Logan and Murray Mitchell

Drug Deliv. and Transl. Res., 2023, 13, 473
DOI: 10.1007/s13346-022-01225-3

Dual-Drug Delivery by Anisotropic and Uniform Hybrid Nanostructures: A Comparative Study of the Function and Substrate–Drug Interaction Properties

Delaram Kargari Aghmiouni and Sepideh Khoee

Pharmaceutics, 2023, 15, 1214
DOI: 10.3390/pharmaceutics15041214

Engineered bone marrow mesenchymal stem cell-derived exosomes loaded with miR302 through the cardiomyocyte specific peptide can reduce myocardial ischemia and reperfusion (I/R) injury

Jianjun Gu, Jia You, Hao Liang, Jiacai Zhan, Xiang Gu and Ye Zhu

J Transl Med, 2024, 22
DOI: 10.1186/s12967-024-04981-7

Chitosan-based biomaterials for bone tissue engineering

Youbin Li, Xudong Li, Liwei Zhu, Tengyue Liu and Lanfeng Huang

International Journal of Biological Macromolecules, 2025, 304, 140923
DOI: 10.1016/j.ijbiomac.2025.140923

The multifaceted role of extracellular vesicles in prostate cancer-a review

Divya Prakash Jain, Yirivinti Hayagreeva Dinakar, Hitesh Kumar, Rupshee Jain and Vikas Jain

Cancer Drug Resist, 2023, 481
DOI: 10.20517/cdr.2023.17

Effect of the Application of Exosome on Gastric Cancer

Jing Peng, Yiwen Wu, Sijun Deng, Pu Cao, Wei Yang, Tingyi Gong, Xiaoyong Lei and Xiaoyan Yang

CCHTS, 2023, 26, 2267
DOI: 10.2174/1386207326666230213141627

The physiological functions and therapeutic potential of exosomes during the development and treatment of polycystic ovary syndrome

Zhenghong Zhang, Congjian Shi and Zhengchao Wang

Front. Physiol., 2023, 14
DOI: 10.3389/fphys.2023.1279469

Utilizing exosomes as sparking clinical biomarkers and therapeutic response in acute myeloid leukemia

Wandi Wang, Xiaofang Wu, Jiamian Zheng, Ran Yin, Yangqiu Li, Xiuli Wu, Ling Xu and Zhenyi Jin

Front. Immunol., 2024, 14
DOI: 10.3389/fimmu.2023.1315453

Different origin-derived exosomes and their clinical advantages in cancer therapy

Xiaoyan Jin, Jing Zhang, Yufu Zhang, Jing He, Mingming Wang, Yu Hei, Shutong Guo, Xiangrong Xu and Yusi Liu

Front. Immunol., 2024, 15
DOI: 10.3389/fimmu.2024.1401852

Exosomes repairment for sciatic nerve injury: a cell-free therapy

Guang-Da Xin, Xue-Yan Liu, Xiao-Di Fan and Guan-Jie Zhao

Stem Cell Res Ther, 2024, 15
DOI: 10.1186/s13287-024-03837-7

Advances and prospects of microenvironment-targeted nanotherapeutics for ulcerative colitis: evolving paradigms in the precision gut microenvironment

Hongji Lu, Wujing Zhang, Zhibin Wu, Yuzhi Peng, Fangfang Liu, Sheng Gao and Li Deng

International Journal of Pharmaceutics, 2026, 690, 126546
DOI: 10.1016/j.ijpharm.2025.126546

Engineered Exosome for Drug Delivery: Recent Development and Clinical Applications

Jiaqi Tian, Zhengpu Han, Dandan Song, Yanjie Peng, Min Xiong, Zhen Chen, Shuyin Duan and Lin Zhang

IJN, 2023, Volume 18, 7923
DOI: 10.2147/IJN.S444582

Nature-inspired dynamic gene-loaded nanoassemblies for the treatment of brain diseases

Weihong Ji, Yan Li, Huan Peng, Ruichen Zhao and Xin Zhang

Advanced Drug Delivery Reviews, 2022, 180, 114029
DOI: 10.1016/j.addr.2021.114029

