Preparation and assessment of agar/TEMPO-oxidized bacterial cellulose cryogels for hemostatic applications

Kaushal R. Shakya, Kuldeep Nigam, Arpit Sharma, Kousar Jahan, Amit Kumar Tyagi and Vivek Verma

J. Mater. Chem. B, 2024, 12, 3453
DOI: 10.1039/D4TB00047A

Photodynamic hemostatic silk fibroin film with photo-controllable modulation of macrophages for bacteria-infected wound healing

Xiaoxuan Tang, Wenpin Wu, Shuxuan Zhang, Chang He, Kewei Fan, Yulan Fan, Xuewa Yang, Jiaying Li, Yumin Yang and Jue Ling

Biomater. Sci., 2025, 13, 606
DOI: 10.1039/D4BM01038H

Rational design and latest advances of polysaccharide-based hydrogels for wound healing

Hao Hu and Fu-Jian Xu

Biomater. Sci., 2020, 8, 2084
DOI: 10.1039/D0BM00055H

Emerging chitin nanogels/rectorite nanocomposites for safe and effective hemorrhage control

Jianwei Zhang, Shuai Xue, Xinyi Zhu, Yanan Zhao, Yun Chen, Jun Tong, Xiaowen Shi, Yumin Du, Zibiao Zhong and Qifa Ye

J. Mater. Chem. B, 2019, 7, 5096
DOI: 10.1039/C9TB01019J

Tannic acid-loaded mesoporous silica for rapid hemostasis and antibacterial activity

Chengwei Wang, Huayi Zhou, Haoyi Niu, Xiaoyu Ma, Yuan Yuan, Hua Hong and Changsheng Liu

Biomater. Sci., 2018, 6, 3318
DOI: 10.1039/C8BM00837J

Topical hemostatic materials for coagulopathy

Bingjie Hu, Guochen Bao, Xiaoxue Xu and Kai Yang

J. Mater. Chem. B, 2022, 10, 1946
DOI: 10.1039/D1TB02523F

A thermosensitive poloxamer hydrogel with ofloxacin and cationic microparticles for antibacterial and hemostatic applications

Kan Ji, Hanlu Chen, Yang Su, Bing Yuan, Zhenfei Song, Kai Zhang, Guochao Zhang, Yang Hu, Feng Duan and Fu-Jian Xu

Biomater. Sci., 2025, 13, 3048
DOI: 10.1039/D5BM00375J

Urushiol-functionalized mesoporous silica nanoparticles and their self-assembly into a Janus membrane as a highly efficient hemostatic material

Jiawen Chen, Wei Cheng, Shuning Chen, Wenqin Xu, Jinhuo Lin, Haiqing Liu and Qinhui Chen

Nanoscale, 2018, 10, 22818
DOI: 10.1039/C8NR05882B

Fabricating poly(vinyl alcohol)/gelatin composite sponges with high absorbency and water-triggered expansion for noncompressible hemorrhage and wound healing

Xiao Yang, Miao Chen, PengPeng Li, Zhixiao Ji, Mingshan Wang, Yakai Feng and Changcan Shi

J. Mater. Chem. B, 2021, 9, 1568
DOI: 10.1039/D0TB02480E

A self-gelling starch-based sponge for hemostasis

Wenjie Huang, Juan Wu, Zhenhua Huang, Dong Zhang, Fangping Chen and Changsheng Liu

J. Mater. Chem. B, 2023, 11, 1331
DOI: 10.1039/D2TB02224A

Thermally adaptive iohexol-loaded microcages for local computerized tomography

Jie Qiao, Jiao Dong, Jianhao Wang, Shuxuan Liu, Yao Wang, Xian Li, Hao Li and Guofu Zhou

J. Mater. Chem. B, 2025, 13, 3669
DOI: 10.1039/D4TB02531H

Controlled release of KGF-2 for regulation of wound healing by KGF-2 complexed with “lotus seedpod surface-like” porous microspheres

Hao Pan, Changcan Shi, Rongshuai Yang, Guanghui Xi, Chao Lu, Xuanxin Yang, Jie Chen, Xiaojie Wang, Lei Chen and Jingye Pan

J. Mater. Chem. B, 2021, 9, 4039
DOI: 10.1039/D1TB00148E

Armoring a liposome-integrated tissue factor with sacrificial CaCO3 to form potent self-propelled hemostats

Chengkun Liu, Zhuang Shi, Jingyan Zhu, Chang Liu, Xiaodan Liu, Naseer Ullah Khan, Shihai Liu, Xiaojuan Wang, Xiaoqiang Wang and Fang Huang

J. Mater. Chem. B, 2023, 11, 2778
DOI: 10.1039/D2TB02140D

Evaluation of absorbable hemostatic agents of polyelectrolyte complexes using carboxymethyl starch and chitosan oligosaccharide both in vitro and in vivo

Xingtao Chen, Yonggang Yan, Hong Li, Xuehong Wang, Songchao Tang, Quan Li, Jie Wei and Jiacan Su

Biomater. Sci., 2018, 6, 3332
DOI: 10.1039/C8BM00628H

A natural polyphenol-functionalized chitosan/gelatin sponge for accelerating hemostasis and infected wound healing

Yujie Sun, Tengfei Miao, Yu Wang, Xiaochen Wang, Jie Lin, Nana Zhao, Yang Hu and Fu-Jian Xu

Biomater. Sci., 2023, 11, 2405
DOI: 10.1039/D2BM02049A

Highly resilient, biocompatible, and antibacterial carbon nanotube/hydroxybutyl chitosan sponge dressing for rapid and effective hemostasis

Wei Zhang, Liming Zhao, Chen Gao, Jie Huang, Qingwen Li and Zhijun Zhang

J. Mater. Chem. B, 2021, 9, 9754
DOI: 10.1039/D1TB01911B

Hemostatic nanotechnologies for external and internal hemorrhage management

Liying Wang, Xinru You, Chunlei Dai, Tong Tong and Jun Wu

Biomater. Sci., 2020, 8, 4396
DOI: 10.1039/D0BM00781A

Preparation and hemostatic performance of composites using tourmaline and shells as main raw materials

Junping Meng, Zhiling Yang, Chandrasekar Srinivasakannan, Xinhui Duan, Tao Guo and Jinsheng Liang

New J. Chem., 2024, 48, 11338
DOI: 10.1039/D4NJ01640H

Well-ordered mesoporous silica and bioactive glasses: promise for improved hemostasis

Sara Pourshahrestani, Nahrizul Adib Kadri, Ehsan Zeimaran and Mark R. Towler

Biomater. Sci., 2019, 7, 31
DOI: 10.1039/C8BM01041B

Metal-coordination synthesis of a natural injectable photoactive hydrogel with antibacterial and blood-aggregating functions for cancer thermotherapy and mild-heating wound repair

Kiyan Musaie, Samin Abbaszadeh, Vahideh Nosrati-Siahmazgi, Mostafa Qahremani, Shige Wang, Mohammad Reza Eskandari, Seyyed Vahid Niknezhad, Fakhri Haghi, Yulin Li, Bo Xiao and Mohammad-Ali Shahbazi

Biomater. Sci., 2023, 11, 2486
DOI: 10.1039/D2BM01965E

Polyphosphate as an antithrombotic target and hemostatic agent

Ruoyu Chen, Mingdong Huang and Peng Xu

J. Mater. Chem. B, 2023, 11, 7855
DOI: 10.1039/D3TB01152F

Sheet-like Janus hemostatic dressings with synergistic effects of cardanol hemostasis and quaternary ammonium salt antibacterial action

Yuxia Zhang, Xiaoyu Lu, Chongyi Chi, Yanyan Zheng and Qinhui Chen

J. Mater. Chem. B, 2022, 10, 9413
DOI: 10.1039/D2TB02082C

Development of an efficient hemostatic material based on cuttlefish ink nanoparticles loaded in cuttlebone biocomposite

Zeinab Janahmadi, Safieh Momeni, Hamed Manoochehri and Shadi Talebi

J. Mater. Chem. B, 2024, 12, 4172
DOI: 10.1039/D3TB01966G

Rational design of porous starch/hyaluronic acid composites for hemostasis

Yanling Wang, Guangwan Liu, Lijuan Wu, Hongyuan Qu, Deli Song, Hailong Huang, Changlin Wu and Min Xu

International Journal of Biological Macromolecules, 2020, 158, 1319
DOI: 10.1016/j.ijbiomac.2020.05.018

Thrombin-Loaded TA-CaCO3 Microspheres as a Budget, Adaptable, and Highly Efficient Hemostatic

Pengzhong Shi, Daozhen Zhou, Yaxin Zhu, Bo Peng, Nannan Shao and Xingjie Zan

ACS Appl. Bio Mater., 2021, 4, 1030
DOI: 10.1021/acsabm.0c01475

Design of modified chitosan/oxidized dextran based enhanced dual network adhesive hydrogels; An effective approach promoting wound healing

Hina Khadim, Anila Asif, Rabia Zeeshan, Tayyaba Ilyas, Arsalan Ahmed Ansari, Zulfiqar Ali and Mustansara Yaqub

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2025, 727, 138230
DOI: 10.1016/j.colsurfa.2025.138230

Polyamino acid antibacterial hydrogel with photothermal effect for wound healing

Nian Liu, Sen Liang, Jingtao Li, Qi Li, Shuo Bai and Jing Hu

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 693, 133940
DOI: 10.1016/j.colsurfa.2024.133940

Tannic Acid Cross‐linked Polysaccharide‐Based Multifunctional Hemostatic Microparticles for the Regulation of Rapid Wound Healing

Na Li, Xiao Yang, Wen Liu, Guanghui Xi, Mingshan Wang, Bin Liang, Zhaipu Ma, Yakai Feng, Hao Chen and Changcan Shi

Macromolecular Bioscience, 2018, 18
DOI: 10.1002/mabi.201800209

Polymer Applied in Hydrogel Wound Dressing for Wound Healing: Modification/Functionalization Method and Design Strategies

Yongping Liang, Jiahui He, Meng Li, Zhenlong Li, Jiaxin Wang, Juntang Li and Baolin Guo