Mesenchymal stem cell-derived exosomes as a new therapeutic strategy in the brain tumors

Elham Ghasempour, Shilan Hesami, Elaheh Movahed, Saeed Heidari keshel and Mohammad Doroudian

Stem Cell Res Ther, 2022, 13
DOI: 10.1186/s13287-022-03212-4

Engineering exosomes and exosome-like nanovesicles for improving tissue targeting and retention

Lanya Li, Fei Wang, Dashuai Zhu, Shiqi Hu, Ke Cheng and Zhenhua Li

Fundamental Research, 2025, 5, 851
DOI: 10.1016/j.fmre.2024.03.025

New Developments in Exosomal lncRNAs in Cardiovascular Diseases

Zhu Yuan and Weiqiang Huang

Front. Cardiovasc. Med., 2021, 8
DOI: 10.3389/fcvm.2021.709169

Small extracellular vesicles derived from human mesenchymal stem cells prevent Th17-dominant neutrophilic airway inflammation via immunoregulation on Th17 cells

Bi-Xin He, Shu-Bing Fang, Ying-Chun Xie, Dong-Xiao Lou, Zi-Cong Wu, Chan-Gu Li, Xiao-Qing Liu, Zhi-Rou Zhou, Long-Xin Huang, Tian Tian, De-Hua Chen and Qing-Ling Fu

International Immunopharmacology, 2024, 133, 112126
DOI: 10.1016/j.intimp.2024.112126

Brusatol Inhibits Proliferation and Invasion of Glioblastoma by Down-Regulating the Expression of ECM1

Zhang’an Dai, Lin Cai, Yingyu Chen, Silu Wang, Qian Zhang, Chengde Wang, Ming Tu, Zhangzhang Zhu, Qun Li and Xianghe Lu

Front. Pharmacol., 2021, 12
DOI: 10.3389/fphar.2021.775680

Targeted therapy using engineered extracellular vesicles: principles and strategies for membrane modification

Qisong Liu, Defeng Li, Xiaohua Pan and Yujie Liang

J Nanobiotechnol, 2023, 21
DOI: 10.1186/s12951-023-02081-0

Cross-Scale Integration of Nano-Sized Extracellular Vesicle-Based Biomarker and Radiomics Features for Predicting Suspected Sub-Solid Pulmonary Nodules

Nishant Patel, Wenwen Xu, Yuxia Deng, Jiyang Jin and Haijun Zhang

j biomed nanotechnol, 2021, 17, 1109
DOI: 10.1166/jbn.2021.3097

Cellular nanovesicles for therapeutic immunomodulation: A perspective on engineering strategies and new advances

Endong Zhang, Philana Phan and Zongmin Zhao

Acta Pharmaceutica Sinica B, 2023, 13, 1789
DOI: 10.1016/j.apsb.2022.08.020

Exosomes of immune cell origin and their therapeutic potential for tumors

Hongru Ai, Yitan Zou, Xinya Zheng, Guangyao Li, Changhai Lei, Wenyan Fu and Shi Hu

VIEW, 2024, 5
DOI: 10.1002/VIW.20240029

Exosome-based therapy for spinal cord injury: a narrative review

Xiaowei Zha

Advanced Technology in Neuroscience, 2025, 2, 128
DOI: 10.4103/ATN.ATN-D-25-00001

Current Update on Transcellular Brain Drug Delivery

Bhakti Pawar, Nupur Vasdev, Tanisha Gupta, Mahi Mhatre, Anand More, Neelima Anup and Rakesh Kumar Tekade

Pharmaceutics, 2022, 14, 2719
DOI: 10.3390/pharmaceutics14122719

Emerging functions and applications of exosomes in oral squamous cell carcinoma

Yingchun Qie, Xia Sun, Yongqiang Yang and Tao Yan

J Oral Pathology Medicine, 2023, 52, 886
DOI: 10.1111/jop.13479

Polyphenol functional self-assembled drug delivery systems: Mechanism, application, and future intelligent precision assembly mode

Jiamin Feng, Xiaorong Wei, Qi Huang, Mengqi Li, Haiyan He, Li Han, Sanhu Fan, Taigang Mo, Junzhi Lin, Haozhou Huang and Dingkun Zhang

Nano Research, 2024, 18, 94907608
DOI: 10.26599/NR.2025.94907608

Advanced micro-/nanotechnologies for exosome encapsulation and targeting in regenerative medicine

Hasti Tashak Golroudbari, Seyedeh Parnian Banikarimi, Aryan Ayati, Alireza Hadizadeh, Zahra Khorasani Zavareh, Kiana Hajikhani, Asieh Heirani-Tabasi, Mohsen Ahmadi Tafti, Saeed Davoodi and Hossein Ahmadi Tafti

Clin Exp Med, 2023, 23, 1845
DOI: 10.1007/s10238-023-00993-7

Obeticholic acid-loaded exosomes attenuate liver fibrosis through dual targeting of the FXR signaling pathway and ECM remodeling

Arezou Azizsoltani, Behzad Hatami, Mohammad Reza Zali, Vahideh Mahdavi, Kaveh Baghaei and Effat Alizadeh

Biomedicine & Pharmacotherapy, 2023, 168, 115777
DOI: 10.1016/j.biopha.2023.115777

Emerging delivery systems based on aqueous two-phase systems: A review

Yaowen Zhang, Yankun Luo, Jingqi Zhao, Wenzhuo Zheng, Jun Zhan, Huaping Zheng and Feng Luo

Acta Pharmaceutica Sinica B, 2024, 14, 110
DOI: 10.1016/j.apsb.2023.08.024

Recent progresses in exosome-based systems for targeted drug delivery to the brain

Santosh Bashyal, Chhitij Thapa and Sangkil Lee

Journal of Controlled Release, 2022, 348, 723
DOI: 10.1016/j.jconrel.2022.06.011

Exosomes as Nanocarriers for Theragnostic miRNA Markers in Nonsmall Cell Lung Cancer Therapy

Ziyu Jiang, Yun He, Wenlong Ding, Siyao Zhu, Qinyuan Li, Xiuchun Sun, Meiguang Bian, Jiege Huo and Haisheng Qian

Journal of Nanomaterials, 2022, 2022
DOI: 10.1155/2022/8402500

The Promising Role of Natural Exosomal Nanoparticles in Cancer Chemoimmunotherapy

Archana Premnath, Sonu Benny, Aneesh Thankappan Presanna and Sabitha Mangalathillam

CDM, 2022, 23, 723
DOI: 10.2174/1389200223666220627103213

Concept of theranostic Exosomes: Potential diagnostic and therapeutic approaches for brain cancer therapy

Bhima Wagh, Nidhi Verma, Aseem Setia, Komal Rani, Nandini Vinodrao Randhave, Vikas Kumar, Vaishali, Ankit Kumar Malik and Madaswamy S. Muthu

Journal of Drug Delivery Science and Technology, 2025, 113, 107340
DOI: 10.1016/j.jddst.2025.107340

Targeted Delivery of Exosomes Armed with Anti-Cancer Therapeutics

Hojun Choi, Hwayoung Yim, Cheolhyoung Park, So-Hee Ahn, Yura Ahn, Areum Lee, Heekyoung Yang and Chulhee Choi

Membranes, 2022, 12, 85
DOI: 10.3390/membranes12010085

Breast Cancer Therapy: The Potential Role of Mesenchymal Stem Cells in Translational Biomedical Research

Pietro Gentile

Biomedicines, 2022, 10, 1179
DOI: 10.3390/biomedicines10051179

Milk-derived exosomes as a promising vehicle for oral delivery of hydrophilic biomacromolecule drugs

Yuting Li, Liyun Xing, Lingling Wang, Xi Liu, Licheng Wu, Mingjie Ni, Zhou Zhou, Lian Li, Xiuxiu Liu and Yuan Huang

Asian Journal of Pharmaceutical Sciences, 2023, 18, 100797
DOI: 10.1016/j.ajps.2023.100797