ACS Biomater. Sci. Eng., 2025, 11, 1921
DOI: 10.1021/acsbiomaterials.4c02054

Utilizing epoxy Bletilla striata polysaccharide collagen sponge for hemostatic care and wound healing

Zhongyu Tang, Nianhua Dan and Yining Chen

International Journal of Biological Macromolecules, 2024, 259, 128389
DOI: 10.1016/j.ijbiomac.2023.128389

Construction of porous structure-based carboxymethyl chitosan/ sodium alginate/ tea polyphenols for wound dressing

Huimin Li, Shen Shen, Kejing Yu, Hongbo Wang and Jiajia Fu

International Journal of Biological Macromolecules, 2023, 233, 123404
DOI: 10.1016/j.ijbiomac.2023.123404

Water-Swellable Cellulose Nanofiber Aerogel for Control of Hemorrhage from Penetrating Wounds

Li Wang, Chenglin Zhang, Wei Zhao, Wei Li, Guodong Wang, Xuhui Zhou and Qiang Zhang

ACS Appl. Bio Mater., 2022, 5, 4886
DOI: 10.1021/acsabm.2c00609

Novel Flowable Hemostatic Agent ActiClot: Efficacy and Safety Assessment in Rat and Porcine Models

Hee-Jung Kim, Su-Kyoung Lee, Yun-Jeh Ko, Soo-Hyeon Jeon, Eun-Jin Kim, Oh-Hyeong Kwon and Yang-Hyun Cho

JCM, 2024, 13, 4770
DOI: 10.3390/jcm13164770

A hierarchical bilayer sponge dressing based on QCMCS@GO/PLA for synergistic wound healing via hemostasis and anti-adhesion

Haishui Jiang, Huiting Fu, Qin Wei and Yingbo Wang

International Journal of Biological Macromolecules, 2026, 344, 150565
DOI: 10.1016/j.ijbiomac.2026.150565

Engineered Hemostatic Biomaterials for Sealing Wounds

Hossein Montazerian, Elham Davoodi, Avijit Baidya, Sevana Baghdasarian, Einollah Sarikhani, Claire Elsa Meyer, Reihaneh Haghniaz, Maryam Badv, Nasim Annabi, Ali Khademhosseini and Paul S. Weiss

Chem. Rev., 2022, 122, 12864
DOI: 10.1021/acs.chemrev.1c01015

Advances in haemostatic sponges: Characteristics and the underlying mechanisms for rapid haemostasis

Akriti Nepal, Huong D.N. Tran, Nam-Trung Nguyen and Hang Thu Ta

Bioactive Materials, 2023, 27, 231
DOI: 10.1016/j.bioactmat.2023.04.008

Preparation and Application of Hemostatic Hydrogels

Minyu Zhou, Xiang Lin, Li Wang, Chaoyu Yang, Yunru Yu and Qingfei Zhang

Small, 2024, 20
DOI: 10.1002/smll.202309485

A bioactive nanocomposite sponge for simultaneous hemostasis and antimicrobial therapy

Jiani Lei, Shanshan Li, Shuang Liu, Qingyuan Wu, Bolong Xu, Zhijun Huang, Nier Wu, Xiaolu Xiong, Huiyu Liu and Dongsheng Zhou

Nano Res., 2023, 16, 4004
DOI: 10.1007/s12274-022-5226-1

Recent Advances in Injectable Dual Crosslinking Hydrogels for Biomedical Applications

Wenlin Chu, Mingxi Nie, Xiang Ke, Jun Luo and Jianshu Li

Macromolecular Bioscience, 2021, 21
DOI: 10.1002/mabi.202100109

Degradable Gelatin-Based IPN Cryogel Hemostat for Rapidly Stopping Deep Noncompressible Hemorrhage and Simultaneously Improving Wound Healing

Ying Huang, Xin Zhao, Zhiyi Zhang, Yongping Liang, Zhanhai Yin, Baojun Chen, Lang Bai, Yong Han and Baolin Guo

Chem. Mater., 2020, 32, 6595
DOI: 10.1021/acs.chemmater.0c02030

Multifunctional injectable oxidized sodium alginate/carboxymethyl chitosan hydrogel for rapid hemostasis

Xuanyu Liu, Junjie Hu, Yinchun Hu, Yeying Liu, Yan Wei and Di Huang

Colloids and Surfaces B: Biointerfaces, 2025, 245, 114346
DOI: 10.1016/j.colsurfb.2024.114346

Reuterin integrated as dynamic imine crosslinks strengthens creatine modified chitosan hydrogel and boosts antibacterial efficacy

Yongsheng Zheng, Kai You, Cuiping Guo, Zhijie Geng, Yuwei Gao, Zhaoming Liu, Dong Yang, Huilong Guo and Jun Huang

Carbohydrate Research, 2025, 558, 109716
DOI: 10.1016/j.carres.2025.109716

Ultrafast Self‐Gelling, Adhesive, Anti‐Bacterial Coacervate‐Based Powders for Enhanced Hemostasis and Wound Healing

Hui Zhou, Bin Kong, Yi Cheng, Si Meng, Haifeng Dong, Cheng Qi, Tiantian Kong, Yuanjin Zhao and Zhou Liu

Small, 2025, 21
DOI: 10.1002/smll.202409164

N-halamine modified multiporous bacterial cellulose with enhanced antibacterial and hemostatic properties

Shumin Zhang, Lin Li, Xuehong Ren and Tung-Shi Huang

International Journal of Biological Macromolecules, 2020, 161, 1070
DOI: 10.1016/j.ijbiomac.2020.06.053

Pomegranate-peel-chitosan-gelatin composite: A hemostatic dental sponge with antibacterial enhancement

Lale Rozykulyyeva, Prihartini Widiyanti and Suryani Dyah Astuti

Dent. J., 2025, 58, 171
DOI: 10.20473/j.djmkg.v58.i2.p171-179

Bactericidal Hemostatic Sponge: A Point of Care Solution to Combat Traumatic Injury

Rajib Dey, Riya Mukherjee, Sudip Mukherjee and Jayanta Haldar

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202404176

Physical Double‐Network Hydrogel Adhesives with Rapid Shape Adaptability, Fast Self‐Healing, Antioxidant and NIR/pH Stimulus‐Responsiveness for Multidrug‐Resistant Bacterial Infection and Removable Wound Dressing

Xin Zhao, Yongping Liang, Ying Huang, Jiahui He, Yong Han and Baolin Guo

Adv Funct Materials, 2020, 30
DOI: 10.1002/adfm.201910748

Anisotropic cardanol hemostasis and silver antibacterial Janus nanosheet and its blood coagulation promotion

Zhe Chen, Yuxia Zhang, Yanyan Zheng, Xueqing Xiao and Qinhui Chen

Materials Today Communications, 2024, 39, 108870
DOI: 10.1016/j.mtcomm.2024.108870

A hydrophobic cationic polyphenol coating for versatile antibacterial and hemostatic devices

Li Long, Yaqian Fan, Xue Yang, Xiaokang Ding, Yang Hu, Guochao Zhang and Fu-Jian Xu

Chemical Engineering Journal, 2022, 444, 135426
DOI: 10.1016/j.cej.2022.135426

Benzeneboronic−alginate/quaternized chitosan−catechol powder with rapid self-gelation, wet adhesion, biodegradation and antibacterial activity for non-compressible hemorrhage control

Yan Du, Xingtao Chen, Lin Li, Heng Zheng, Aiping Yang, Hong Li and Guoyu Lv

Carbohydrate Polymers, 2023, 318, 121049
DOI: 10.1016/j.carbpol.2023.121049

Calcium oxide/silica nanocomposite and L. coromandelica bark incorporated κ-carrageenan/sodium alginate hydrogel for rapid hemostasis

H. Mohamed Amsath Haseef, S. Dinesh, J. Prakash, M.S. Marvaan, Sundar Madasamy, Balashanmugan Pannerselvam and G. Devanand Venkatasubbu

International Journal of Biological Macromolecules, 2024, 254, 127951
DOI: 10.1016/j.ijbiomac.2023.127951

Comprehensive Review of Mesoporous Silica Nanoparticles: Drug Loading, Release, and Applications as Hemostatic Agents

Talib M. Albayati, Saja M. Alardhi, Ali H. Khalbas, Zainab J. Humdi, Nisreen S. Ali, Issam K. Salih, Noori M. Cata Saady, Sohrab Zendehboudi and Mahir A. Abdulrahman

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202400450

In situ gels for postoperative cancer treatment: Current status and challenges

Zixuan Ye, Li Zhou, Xia Luo, Kaifei Xue, Lizhen Liang, Zihui Meng, Pengrong Zhu, Yanan Li and He Huang

Chemical Engineering Journal, 2025, 505, 159621
DOI: 10.1016/j.cej.2025.159621

In Vivo and In Vitro Investigation of a Novel Gelatin/Sodium Polyacrylate Composite Hemostatic Sponge for Topical Bleeding

Nusrat Jahan, Md Sowaib Ibne Mahbub, Byong-Taek Lee and Sang Ho Bae

JFB, 2023, 14, 265
DOI: 10.3390/jfb14050265

Multifunctional Nanozyme Hydrogel with Procoagulant/Peroxidase/Photothermal Tri‐Activity for Emergency Hemostasis and Bacterial Eradication

Ye Zhang, Yilin Li, Weijia Zhang, Meng Zhang, Zhen Wang, Qiaoyu Li, Bing Fan, Qiongyi Wang, Caixiu Yang and Ying Li

Adv Healthcare Materials, 2026, 15
DOI: 10.1002/adhm.202503797

Polysaccharide-Based Lotus Seedpod Surface-Like Porous Microsphere with Precise and Controllable Micromorphology for Ultrarapid Hemostasis

Guanghui Xi, Wen Liu, Miao Chen, Qian Li, Xiao Hao, Mingshan Wang, Xiao Yang, Yakai Feng, Hongchao He, Changcan Shi and Wenzhong Li

ACS Appl. Mater. Interfaces, 2019, 11, 46558
DOI: 10.1021/acsami.9b17543

Systematic studies on blood coagulation mechanisms of halloysite nanotubes-coated PET dressing as superior topical hemostatic agent