CircBTBD7-420aa Regulates the Progression of Atherosclerosis

Xiongkang Gan, Boyu Chi, Xin Zhang, Mengmeng Ren, Hengjie Bie, Qiaowei Jia, Yahong Fu, Chengcheng Li, Hanxiao Zhou, Shu He, Yanjun Wang, Yuli Chen, Sheng Zhang, Qian Zhang, Zhenyu Zhao, Weixin Sun, Qiangba Yangzong, Ciren Zhongga, Renyou Pan, Xiumei Chen and Enzhi Jia

JACC: Basic to Translational Science, 2025, 10, 131
DOI: 10.1016/j.jacbts.2024.09.003

Stem Cell Mimicking Nanoencapsulation for Targeting Arthritis

Min Jun Shin, Jun Young Park, Dae Ho Lee and Dongwoo Khang

IJN, 2021, Volume 16, 8485
DOI: 10.2147/IJN.S334298

High‐Sensitivity SPR Biosensor for Tumor Cell Exosome Detection Based on Ge‐Doped Fiber Core PCF

Licui Ji, Honggang Pan, Hongli Dai, Qingcheng You, Yukun Zhu, Xing Wang and Xu Gao

Journal of Biophotonics, 2026, 19
DOI: 10.1002/jbio.70222

MSC-Exos: Important active factor of bone regeneration

Sihang Ren, Yuyang Lin, Wenyue Liu, Liqun Yang and Muxin Zhao

Front. Bioeng. Biotechnol., 2023, 11
DOI: 10.3389/fbioe.2023.1136453

Injectable decellularized extracellular matrix hydrogel loaded with exosomes encapsulating curcumin for prevention of cardiac fibrosis after myocardial infarction

Yuanyuan Wang, Jingjing Wang, Chunxia Liu, Jingjing Li, Kunyan Lu, Qian Yu, Yanxia Zhang and Zhenya Shen

Journal of Materials Science & Technology, 2023, 167, 50
DOI: 10.1016/j.jmst.2023.06.005

Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy

Mohsen Karami Fath, Seyed Sajjad Zadian, Samaneh Mohammad Bagherzadeh Torbati, Vahid Saqagandomabadi, Omid Yousefi Afshar, Mohammad Khalilzad, Sara Abedi, Afshin Moliani and Ghasem Barati

CMM, 2025, 25, 431
DOI: 10.2174/0115665240274818231207054037

Therapeutic potential of exosomes derived from mesenchymal stem cells for treatment of systemic lupus erythematosus

Shima Famil Samavati, Reza Yarani, Sara Kiani, Zohreh HoseinKhani, Masomeh Mehrabi, Steven Levitte, Rosita Primavera, Shashank Chetty, Avnesh S. Thakor and Kamran Mansouri

J Inflamm, 2024, 21
DOI: 10.1186/s12950-024-00381-2

Advanced Therapeutic Approaches Based on Small Extracellular Vehicles (sEVs) For the Regeneration of Spinal Cord Injuries

Anam Anjum, Alvin Chan, Hafiz Bilawal Hussain and Yogeswaran Lokanathan

IJN, 2025, Volume 20, 7415
DOI: 10.2147/IJN.S522028

Exosomes enriched with miR-124-3p show therapeutic potential in a new microfluidic triculture model that recapitulates neuron–glia crosstalk in Alzheimer’s disease

Artemizia Évora, Gonçalo Garcia, Ana Rubi, Eleonora De Vitis, Ana Teresa Matos, Ana Rita Vaz, Francesca Gervaso, Giuseppe Gigli, Alessandro Polini and Dora Brites

Front. Pharmacol., 2025, 16
DOI: 10.3389/fphar.2025.1474012

Basic Guide for Approaching Drug Delivery with Extracellular Vesicles

Sergey Brezgin, Oleg Danilik, Alexandra Yudaeva, Artyom Kachanov, Anastasiya Kostyusheva, Ivan Karandashov, Natalia Ponomareva, Andrey A. Zamyatnin, Alessandro Parodi, Vladimir Chulanov and Dmitry Kostyushev

IJMS, 2024, 25, 10401
DOI: 10.3390/ijms251910401

Harnessing stem cell-derived exosomes: a promising cell-free approach for spinal cord injury

Miaoman Lin, Farzaneh Alimerzaloo, Xingjin Wang, Obada Alhalabi, Sandro M. Krieg, Thomas Skutella and Alexander Younsi