Yue Feng, Xiang Luo, Fan Wu, Hongzhong Liu, Enyu Liang, Rong-Rong He and Mingxian Liu

Chemical Engineering Journal, 2022, 428, 132049
DOI: 10.1016/j.cej.2021.132049

Nanoengineered and highly porous 3D chitosan-graphene scaffold for enhanced antibacterial activity and rapid hemostasis

Priyadarshani Choudhary, Abhishek Shaw, Baskaran Ramalingam and Sujoy K. Das

International Journal of Biological Macromolecules, 2025, 306, 141521
DOI: 10.1016/j.ijbiomac.2025.141521

Natural polysaccharide-based hydrogels for hemostasis and wound healing: A review

Peng Wang, Yuji Pu and Bin He

Precision Medicine and Engineering, 2025, 2, 100016
DOI: 10.1016/j.preme.2025.100016

Efficacy and safety assessment of gelatin hemostatic matrix in a burr hole neurosurgical beagle model

Jun Ma, Shaolei Gan, Ruming Shu, Liangbin Zhou and Shangsi Chen

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-28075-6

Fabricating Oxidized Cellulose Sponge for Hemorrhage Control and Wound Healing

Shengyu Li, Xijin Wu, Ningning Bai, Jianyu Ni, Xianli Liu, Weiye Mao, Lu Jin, Hai Xiang, Huiying Fu and Qiyang Shou

ACS Biomater. Sci. Eng., 2023, 9, 6398
DOI: 10.1021/acsbiomaterials.3c00018

Preparation of self‐regulating/anti‐adhesive hydrogels and their ability to promote healing in burn wounds

Min Liang, Zhongmin Chen, Fuping Wang, Lan Liu, Runan Wei and Mei Zhang

J Biomed Mater Res, 2019, 107, 1471
DOI: 10.1002/jbm.b.34239

Super-expandable dual-crosslinking all-cellulose sponge: a physical and chemical solution for hemostasis in severe hemorrhage

Xinsen Lin, Siqi Zhang, Weijie Jiang, Wengang Dong, Xinli Wang, Kaili Hao, Wei Cao, Jing Wang, Jintao Dong, Xiaobo Lin, Wei Lei and Yafei Feng

International Journal of Biological Macromolecules, 2025, 311, 143837
DOI: 10.1016/j.ijbiomac.2025.143837

Thermoresponsive Gels with Embedded Starch Microspheres for Optimized Antibacterial and Hemostatic Properties

Yang Su, Hanlu Chen, Qian Liu, Xiaokang Ding, Rui Lian, Yang Hu and Fu-Jian Xu

ACS Appl. Mater. Interfaces, 2024, 16, 12321
DOI: 10.1021/acsami.3c19581

Preparation and application of hemostatic microspheres containing biological macromolecules and others

Zekai Ren, Yumei Wang, Han Wu, Hailin Cong, Bing Yu and Youqing Shen

International Journal of Biological Macromolecules, 2024, 257, 128299
DOI: 10.1016/j.ijbiomac.2023.128299

Bioadhesives: Current hotspots and emerging challenges

Haofang Zhu, Jiang Tian, Hongli Mao and Zhongwei Gu

Current Opinion in Biomedical Engineering, 2021, 18, 100271
DOI: 10.1016/j.cobme.2021.100271

Latest advance anti-inflammatory hydrogel wound dressings and traditional Lignosus rhinoceros used for wound healing agents

Safia Arbab, Hanif Ullah, Nehaz Muhammad, Weiwei Wang and Jiyu Zhang

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1488748

Hemostatic efficacy evaluation of radiation-crosslinked carboxymethyl cellulose granules and kappa-carrageenan/polyethylene oxide/polyethylene glycol dressing in rat bleeding models

Charito Tranquilan-Aranilla, Bin Jeremiah Barba, Lorna Relleve, Maria Amelita Estacio and Lucille Abad

J Biomater Appl, 2021, 35, 1143
DOI: 10.1177/0885328220968395

Layer-by-layer coating of carboxymethyl chitosan-gelatin-alginate on cotton gauze for hemostasis and wound healing

Weishi Zheng, Chuntao Chen, Xujun Zhang, Xiaodong Wen, Yuanxiang Xiao, Lin Li, Qingbo Xu, Feiya Fu, Hongyan Diao and Xiangdong Liu

Surface and Coatings Technology, 2021, 406, 126644
DOI: 10.1016/j.surfcoat.2020.126644

Surface-functionalized design of blood-contacting biomaterials for preventing coagulation and promoting hemostasis

Yi Wang, Weijie Zhai, Shujie Cheng, Jinghua Li and Hongyu Zhang

Friction, 2023, 11, 1371
DOI: 10.1007/s40544-022-0710-x

Engineered Molecular Therapeutics Targeting Fibrin and the Coagulation System: a Biophysical Perspective

Fanny Risser, Ivan Urosev, Joanan López-Morales, Yang Sun and Michael A. Nash

Biophys Rev, 2022, 14, 427
DOI: 10.1007/s12551-022-00950-w

Graphene-based hemostatic sponge

Bingxin Wu, Fanglin Du, Wenjing A, Guofeng Li and Xing Wang

Chinese Chemical Letters, 2022, 33, 703
DOI: 10.1016/j.cclet.2021.06.029

Assessment of a self-assembling peptide gel, SPG-178, in providing a clear operative field for trabeculectomy surgery for glaucoma in an animal model

Kenji Matsushita, Rumi Kawashima, Koji Uesugi, Haruka Okada, Hirokazu Sakaguchi, Andrew J. Quantock and Kohji Nishida

Sci Rep, 2020, 10
DOI: 10.1038/s41598-020-68171-3

Recent research advances in polysaccharide-based hemostatic materials: A review

Yan Fang, Wei Guo, Peng Ni and Haiqing Liu

International Journal of Biological Macromolecules, 2024, 271, 132559
DOI: 10.1016/j.ijbiomac.2024.132559

Preparation of green cellulose diacetate-based antibacterial wound dressings for wound healing

Chuang Xiao, Ge Zhang, Wencheng Liang, Zhaochuang Wang, Qiaohui Lu, Weibin Shi, Yan Zhou, Yong Guan and Meidong Lang

Front. Mater. Sci., 2022, 16
DOI: 10.1007/s11706-022-0599-3

The characterization and analysis of the compound hemostatic cotton based on Ca2+/poly (vinyl alcohol)/soluble starch-fish skin collagen

Chunchun Wang, Jiayi Guo, Qun Liu, Xu Zeng, Yue Liu, Yanping Deng, Yanli Lin, Xialing Wu, Hongju Deng, Linjing Chen, Wuyin Weng and Yucang Zhang

International Journal of Biological Macromolecules, 2024, 262, 130084
DOI: 10.1016/j.ijbiomac.2024.130084

Therapeutic sponge prevents postoperative breast cancer recurrence by sustainably dissociating into CD44-targeted nanoplatform

Junhui Sui, Mingda Zhao, Zhihao Guo, Jiafeng Li, Jie Chen, Hongli Chen, Jie Liang, Yong Sun, Xingdong Zhang and Yujiang Fan

Nano Res., 2024, 17, 1792
DOI: 10.1007/s12274-023-6017-z

Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b

Neha N. Parayath, Avani Parikh and Mansoor M. Amiji

Nano Lett., 2018, 18, 3571
DOI: 10.1021/acs.nanolett.8b00689

Comprehensive Assessment of Collagen/Sodium Alginate-Based Sponges as Hemostatic Dressings

Leilei Sun, Yanyan Shen, Mingbo Li, Qiuting Wang, Ruimin Li and Shunmin Gong

Molecules, 2024, 29, 2999
DOI: 10.3390/molecules29132999

Agarose Cryogels Loaded with Polydopamine Microspheres for Sustainable Wound Care with Enhanced Hemostatic and Antioxidant Properties

Kaushal R. Shakya, Nasim Mansoori, Anmol Anand, Vijay Sharma and Vivek Verma

ACS Appl. Bio Mater., 2024, 7, 6808
DOI: 10.1021/acsabm.4c00945

Bioactive Hydrogels with Pro‐coagulation Effect for Hemostasis†

Quanshi Guo, Yihang Ding, Lisha Yu, Zongrui Tong and Zhengwei Mao

Chin. J. Chem., 2024, 42, 87
DOI: 10.1002/cjoc.202300380

The impact of spatial structures of collagen on the hemostatic properties of collagen/calcium alginate composite membranes

Haofei Xu, Yang Liu, Yaozhi Huang, Juntao Zhang, Zhenhua Qin, Benmei Wei, Chengzhi Xu, Lian Zhu and Haibo Wang

International Journal of Biological Macromolecules, 2025, 288, 138753
DOI: 10.1016/j.ijbiomac.2024.138753

Polysaccharide-based hydrogels: New insights and futuristic prospects in wound healing

Neha Raina, Rakesh Pahwa, Vijay Kumar Thakur and Madhu Gupta

International Journal of Biological Macromolecules, 2022, 223, 1586
DOI: 10.1016/j.ijbiomac.2022.11.115

Bioabsorbable Fibrillar Gauze Dressing Based on N-Carboxyethyl Chitosan Gelling Fibers for Fatal Hemorrhage Control

Lili Deng, Liu Wang, Li Li, Zuguang Gong, Ruilan Wang, Wendi Fei, Yingshan Zhou and Fang Wang

ACS Appl. Bio Mater., 2023, 6, 899
DOI: 10.1021/acsabm.2c01089

Sponge‐like chitosan‐based nanostructured antibacterial material as a topical hemostat

Ayca Bal‐Ozturk, Oksan Karal‐Yilmaz, Zeynep Puren Akguner, Soner Aksu, Arzu Tas and Hulya Olmez

J of Applied Polymer Sci, 2019, 136
DOI: 10.1002/app.47522

Preparation and property of soluble hemostatic material with 3D knitted structure

Shiyao Zhang, Tingting Shi, Guangjun Wu, Qi Zhang and Pibo Ma

Journal of Industrial Textiles, 2022, 52
DOI: 10.1177/15280837221107399

Anti-swelling polysaccharide-based cryogel sponge with rich positive charge for non-compressive hemostasis and wound healing

Fangzheng Zhao, Qiqi Han, Tong Wu, Chunyue Zhao, Enchang Liu, Shuaibing Huang, Tingbin Zhang, Rijie Wang and Jinfeng Xing

International Journal of Biological Macromolecules, 2025, 318, 145239
DOI: 10.1016/j.ijbiomac.2025.145239

Hemostatic efficacy of composite polysaccharide powder (starch-chitosan) for emergency bleeding control: An animal model study

Mohsen Mardani, Hamid Reza Eftekharian, Mahmood Naseri, Seyed Mohammad Hashem Hosseini, Hamid Mohammadi, Hossein Danesteh, Niloofar Ghadimi and Saeed Fazel

Surgery, 2022, 172, 1007
DOI: 10.1016/j.surg.2022.04.054

Protein fibril-chitosan composite films incorporated with epigallocatechin gallate for emergency hemostasis

Ziyan Li, Fengguang Ma, Yang You, Mengjia Jin, Yunqi Li, Yuan Liu, Hui Zhao and Bing Hu

Colloids and Surfaces B: Biointerfaces, 2026, 259, 115362
DOI: 10.1016/j.colsurfb.2025.115362

Immobilized thrombin on X-ray radiopaque polyvinyl alcohol/chitosan embolic microspheres for precise localization and topical blood coagulation

Xiaohong Li, Xiongfa Ji, Kun Chen, Muhammad Wajid Ullah, Basen Li, Jiameng Cao, Lin Xiao, Jun Xiao and Guang Yang

Bioactive Materials, 2021, 6, 2105
DOI: 10.1016/j.bioactmat.2020.12.013

Cationic starch microparticles with integrated antibacterial and hemostatic performance

Yang Su, MengXin Niu, KaiDong Xu, Chen Xu, PeiLang Yang, Yang Hu and Fu-Jian Xu

Sci. China Technol. Sci., 2024, 67, 3235
DOI: 10.1007/s11431-023-2577-7

Multi-functional platelets: translating biological functions into therapeutic applications

Chen-Yu Zou, Yun-Tian Deng, Xin-Rui Lin and Hui-Qi Xie

Vessel Plus., 2025
DOI: 10.20517/2574-1209.2025.114

Calcium ion–exchange cross-linked porous starch microparticles with improved hemostatic properties

Jianjun Zhu, Yunbo Sun, Wenzhong Sun, Zhiyun Meng, Qiaoli Shi, Xiaoxia Zhu, Hui Gan, Ruolan Gu, Zhuona Wu and Guifang Dou

International Journal of Biological Macromolecules, 2019, 134, 435
DOI: 10.1016/j.ijbiomac.2019.05.086

Hemostatic Efficacy and Biocompatibility Evaluation of a Novel Absorbable Porous Starch Hemostat

Jianjun Zhu, Zhuona Wu, Wenzhong Sun, Zhiyun Meng, Xiaoxia Zhu, Hui Gan, Ruolan Gu, Xuan Guo and Guifang Dou

Surg Innov, 2022, 29, 367
DOI: 10.1177/15533506211046100

Synergistic enhancement of hemostatic performance of mesoporous silica by hydrocaffeic acid and chitosan

Jiawen Chen, Jie Ai, Shuning Chen, Zhiyan Xu, Jinhuo Lin, Haiqing Liu and Qinhui Chen

International Journal of Biological Macromolecules, 2019, 139, 1203
DOI: 10.1016/j.ijbiomac.2019.08.091

Improved hemostatic effects by Fe3+ modified biomimetic PLLA cotton-like mat via sodium alginate grafted with dopamine

Caili Lv, Linlong Li, Zixue Jiao, Huanhuan Yan, Zongliang Wang, Zhenxu Wu, Min Guo, Yu Wang and Peibiao Zhang

Bioactive Materials, 2021, 6, 2346
DOI: 10.1016/j.bioactmat.2021.01.002

3D porous chitin sponge with high absorbency, rapid shape recovery, and excellent antibacterial activities for noncompressible wound

Yan Fang, Yuehua Xu, Zhiguo Wang, Weikang Zhou, Liyu Yan, Xianmou Fan and Haiqing Liu

Chemical Engineering Journal, 2020, 388, 124169
DOI: 10.1016/j.cej.2020.124169

Tissue factor‐loaded collagen/alginate hydrogel beads as a hemostatic agent

Chengkun Liu, Zhuang Shi, Haiyan Sun, Lili Zhao, Xiaoqiang Wang and Fang Huang

J Biomed Mater Res, 2021, 109, 1116
DOI: 10.1002/jbm.b.34774

Clotting Blood into an Adhesive Gel by Hemostatic Powder Based on Cationic/Anionic Polysaccharides and Laponite

Yan Fang, Yukai Lin, Linyu Wang, Yunxiang Weng, Qinhui Chen and Haiqing Liu

Biomacromolecules, 2024, 25, 3335
DOI: 10.1021/acs.biomac.4c00011

Chitosan-Based Microneedle Patch with Multi-Anchoring and Integrated Hemostatic Mechanisms for Highly Efficient Bleeding Control in Dynamic, Wet Intestinal Conditions

Chuchu Tang, Xianda Liu, Shuxiang Zhang, Shengjun Cheng, Wenjie Wang, Xiran Zhou, Junhan Tang, Ran Wei, Weifeng Zhao and Changsheng Zhao

Biomacromolecules, 2025, 26, 6716
DOI: 10.1021/acs.biomac.5c00979

β-Chitin fiber sponge with rapid shape recovery for efficient hemostasis

Xuan Liu, Yingying Huang, Danchun Shao, Jinhuan Tian, Lihua Li, Changren Zhou and Lu Lu

European Polymer Journal, 2025, 236, 114151
DOI: 10.1016/j.eurpolymj.2025.114151

Oxidized cellulose-based hemostatic materials

Shaohua Zhang, Jiwei Li, Shaojuan Chen, Xiying Zhang, Jianwei Ma and Jinmei He

Carbohydrate Polymers, 2020, 230, 115585
DOI: 10.1016/j.carbpol.2019.115585

Comparing two absorbable hemostatic composites produced from plant nanocellulose and bacterial nanocellulose

Lu Liu, Xuejun Zhang, Lin Chen and Feng F. Hong

Industrial Crops and Products, 2025, 223, 120249
DOI: 10.1016/j.indcrop.2024.120249

Emerging materials for hemostasis

Xiang-Fei Li, Pengpeng Lu, Hao-Ran Jia, Guofeng Li, Baofeng Zhu, Xing Wang and Fu-Gen Wu

Coordination Chemistry Reviews, 2023, 475, 214823
DOI: 10.1016/j.ccr.2022.214823

Advances in the development and optimization strategies of the hemostatic biomaterials

Yayuan Guo, Nanqiong Cheng, Hongxiao Sun, Jianing Hou, Yuchen Zhang, Du Wang, Wei Zhang and Zhuoyue Chen

Front. Bioeng. Biotechnol., 2023, 10
DOI: 10.3389/fbioe.2022.1062676

Double‐Layer Multifunctional Sponge Constructed by Gel‐Spray System and the Application in Rapid Hemostasis of Non‐Compressible Hemorrhage

Yuyan Zhang, Xiudan Wang, Jisen Li, Zhiguang Sun, Xinran Yang, Xiaoqin Guo, Haojun Fan, Jie Shi, Shike Hou and Qi Lv

Adv Healthcare Materials, 2026, 15
DOI: 10.1002/adhm.202502910

Tissue adhesives for wound closure

Bin Kong, Cheng Qi, Huan Wang, Tiantian Kong and Zhou Liu

Smart Medicine, 2023, 2
DOI: 10.1002/SMMD.20220033

Engineered hemostatic bionanocomposite of poly(lactic acid) electrospun mat and amino‐modified halloysite for potential application in wound healing

Mahsa Delyanee, Atefeh Solouk, Somaye Akbari and Morteza Daliri Joupari

Polymers for Advanced Techs, 2021, 32, 3934
DOI: 10.1002/pat.5399

Advances in the development of hemostatic biomaterials for medical application

Yong Kiel Sung, Dae Ryeong Lee and Dong June Chung

Biomater Res, 2021, 25
DOI: 10.1186/s40824-021-00239-1

Degradable porous carboxymethyl chitin hemostatic microspheres

Yong Zhao, Jiazhen Li, Fan Leng, Siyao Lv, Wei Huang, Weiqing Sun and Xulin Jiang

Journal of Biomaterials Science, Polymer Edition, 2020, 31, 1369
DOI: 10.1080/09205063.2020.1760461

A kaolin/calcium incorporated shape memory and antimicrobial chitosan-dextran based cryogel as an efficient haemostatic dressing for uncontrolled hemorrhagic wounds

Syed Muntazir Andrabi and Ashok Kumar

Biomaterials Advances, 2023, 150, 213424
DOI: 10.1016/j.bioadv.2023.213424

The effect of ethyl acetate mediated silver nanoparticles from Urtica diocia on hemostasis; in-vitro and in-vivo study

Mohammed Binsalah, Sandhanasamy Devanesan, Mohamad S. AlSalhi, Sara Nooh, Osama Al-ghamdi and Nasser Nooh

Journal of Drug Delivery Science and Technology, 2022, 76, 103840
DOI: 10.1016/j.jddst.2022.103840

Intrinsically Bioactive Cryogels Based on Platelet Lysate Nanocomposites for Hemostasis Applications

Bárbara B. Mendes, Manuel Gómez-Florit, Ana C. Araújo, Justina Prada, Pedro S. Babo, Rui M. A. Domingues, Rui L. Reis and Manuela E. Gomes

Biomacromolecules, 2020, 21, 3678
DOI: 10.1021/acs.biomac.0c00787

Utilization of Chondroitin Sulfate as an Anhydrous Proton Conductor

Masanori Yamada and Shunta Kawamura

International Journal of Electrochemical Science, 2018, 13, 12266
DOI: 10.20964/2018.12.21

A Review of Isolation, Chemical Properties, and Bioactivities of Polysaccharides from Bletilla striata