Stem Cell Res Ther, 2025, 16
DOI: 10.1186/s13287-025-04296-4

Mesenchymal Stem Cell-Derived Extracellular Vesicles: Pleiotropic Impacts on Breast Cancer Occurrence, Development, and Therapy

Yiling Guo, Yujia Zhai, Longyuan Wu, Yazhuo Wang, Puzhen Wu and Lixia Xiong

IJMS, 2022, 23, 2927
DOI: 10.3390/ijms23062927

Immune cells-derived exosomes function as a double-edged sword: role in disease progression and their therapeutic applications

Ali Hazrati, Sara Soudi, Kosar Malekpour, Mohammad Mahmoudi, Arezou Rahimi, Seyed Mahmoud Hashemi and Rajender S. Varma

Biomark Res, 2022, 10
DOI: 10.1186/s40364-022-00374-4

Stem Cells and Their Derivatives in Cardiac Fibrosis Therapy: Challenges and Perspectives

Adrian Piwowar, Zuzanna Zolbach, Julia Rydzek, Natalia Skonieczna, Katarzyna Rojek, Mateusz Żołyniak, Julia Soczyńska and Sławomir Woźniak

Cells, 2026, 15, 656
DOI: 10.3390/cells15080656

Boron Agent Delivery Platforms Based on Natural Products for Boron Neutron Capture Therapy

Riku Kawasaki, Yamato Miura, Nanami Kono, Seiya Fujita, Keita Yamana and Atsushi Ikeda

ChemMedChem, 2024, 19
DOI: 10.1002/cmdc.202400323

Preparing the Bone Tissue Regeneration Ground by Exosomes: From Diagnosis to Therapy

Batla Al-Sowayan, Farah Alammari and Alaa Alshareeda

Molecules, 2020, 25, 4205
DOI: 10.3390/molecules25184205

Bioengineering of Extracellular Vesicles: Exosome-Based Next-Generation Therapeutic Strategy in Cancer

Priyanka Saha, Suchisnigdha Datta, Sukanya Ghosh, Anurima Samanta, Paramita Ghosh and Dona Sinha

Bioengineering, 2021, 8, 139
DOI: 10.3390/bioengineering8100139

SALL4 and microRNA: The Role of Let-7

Jun Liu, Madeline A. Sauer, Shaza G. Hussein, Junyu Yang, Daniel G. Tenen and Li Chai

Genes, 2021, 12, 1301
DOI: 10.3390/genes12091301

Inhibition of MiR-155 Using Exosomal Delivery of Antagomir Can Up-Regulate PTEN in Triple Negative Breast Cancer

Javad Razaviyan, Majid Sirati-Sabet, Ali Tafti, Razie Hadavi, Saeed Karima, Masoumeh Rajabibazl and Samira Mohammadi-Yeganeh

EMIDDT, 2024, 24, 1664
DOI: 10.2174/0118715303289859240214103350

Exosome-mediated repair of spinal cord injury: a promising therapeutic strategy

Tong Yu, Li-Li Yang, Ying Zhou, Min-Fei Wu and Jian-Hang Jiao

Stem Cell Res Ther, 2024, 15
DOI: 10.1186/s13287-023-03614-y

M1 macrophage-derived exosomal miR-126-5p promotes endothelial cell senescence and deep vein thrombosis by targeting splicing factor SRSF11

Peiyu Guo, Kaili Du, Yu Xiao, Ziran Zhou, Bing Wang and Zhen kai Lou

International Immunopharmacology, 2026, 169, 115891
DOI: 10.1016/j.intimp.2025.115891

The Evolving Role of Mesenchymal Stem Cells and Their Exosomes in Epilepsy Management: From Bench to Bedside

An Li, Zhuohui Zhao, Rulin Mi, Guofang Xue and Zhaoji Pan

Stem Cells International, 2026, 2026
DOI: 10.1155/sci/4989846

Therapeutic Potential of Exosomes in Pulmonary Fibrosis

Linshen Xie and Ye Zeng

Front. Pharmacol., 2020, 11
DOI: 10.3389/fphar.2020.590972

Drug Delivery to the Bone Microenvironment Mediated by Exosomes: An Axiom or Enigma