Xiaolong Ji, Mingsong Yin, Hui Nie, Yanqi Liu and Maxim P. Evstigneev

BioMed Research International, 2020, 2020
DOI: 10.1155/2020/5391379

Analysis of Safety and Effectiveness of Sodium Alginate/Poly(γ-glutamic acid) Microspheres for Rapid Hemostasis

Yun Wang, Pei Wang, Haoran Ji, Guangyu Ji, Mingsong Wang and Xiansong Wang

ACS Appl. Bio Mater., 2021, 4, 6539
DOI: 10.1021/acsabm.1c00671

Thrombin Embedded in eMPs@Thr/Sponge with Enhanced Procoagulant Ability for Uncompressible and Massive Hemorrhage Control

Wen Liu, Xiao Yang, Pengpeng Li, Feng Sang, Lina Cao, Bingxu Zhang, Zhizhen Meng, Zhaipu Ma and Changcan Shi

ACS Appl. Bio Mater., 2021, 4, 7643
DOI: 10.1021/acsabm.1c00882

Activated Platelet‐Derived Vesicles for Efficient Hemostatic Activity

Joo Hang Lee, Heesun Jung, Jihyeon Song, Eun Seo Choi, Gayeon You and Hyejung Mok

Macromolecular Bioscience, 2020, 20
DOI: 10.1002/mabi.201900338

Biomass‐Derived Multilayer‐Structured Microparticles for Accelerated Hemostasis and Bone Repair

Jia‐Ying Liu, Yang Hu, Long Li, Chao Wang, Jia Wang, Yang Li, Dafu Chen, Xiaokang Ding, Chuanan Shen and Fu‐Jian Xu

Advanced Science, 2020, 7
DOI: 10.1002/advs.202002243

Polysaccharides composite materials for rapid hemostasis

Li Zhu, Shukun Zhang, Hui Zhang, Lei Dong, Yue Cong, Shanshan Sun and Xianghong Sun

Journal of Drug Delivery Science and Technology, 2021, 66, 102890
DOI: 10.1016/j.jddst.2021.102890

Gelatin-based biomaterials and gelatin as an additive for chronic wound repair

Hongwei Cao, Jingren Wang, Zhanying Hao and Danyang Zhao

Front. Pharmacol., 2024, 15
DOI: 10.3389/fphar.2024.1398939

Wet tissue adhesive polymeric powder hydrogels for skeletal muscle regeneration

Mingyu Lee, Daun Seo, Junggeon Park, Sun Hong Lee, Jin Jeon, Woochan Kim, Jangho Kim, Hee Seok Yang and Jae Young Lee

Bioactive Materials, 2024, 40, 334
DOI: 10.1016/j.bioactmat.2024.06.017

Amphiphilic Janus cotton gauze with enhanced moisture management and blood coagulation for rapid hemostasis and wound healing

Yan Fang, Yicheng Zhang, Liping Qiu, Yuxia Zhang, Siqi Chen, Yunxiang Weng, Haiqing Liu and Qinhui Chen

International Journal of Biological Macromolecules, 2024, 276, 133826
DOI: 10.1016/j.ijbiomac.2024.133826

Bio‐Inspired In Situ Injectable Hemostatic Agent with Covalent‐Ionic Hybrid Network for Non‐Compressible Hemorrhage

Xiao‐Suan Zhou, Zedong Cai, Yu‐Yao Li, Wei He, Tang‐Rui Zhang, Si‐Yuan Zhou and Bang‐Le Zhang

Adv Healthcare Materials, 2026, 15
DOI: 10.1002/adhm.202503697

Development of self-gelling powder combining chitosan/ bentonite nanoclay/ sodium polyacrylate for rapid hemostasis: In vitro and in vivo study

Nusrat Jahan, Md Abdullah Al Fahad, Prayas Chakma Shanto, Hyeyoung Kim, Byong-Taek Lee and Sang Ho Bae

International Journal of Biological Macromolecules, 2025, 291, 139123
DOI: 10.1016/j.ijbiomac.2024.139123

Recent Advances of Natural Polysaccharide‐based Double‐network Hydrogels for Tissue Repair

Hufei Wang, Xing Wang and Decheng Wu

Chemistry An Asian Journal, 2022, 17
DOI: 10.1002/asia.202200659

Injectable Hydrogel Based on Modified Gelatin and Sodium Alginate for Soft-Tissue Adhesive

Yuhang Xing, Xueqin Qing, Hao Xia, Shiqi Hao, Haofang Zhu, Yiyan He, Hongli Mao and Zhongwei Gu

Front. Chem., 2021, 9
DOI: 10.3389/fchem.2021.744099

Cohering Plasma into Adhesive Gel by Natural Biopolymer–Nanoparticle Hybrid Powder for Efficient Hemostasis and Wound Healing

Yan Fang, Yukai Lin, Linyu Wang, Qinhui Chen, Yunxiang Weng, Caixia Sun and Haiqing Liu

ACS Appl. Mater. Interfaces, 2024, 16, 11263
DOI: 10.1021/acsami.3c17199

Multi-crosslinking hydrogels with robust bio-adhesion and pro-coagulant activity for first-aid hemostasis and infected wound healing

Chen-Yu Zou, Xiong-Xin Lei, Juan-Juan Hu, Yan-Lin Jiang, Qian-Jin Li, Yu-Ting Song, Qing-Yi Zhang, Jesse Li-Ling and Hui-Qi Xie

Bioactive Materials, 2022, 16, 388
DOI: 10.1016/j.bioactmat.2022.02.034

Tranexamic acid-loaded catechol-modified hyaluronic acid/carboxymethyl chitosan double cross-linked porous gel micropowders for rapid hemostasis and wound healing

Chen Tang, Tuhe Shi, Guohua Xu, Jingbo Yin, Shifeng Yan and Xiaogang Bao

International Journal of Biological Macromolecules, 2024, 275, 133363
DOI: 10.1016/j.ijbiomac.2024.133363

Fabrication of Herbal Hemostat Films Loaded with Medicinal Tridax Procumbenns Extracts

Trupti Sutar, Prachi Bangde, Prajakta Dandekar and Ravindra Adivarekar

Fibers Polym, 2021, 22, 2135
DOI: 10.1007/s12221-021-0808-1

A Self‐Assembly Pro‐Coagulant Powder Capable of Rapid Gelling Transformation and Wet Adhesion for the Efficient Control of Non‐Compressible Hemorrhage

Xiong‐Xin Lei, Chen‐Yu Zou, Juan‐Juan Hu, Ming‐Hui Fan, Yan‐Lin Jiang, Ming Xiong, Chen Han, Xiu‐Zhen Zhang, Ya‐Xing Li, Long‐Mei Zhao, Rong Nie, Jesse Li‐Ling and Hui‐Qi Xie

Advanced Science, 2024, 11
DOI: 10.1002/advs.202306289

Strong tissue adhesive polyelectrolyte complex powders based on low molecular weight chitosan for acute hemorrhage control

Mi Wu, Shun Mao, Xu Liu, Yunen Liu, Peifang Cong, Jianhua Lv, Huaqin Tian and Yan Zhao

International Journal of Biological Macromolecules, 2023, 248, 125755
DOI: 10.1016/j.ijbiomac.2023.125755

Modified cotton gauze with high hemostatic efficacy due to controllable hygroscopicity and wet tissue adhesiveness

Huiying Li, Shuichang Chen, Hongjian Huang, Yan Fang, Yunxiang Weng, Qinhui Chen, Xinqing Liu and Haiqing Liu

J of Applied Polymer Sci, 2024, 141
DOI: 10.1002/app.55861

This Review Recent Advances in Chitosan and Alginate‐Based Hydrogels for Wound Healing Application

Cuthbert Kibungu, Pierre P. D. Kondiah, Pradeep Kumar and Yahya E. Choonara

Front. Mater., 2021, 8
DOI: 10.3389/fmats.2021.681960

Combination of natural polyanions and polycations based on interfacial complexation for multi-functionalization of wound dressings

Shuyang Li, Liya Wang, Jue Zhang, Zijun Zhao, Weifeng Yu, Zhi Tan, Po Gao and Xingtao Chen

Front. Bioeng. Biotechnol., 2022, 10
DOI: 10.3389/fbioe.2022.1006584

Fabricating antimicrobial peptide-immobilized starch sponges for hemorrhage control and antibacterial treatment

Xiao Yang, Wen Liu, Guanghui Xi, Mingshan Wang, Bin Liang, Yifen Shi, Yakai Feng, Xiangkui Ren and Changcan Shi

Carbohydrate Polymers, 2019, 222, 115012
DOI: 10.1016/j.carbpol.2019.115012

Incorporation of mixed-dimensional palygorskite clay into chitosan/polyvinylpyrrolidone nanocomposite films for enhancing hemostatic activity

Xiaomei Wang, Bin Mu, Hong Zhang, Yan Du, Fangfang Yang and Aiqin Wang

International Journal of Biological Macromolecules, 2023, 237, 124213
DOI: 10.1016/j.ijbiomac.2023.124213

By Endowing Polyglutamic Acid/Polylysine Composite Hydrogel with Super Intrinsic Characteristics to Enhance its Wound Repair Potential

Ran Wei, Taijun Chen, Yingying Wang, Qizhen Xu, Bo Feng, Jie Weng, Wenzhen Peng and Jianxin Wang

Macromolecular Bioscience, 2021, 21
DOI: 10.1002/mabi.202000367

A Bionic Nano-Band-Aid Constructed by the Three-Stage Self-Assembly of Peptides for Rapid Liver Hemostasis

Jin Yan, Yang Wang, Xiao Li, Dongnan Guo, Zhengjun Zhou, Ge Bai, Jianhui Li, Na Huang, Jiajie Diao, Yong Li, Wangxiao He, Wenjia Liu and Kaishan Tao

Nano Lett., 2021, 21, 7166
DOI: 10.1021/acs.nanolett.1c01800

HIGHLY POROUS ALGINATE/GELATIN SPONGE FOR HEMOSTASIS OF SEVERE FEMORAL BLEEDING IN RATS

Ali Rezaie, Ahmad Mehdipour, Salar Salmanipour, Nastaran Alipour and Roya Salehi

Studies in Medical Sciences, 2023, 33, 839
DOI: 10.61186/umj.33.12.839

A Janus Gelatin Sponge with a Procoagulant Nanoparticle-Embedded Surface for Coagulopathic Hemostasis

Yu Wang, Jie Lin, Hao Fu, Bingran Yu, Guochao Zhang, Yang Hu and Fu-Jian Xu

ACS Appl. Mater. Interfaces, 2024, 16, 353
DOI: 10.1021/acsami.3c15517

Tuning Blood–Material Interactions to Generate Versatile Hemostatic Powders and Gels

Xueru Wang, Kai Yuan, Yang Su, Xiaoyue Li, Limin Meng, Nana Zhao, Yang Hu, Feng Duan and Fu‐Jian Xu

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202301945

Capillary-driven hemostatic microenvironment in oriented collagen/CMC-Ca composite scaffold for rapid hemostasis

Huawang Zhao, Naidan Zhang, Linlin Guo, Yawen Shi, Yuyi Tian, Chunlin Wen, Weilin Xu, Yan Zhuang and Hongjun Yang

Biofabrication, 2026, 18, 025003
DOI: 10.1088/1758-5090/ae4894

Polysaccharide-based hemostats: recent developments, challenges, and future perspectives

Santosh Shivaji Biranje, Jianzhong Sun, Yifei Shi, Sujie Yu, Haixin Jiao, Meng Zhang, Qianqian Wang, Jin Wang and Jun Liu

Cellulose, 2021, 28, 8899
DOI: 10.1007/s10570-021-04132-x

Cytotoxicity and hemostatic activity of chitosan/carrageenan composite wound healing dressing for traumatic hemorrhage

Santosh S. Biranje, Pallavi V. Madiwale, Kaustubh C. Patankar, Rohan Chhabra, Prachi Bangde, Prajakta Dandekar and Ravindra V. Adivarekar

Carbohydrate Polymers, 2020, 239, 116106
DOI: 10.1016/j.carbpol.2020.116106

High-strength anti-bacterial composite cryogel for lethal noncompressible hemorrhage hemostasis: Synergistic physical hemostasis and chemical hemostasis

Ying Huang, Xin Zhao, Chunbo Wang, Jueying Chen, Yuqing Liang, Zhenlong Li, Yong Han and Baolin Guo

Chemical Engineering Journal, 2022, 427, 131977
DOI: 10.1016/j.cej.2021.131977

Tailorable mechanical and degradation properties of KCl-reticulated and BDDE-crosslinked PCL/chitosan/κ-carrageenan electrospun fibers for biomedical applications: Effect of the crosslinking-reticulation synergy

Zulema Vargas-Osorio, Eduin I. González Castillo, Nurshen Mutlu, Eva Vidomanová, Martin Michálek, Dušan Galusek and Aldo R. Boccaccini

International Journal of Biological Macromolecules, 2024, 265, 130647
DOI: 10.1016/j.ijbiomac.2024.130647

An injectable antibacterial chitosan-based cryogel with high absorbency and rapid shape recovery for noncompressible hemorrhage and wound healing

Yingping Zhang, Yue Wang, Lin Chen, Jun Zheng, Xiaojing Fan, Xinglian Xu, Guanghong Zhou, Niamat Ullah and Xianchao Feng

Biomaterials, 2022, 285, 121546
DOI: 10.1016/j.biomaterials.2022.121546

A multi-crosslinking strategy of organic and inorganic compound bio-adhesive polysaccharide-based hydrogel for wound hemostasis

Peiwen Zhao, Zhendong Guo, Hao Wang, Bo Zhou, Fenglin Huang, Siyan Dong, Jing Yang, Binbin Li and Xinyu Wang

Biomaterials Advances, 2023, 152, 213481
DOI: 10.1016/j.bioadv.2023.213481

Multifunctional wound dressing for rapid hemostasis, bacterial infection monitoring and photodynamic antibacterial therapy

Hao Yang, Yuehui Liang, Jing Wang, Qingyun Li, Qunliang Li, Aixing Tang, Youyan Liu and Hai-Bo Liu

Acta Biomaterialia, 2021, 135, 179
DOI: 10.1016/j.actbio.2021.08.037

Multifunctional Chitosan Scaffold Platforms Loaded with Natural Polyphenolic Extracts for Wound Dressing Applications

Jessica Borges-Vilches, Irem Unalan, Claudio R. Aguayo, Katherina Fernández and Aldo R. Boccaccini

Biomacromolecules, 2023, 24, 5183
DOI: 10.1021/acs.biomac.3c00727

Synthesis of chitosan iodoacetamides via carbodiimide coupling reaction: Effect of degree of substitution on the hemostatic properties

Jialong Shen, Ahmed Ali Nada, Nabil Yousrie Abou-Zeid and Samuel M. Hudson

Carbohydrate Polymers, 2020, 229, 115522
DOI: 10.1016/j.carbpol.2019.115522

An ultralong hydroxyapatite nanowire aerogel for rapid hemostasis and wound healing

Yi Zheng, Wenping Ma, Zhibo Yang, Hongjian Zhang, Jingge Ma, Tian Li, Huicong Niu, Yanling Zhou, Qingqiang Yao, Jiang Chang, Yufang Zhu and Chengtie Wu

Chemical Engineering Journal, 2022, 430, 132912
DOI: 10.1016/j.cej.2021.132912

Alkylated chitosan-attapulgite composite sponge for rapid hemostasis

Xue Chen, Guoliang Yan, Ming Chen, Ping Yang and Bolin Xu

Biomaterials Advances, 2023, 153, 213569
DOI: 10.1016/j.bioadv.2023.213569

Polysaccharide Based Hemostatic Strategy for Ultrarapid Hemostasis

Yeyi Chen, Lei Wu, Pengpeng Li, Xiao Hao, Xiao Yang, Guanghui Xi, Wen Liu, Yakai Feng, Hongchao He and Changcan Shi

Macromolecular Bioscience, 2020, 20
DOI: 10.1002/mabi.201900370

A polysaccharide/chitin hydrogel wound dressing from a Periplanattica americana residue: coagulation, antioxidant activity, and wound healing properties

Xuehua Li, Xin Xiao, Yali Liu, Jie Zhou, Hanwen Hu, Tao Yang, Haimei Yuan and Qin Song

Journal of Biomaterials Science, Polymer Edition, 2023, 34, 1579
DOI: 10.1080/09205063.2023.2170676

Peptide gel, CK2-085, maintains operative field visibility during surgery

Kenji Matsushita, Rumi Kawashima, Koji Uesugi, Shinichi Usui, Hirokazu Sakaguchi, Mari Ueki, Kazuhiko Mori, Yasumasa Otori, Hideaki Okumichi, Yoshiaki Kiuchi, Chie Sotozono, Tsunehiko Ikeda, Masaru Inatani, Andrew J. Quantock, Kohji Nishida, Shota Kojima, Ryosuke Kohmoto, Yoko Ikeda, Koji Jian, Yuki Yuasa and Kaori Komatsu

Sci Rep, 2026, 16
DOI: 10.1038/s41598-026-44854-1

Synthesis and characterization of cellulose nanofibers/chitosan/cinnamon extract wound dressing with significant antibacterial and wound healing properties

Amirhosein Kefayat, Ramin Hamidi Farahani, Mohammad Rafienia, Ebrahim Hazrati and Nafiseh Hosseini Yekta

J IRAN CHEM SOC, 2022, 19, 1191
DOI: 10.1007/s13738-021-02374-x

Cellulose nonwoven fabric coated with a chitosan/hyaluronic acid composite membrane for rapid arterial hemostasis

Yonghe Wang, Yulan Wang, Jing Guo, Fucheng Guan, Xinbin Ji, Minghan Li, Qiang Yang, Jianbin Sun, Shi Feng and Jing Tao

Chemical Engineering Journal, 2024, 497, 154404
DOI: 10.1016/j.cej.2024.154404

A review on halloysite nanotube-biopolymer nanocomposites and their biomedical applications

Amirali Soleimanpour, Saeed Saber-Samandari, Majid Abdouss, Mahsa Akbarzadeh and Hossein Ali Khonakdar

European Polymer Journal, 2024, 215, 113224
DOI: 10.1016/j.eurpolymj.2024.113224

Click-Grafting of Cardanol onto Mesoporous Silica/Silver Janus Particles for Enhanced Hemostatic and Antibacterial Performance

Jiawen Chen, Kexin Chen, Qinglin Li, Guofa Dong, Jie Ai, Haiqing Liu and Qinhui Chen

ACS Appl. Bio Mater., 2020, 3, 9054
DOI: 10.1021/acsabm.0c01267

Tranexamic acid-loaded chitosan electrospun nanofibers as drug delivery system for hemorrhage control applications

Pranabesh Sasmal and Pallab Datta

Journal of Drug Delivery Science and Technology, 2019, 52, 559
DOI: 10.1016/j.jddst.2019.05.018

Injectable Hydrogel Capable of In Situ Covalent Crosslinking for Permanent Embolization

Ruosen Xie, Yu-Chung Chen, Yi Zhao, Nisakorn Yodsanit, Yuyuan Wang, Naoaki Yamamoto, Dai Yamanouchi and Shaoqin Gong

ACS Appl. Mater. Interfaces, 2021, 13, 56988
DOI: 10.1021/acsami.1c18250

Absorbable nanocomposites composed of mesoporous bioglass nanoparticles and polyelectrolyte complexes for surgical hemorrhage control

Xingtao Chen, Shuyang Li, Yonggang Yan, Jiacan Su, Dongliang Wang, Jun Zhao, Sicheng Wang and Xin Zhang

Materials Science and Engineering: C, 2020, 109, 110556
DOI: 10.1016/j.msec.2019.110556

Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application

Santosh Shivaji Biranje, Jianzhong Sun, Lu Cheng, Yu Cheng, Yifei Shi, Sujie Yu, Haixin Jiao, Meng Zhang, Xuechu Lu, Wenjia Han, Qianqian Wang, Zhen Zhang and Jun Liu