Sasmita Samal, Pratigyan Dash and Mamoni Dash

IJN, 2021, Volume 16, 3509
DOI: 10.2147/IJN.S307843

Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review)

Xinchi Luan, Xuezhe Wang, Gang Bian, Xiaoxuan Li, Ziru Gao, Zijiao Liu, Zhishang Zhang, Tianyue Han, Jinpeng Zhao, Hongjiao Zhao, Xinyue Luan, Wuhui Zhu, Lili Dong and Feifei Guo

Oncol Rep, 2024, 53
DOI: 10.3892/or.2024.8846

Exosomes: Insights and therapeutic applications in cancer

Anita Raj Panigrahi, Lankalapalli Srinivas and Jagadeesh Panda

Translational Oncology, 2022, 21, 101439
DOI: 10.1016/j.tranon.2022.101439

Individualized bio-scaffold encapsulating siPTEN-loaded exosomes for promoting neuronal regeneration in spinal cord injury

Zehan Shang, Zihao Liu, Min Han, Hao Fan, Dongxiao Lu, Zijian Zhou, Zhihai Wang, Yuming Li, Xiaofeng Wang, Bingcheng Wang, Baogeng Huai, Youqiang Cui, Huitang Xia, Shan Wang and Tao Xin

Composites Part B: Engineering, 2024, 270, 111146
DOI: 10.1016/j.compositesb.2023.111146

Zwitterionic polymers: Addressing the barriers for drug delivery

Muzi Li, Wen Zhang, Jiaxin Li, Yinghe Qi, Chen Peng, Nan Wang, Huili Fan and Yan Li

Chinese Chemical Letters, 2023, 34, 108177
DOI: 10.1016/j.cclet.2023.108177

Mesenchymal stem cell derived exosomes as Nanodrug carrier of doxorubicin combined with PVT1 siRNA inhibits the progression of gastric cancer

Deliang Ouyang, Haibin Li, Kang Luo, Mingming Huang, Song Yan and Li Zhou

Arab Journal of Gastroenterology, 2025, 26, 149
DOI: 10.1016/j.ajg.2025.01.012

A Comprehensive Review on Exosome: Recent Progress and Outlook

Paras Agarwal, Adiba Anees, Raval Kavit Harsiddharay, Pranesh Kumar and Pushpendra Kumar Tripathi

PNT, 2024, 12, 2
DOI: 10.2174/2211738511666230523114311

Green Onion-Derived Exosome-like Nanoparticles Prevent Ferroptotic Cell Death Triggered by Glutamate: Implication for GPX4 Expression

Han Jun Yoon, Jun Pil Won, Hyuk Gyoon Lee and Han Geuk Seo

Nutrients, 2024, 16, 3257
DOI: 10.3390/nu16193257

Emerging Potential of Exosomal Non-coding RNA in Parkinson’s Disease: A Review

Peng Zhang, Madiha Rasheed, Junhan Liang, Chaolei Wang, Lin Feng and Zixuan Chen

Front. Aging Neurosci., 2022, 14
DOI: 10.3389/fnagi.2022.819836

Ionizing radiation leads to exosome secretion in macrophages through MYC-mediated pathways

Hanui Lee, Gyeong Han Jeong, Geun-Joong Kim, Seung Sik Lee, Byung Yeoup Chung, Hyoung-Woo Bai and Mohammad H. Ghazimoradi

PLoS One, 2025, 20, e0336322
DOI: 10.1371/journal.pone.0336322

Engineered stem cell exosomes for oral and maxillofacial wound healing

Ming Hao, MengNa Duan, Zhijing Yang, Hengzong Zhou, Shuangji Li, Jingcheng Xiang, Han Wu, Huimin Liu, Lu Chang, Dongxu Wang and Weiwei Liu

Front. Bioeng. Biotechnol., 2022, 10
DOI: 10.3389/fbioe.2022.1038261

Extracellular vesicle hybrid engineering for DDS and medical application

Ryosuke Mizuta and Kazunari Akiyoshi

DDS, 2021, 36, 90
DOI: 10.2745/dds.36.90