ACS Appl. Mater. Interfaces, 2022, 14, 3792
DOI: 10.1021/acsami.1c21039

Polymeric Materials for Hemostatic Wound Healing

Suvash Ghimire, Pritha Sarkar, Kasey Rigby, Aditya Maan, Santanu Mukherjee, Kaitlyn E. Crawford and Kausik Mukhopadhyay

Pharmaceutics, 2021, 13, 2127
DOI: 10.3390/pharmaceutics13122127

Construction of Hemocompatible and Histocompatible Surface by Grafting Antithrombotic Peptide ACH11 and Hydrophilic PEG

Jing Zhao, Lingchuang Bai, Khan Muhammad, Xiang-kui Ren, Jintang Guo, Shihai Xia, Wencheng Zhang and Yakai Feng

ACS Biomater. Sci. Eng., 2019, 5, 2846
DOI: 10.1021/acsbiomaterials.9b00431

Chitosan Lactate Particles for Non-Compression Hemostasis on Hepatic Resection

Yuhui Jiang, Xiaoxuan Tang, Tao Li, Jue Ling, Yifan Ge and Yumin Yang

Polymers, 2023, 15, 656
DOI: 10.3390/polym15030656

Development of a Nonwoven Hemostatic Dressing Based on Unbleached Cotton: A De Novo Design Approach

J. Vincent Edwards, Elena Graves, Nicolette Prevost, Brian Condon, Dorne Yager, Joseph Dacorta and Alvin Bopp

Pharmaceutics, 2020, 12, 609
DOI: 10.3390/pharmaceutics12070609

Cellulose nanocrystals-based materials as hemostatic agents for wound dressings: a review

Anne Carolyne Mendonça Cidreira, Karine Cappuccio de Castro, Tahmasb Hatami, Lamia Zuniga Linan and Lucia Helena Innocentini Mei

Biomed Microdevices, 2021, 23
DOI: 10.1007/s10544-021-00581-0

Chitosan-based composites reinforced with antibacterial flexible wood membrane for rapid hemostasis

Qingwu Wang, Tianyu Luo, Xiaodong Xu, Qiaoyi Han, Xin Xu, Xingxia Zhang, Xia Liu and Qiang Shi

International Journal of Biological Macromolecules, 2022, 215, 450
DOI: 10.1016/j.ijbiomac.2022.06.074

Biopharmaceutical applications of microbial polysaccharides as materials: A Review

Yige Song, Shuxin Li, Hao Gong, Ryan Chak Sang Yip and Hao Chen

International Journal of Biological Macromolecules, 2023, 239, 124259
DOI: 10.1016/j.ijbiomac.2023.124259

Study of double-bonded carboxymethyl chitosan/cysteamine-modified chondroitin sulfate composite dressing for hemostatic application

Shumin Wang, Xiaoguo Ji, Shumin Chen, Chunyue Zhang, Yibing Wang, Haodong Lin and Liming Zhao

European Polymer Journal, 2022, 162, 110875
DOI: 10.1016/j.eurpolymj.2021.110875

Advanced hydrogels for diabetic wound healing: From functionalized design, controlled preparation to application performance evaluation

Yuan Tang, Yue Zhang, Jiangpeng Ding, Jingjing Ni, Zhaowen Li, Wei Xie, Hao Wang, Xugui Li and Huaming Yang

Materials Today Communications, 2026, 52, 115102
DOI: 10.1016/j.mtcomm.2026.115102

A new boundary growth model for the analysis of microscopic blockage and various cross-section shapes effects in porous functional medical material

Junhong Hao, Xuefeng Wu, Tengyu Ma, Chenzhi Ju, Tong Hao and Wenchao Li

Front. Mater., 2024, 10
DOI: 10.3389/fmats.2023.1324106

Hydro‐Sensitive, In Situ Ultrafast Physical Self‐Gelatinizing, and Red Blood Cells Strengthened Hemostatic Adhesive Powder with Antibiosis and Immunoregulation for Wound Repair

Lingling Shang, Yonggan Yan, Zhao Li, Hong Liu, Shaohua Ge and Baojin Ma

Advanced Science, 2024, 11
DOI: 10.1002/advs.202306528

Synergistic effects of arginine and tannic acid on chitosan matrices: An approach for hemostatic sponge development

Rizos Evangelos Bikiaris, Nikolaos Iosif Matschek, Ioanna Koumentakou, Argyri Niti and George Z. Kyzas

International Journal of Biological Macromolecules, 2025, 318, 145105
DOI: 10.1016/j.ijbiomac.2025.145105

Polyvinyl alcohol/sodium alginate composite sponge with 3D ordered/disordered porous structure for rapidly controlling noncompressible hemorrhage

Pengpeng Li, Lina Cao, Feng Sang, Bingxu Zhang, Zhizhen Meng, Lingling Pan, Jiahui Hao, Xiao Yang, Zhaipu Ma and Changcan Shi

Biomaterials Advances, 2022, 134, 112698
DOI: 10.1016/j.msec.2022.112698

Advancement in fabricating precision hemostats using nanocomposites and polymeric systems: From biofunctionality to clinical translation

Ankit Majie, Santanu Ghosh and Bapi Gorain

Biomaterials Advances, 2026, 182, 214683
DOI: 10.1016/j.bioadv.2025.214683

Preparation and hemostatic evaluation of carboxymethyl chitosan/gelatin/clinodiside a composite sponges

Shuli Chen, Jie Hu, Di Zhang, Zihan Li, Zhiyun Zheng, Shuangying Gui and Ning He

Journal of Biomaterials Science, Polymer Edition, 2025, 36, 2216
DOI: 10.1080/09205063.2025.2499285

Hydrogel-Based Biomaterials Engineered from Natural-Derived Polysaccharides and Proteins for Hemostasis and Wound Healing

Junyao Cheng, Jianheng Liu, Ming Li, Zhongyang Liu, Xing Wang, Licheng Zhang and Zheng Wang

Front. Bioeng. Biotechnol., 2021, 9
DOI: 10.3389/fbioe.2021.780187

3D Printed Porous Okara-Based Sponge with Hemostatic and Antimicrobial Effects for Wound Healing

Jiawei Fang, Zhengguo Wu, Honglin Fu, Changliang Xu, Xiaoyun Li, Hansong Yu and Xiaoying Wang

ACS Sustainable Chem. Eng., 2024, 12, 11231
DOI: 10.1021/acssuschemeng.4c02407

Chitosan sponge doped with high-yield microporous carbon nanospheres for rapid hemostasis

Youjing Shi, Lijie Wang, Wei Wei, Sheng Ding, Wen Zhang, Fan Li, Zhaoming Li and Xin Meng

International Journal of Biological Macromolecules, 2025, 317, 144838
DOI: 10.1016/j.ijbiomac.2025.144838

Can bleeding in trabeculectomy be decreased? Effectiveness of brimonidine pre-treatment

Fikret Ucar and Halil İbrahim Yener

European Journal of Ophthalmology, 2022, 32, 3476
DOI: 10.1177/11206721221080621

A self-gelling powder based on polyacrylic acid/polyacrylamide/quaternate chitosan for rapid hemostasis

Zhouying Tan, Xi Li, Chaojie Yu, Mengmeng Yao, Zhongming Zhao, Bingyan Guo, Lei Liang, Yuping Wei, Fanglian Yao, Hong Zhang and Junjie Li

International Journal of Biological Macromolecules, 2023, 232, 123449
DOI: 10.1016/j.ijbiomac.2023.123449

Chitosan-Based Hemostatic Hydrogels: The Concept, Mechanism, Application, and Prospects

Peng Fan, Yanbo Zeng, Dionisio Zaldivar-Silva, Lissette Agüero and Shige Wang

Molecules, 2023, 28, 1473
DOI: 10.3390/molecules28031473

Nanocomposite hydrogel based on carrageenan-coated starch/cellulose nanofibers as a hemorrhage control material

Shima Tavakoli, Mahshid Kharaziha, Shervin Nemati and Ali Kalateh

Carbohydrate Polymers, 2021, 251, 117013
DOI: 10.1016/j.carbpol.2020.117013

Serotonin-functionalized starch-based hemostatic sponges enhance platelet activation in the management of non-compressible hemorrhage

Juan Wu, Zhenhua Huang, Dong Zhang, Laiqiang Tong, Fan Gao, Fangping Chen and Changsheng Liu

International Journal of Biological Macromolecules, 2024, 283, 137547
DOI: 10.1016/j.ijbiomac.2024.137547

Conductive adhesive self-healing nanocomposite hydrogel wound dressing for photothermal therapy of infected full-thickness skin wounds

Jiahui He, Mengting Shi, Yongping Liang and Baolin Guo

Chemical Engineering Journal, 2020, 394, 124888
DOI: 10.1016/j.cej.2020.124888

Fabrication of Hydroxypropyl Chitosan/Soy Protein Isolate Hydrogel for Effective Hemorrhage Control

Yanan Zhao, Ao Xiao, Ping Wu, Feixiang Chen, Qiang Zhang, Xiao Liang, Xinwei Han, Xiaowen Shi, Yinping Li and Yun Chen

Tissue Engineering Part A, 2021, 27, 788
DOI: 10.1089/ten.tea.2020.0174

Hemostatic, antibacterial, conductive and vascular regenerative integrated cryogel for accelerating the whole wound healing process

Jiaxin Wang, Jiahui He, Yutong Yang, Xianzhen Jin, Juntang Li and Baolin Guo

Chemical Engineering Journal, 2024, 479, 147577
DOI: 10.1016/j.cej.2023.147577

Recent progress in polysaccharide microsphere-based hemostatic material for intravascular and extravascular hemostasis: A review

Fan Leng, Jie Liu, Enfu Du, Sai Lei, Cong Xie, Xulin Jiang and Tong-fei Li

International Journal of Biological Macromolecules, 2025, 300, 140280
DOI: 10.1016/j.ijbiomac.2025.140280

Computational Screening of Phytochemicals in Eupatorium adenophorum Extracts for Modulating Blood Coagulation: A Pharmacoinformatics Study

Sushmita Dwivedi and Mamta Baunthiyal

LOC, 2025, 22, 532
DOI: 10.2174/0115701786334548241226094122

Chitosan-based antibacterial hemostatic sponge for uncontrollable tooth extraction bleeding in anticoagulated patients

Rongxia Tang, Lu Zheng, Shangfei Chi, Lu Wei, Xiaoying Wang and Xiao Ma

Colloids and Surfaces B: Biointerfaces, 2026, 259, 115325
DOI: 10.1016/j.colsurfb.2025.115325

Ultrafast Self‐Gelling and Wet Adhesive Powder for Acute Hemostasis and Wound Healing

Xin Peng, Xiao Xu, Yingrui Deng, Xian Xie, Limei Xu, Xiayi Xu, Weihao Yuan, Boguang Yang, Xuefeng Yang, Xianfeng Xia, Li Duan and Liming Bian

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202102583

Hemostatic materials in wound care

Peiyu Yu and Wen Zhong

Burns & Trauma, 2021, 9
DOI: 10.1093/burnst/tkab019

Recent advances in biopolymer-based hemostatic materials

Marvin Mecwan, Jinghang Li, Natashya Falcone, Menekse Ermis, Emily Torres, Ramon Morales, Alireza Hassani, Reihaneh Haghniaz, Kalpana Mandal, Saurabh Sharma, Surjendu Maity, Fatemeh Zehtabi, Behnam Zamanian, Rondinelli Herculano, Mohsen Akbari, Johnson V. John and Ali Khademhosseini

Regenerative Biomaterials, 2022, 9
DOI: 10.1093/rb/rbac063

Clays and Wound Healing

Guangjian Tian, Zhou Wang, Zongwang Huang, Zuyan Xie, Lu Xia and Yi Zhang

Materials, 2024, 17, 1691
DOI: 10.3390/ma17071691

The Effect of Citric Acid on Crosslinking Behavior, Hemostasis, Calcium Ion Release, Swelling, and Cytotoxicity of Gelatin/Monetite Sponge for Dental Hemostatic Applications

Fatimah Az‐Zahra Mardiati Putri, Azizah Intan Pangesty, Sunarso Sunarso and Myrna Nurlatifah Zakaria

J of Applied Polymer Sci, 2026, 143
DOI: 10.1002/app.70302

Rapid hemostasis accompanied by antibacterial action of calcium crosslinking tannic acid-coated mesoporous silica/silver Janus nanoparticles

Jiawen Chen, Liping Qiu, Qinglin Li, Jie Ai, Haiqing Liu and Qinhui Chen

Materials Science and Engineering: C, 2021, 123, 111958
DOI: 10.1016/j.msec.2021.111958

The recent research progress of polyphenol‐derived biomaterials in wound repair

Shuya Zhao, Lu Han, Liwei Yan and Xiong Lu

Biosurface and Biotribology, 2023, 9, 114
DOI: 10.1049/bsb2.12074

Multifunctional Oxidized Dextran Cross-Linked Alkylated Chitosan/Drug-Loaded and Silver-Doped Mesoporous Bioactive Glass Cryogel for Hemostasis of Noncompressible Wounds

Dong Lei, Jing Zhao, Chenhui Zhu, Min Jiang, Pei Ma, Yu Mi and Daidi Fan

Gels, 2023, 9, 455
DOI: 10.3390/gels9060455

Emerging horizons and prospects of polysaccharide-constructed gels in the realm of wound healing

Shen-Han Wu, Lekshmi Rethi, Wen-Yu Pan, Hieu Trung Nguyen and Andrew E.-Y. Chuang

Colloids and Surfaces B: Biointerfaces, 2024, 235, 113759
DOI: 10.1016/j.colsurfb.2024.113759

Antioxidative bioactive glass reinforced injectable hydrogel with reactive oxygen species scavenging capacity for diabetic wounds treatment

Hao Chang, Pengfei Tian, Liuzhi Hao, Chengwei Hu, Bo Liu, Fengzhen Meng, Xin Yi, Xiaohua Pan, Xiaohua Hu, Huan Wang, Xinyun Zhai, Xu Cui, Jason Pui Yin Cheung, Xuanyong Liu, Haobo Pan, Shaoquan Bian and Xiaoli Zhao

Chemical Engineering Journal, 2024, 481, 148768
DOI: 10.1016/j.cej.2024.148768

Biodegradable Microporous Starch with Assembled Thrombin for Rapid Induction of Hemostasis

Qing Li, Fei Lu, Songmin Shang, Hongli Ye, Kun Yu, Bitao Lu, Yang Xiao, Fangyin Dai and Guangqian Lan

ACS Sustainable Chem. Eng., 2019, 7, 9121
DOI: 10.1021/acssuschemeng.8b05701

Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing

Xinchen Du, Le Wu, Hongyu Yan, Zhuyan Jiang, Shilin Li, Wen Li, Yanli Bai, Hongjun Wang, Zhaojun Cheng, Deling Kong, Lianyong Wang and Meifeng Zhu

Nat Commun, 2021, 12
DOI: 10.1038/s41467-021-24972-2

Gelatin Methacryloyl-Based Sponge with Designed Conical Microchannels for Rapidly Controlling Hemorrhage and Theoretical Verification

Lina Cao, Zhixiao Ji, Bingxu Zhang, Xiaoqin Si, Yuzhen Wang, Jiahui Hao, Xujian Li, Weihua Mu, Xiao Yang and Changcan Shi

ACS Biomater. Sci. Eng., 2023, 9, 2001
DOI: 10.1021/acsbiomaterials.3c00161

Recent Advances in Polysaccharide-Based Hydrogels for Tumor Immunotherapy

Youxi Zhou, Kaizhao Chen, Hongwei Cheng and Shuaishuai Zhang

Gels, 2025, 11, 152
DOI: 10.3390/gels11030152

Biocompatible Hemostatic Sponge Exhibiting Broad-Spectrum Antibacterial Activity

Brinta Bhattacharjee, Riya Mukherjee and Jayanta Haldar

ACS Biomater. Sci. Eng., 2022, 8, 3596
DOI: 10.1021/acsbiomaterials.2c00410

Modified alginate-based soft tissue adhesive: Synthesis, characterization, and application in the treatment of in vivo wound closure

Masud Rana, Md. Tamzid Hossain Molla, Md. Dipu Malitha, Dipesh Chandra, Md. Abul Bashar, Tapan Kumar Biswas, Most. Arifa Sultana and Md. Shameem Ahsan

International Journal of Adhesion and Adhesives, 2023, 127, 103515
DOI: 10.1016/j.ijadhadh.2023.103515

Recent progress in surgical adhesives for biomedical applications

Kaikai Zheng, Qinhao Gu, Dong Zhou, Muran Zhou and Lei Zhang

Smart Materials in Medicine, 2022, 3, 41
DOI: 10.1016/j.smaim.2021.11.004

Multifunctional nanofibrous scaffolds for enhancing full-thickness wound healing loaded with Bletilla striata polysaccharides

Chaoyue Zhao, Long Huang, Jie Tang, Linlin Lv, Xinying Wang, Xiyao Dong, Fengrui Yang and Qingxiang Guan

International Journal of Biological Macromolecules, 2024, 278, 134597
DOI: 10.1016/j.ijbiomac.2024.134597

Injectable Ca/ε-aminocaproic acid/dextran phosphate hydrogel for effective acute bleeding control

Uladzislau E. Aharodnikau, Yulia I. Pristromova, Pavel M. Bychkovsky, Andrei I. Aslauski, Alena A. Khiliuta, Yu Cai, Anastasiya V. Baranouskaya, Aliaksandra V. Yedchyk, Daria A. Salamevich, Yanfang Sun, Maryia A. Shauchenka, Alesia V. Panibrat, Matsvei V. Kisliuk, Anhelina G. Karcheuskaya, Tatiana L. Yurkshtovich, Guohua Jiang, Wenliang Song and Sergey O. Solomevich

International Journal of Biological Macromolecules, 2025, 310, 143444
DOI: 10.1016/j.ijbiomac.2025.143444

Recent progress of collagen-based hydrogels for wound healing: a review

Hongyu Jin, Kun Huang, Rong Zhou, Pengwen Chen, Man Zhang and Yong Jin

Collagen & Leather, 2026, 8
DOI: 10.1186/s42825-025-00225-6

Graphene-ophicalcite heterogeneous composite sponge for rapid hemostasis

Bingxin Wu, Fanglin Du, Wenjing A, Fang Liu, Yichun Liu, Weitao Zheng, Guofeng Li and Xing Wang

Colloids and Surfaces B: Biointerfaces, 2022, 216, 112596
DOI: 10.1016/j.colsurfb.2022.112596

Water-driven noninvasively detachable wet tissue adhesives for wound closure

Hongjian Huang, Renfeng Xu, Peng Ni, Zhenghong Zhang, Caixia Sun, Huaying He, Xinyue Wang, Lidan Zhang, Ziyi Liang and Haiqing Liu

Materials Today Bio, 2022, 16, 100369
DOI: 10.1016/j.mtbio.2022.100369

Hemostasis Strategies and Recent Advances in Hydrogels for Managing Uncontrolled Hemorrhage

Lijun Liu, Rui Jing, Lei Yao, Yanbo Wang, Lihua Mu and Yuan Hu

ACS Appl. Bio Mater., 2025, 8, 42
DOI: 10.1021/acsabm.4c01221

Preparation and characterization of tissue-factor-loaded alginate: Toward a bioactive hemostatic material

Chengkun Liu, Zhuang Shi, Haiyan Sun, Christopher J. Mujuni, Lili Zhao, Xiaoqiang Wang and Fang Huang

Carbohydrate Polymers, 2020, 249, 116860
DOI: 10.1016/j.carbpol.2020.116860

Hydrogen-Bonding Crosslinked Supramolecular Polymer Materials: From Design Evolution of Side-Chain Hydrogen-Bonding to Applications

Qian Zhang, Zi-Yang Xu and Wen-Guang Liu

Chin J Polym Sci, 2024, 42, 1619
DOI: 10.1007/s10118-024-3204-7

Thrombin‐Anchored Bacterial Cellulose Dressing for Advanced Burn Wound Care

Yaomin Wang, Peilang Yang, Yanyi Wang, Shaojie Chen, Kesheng Gan, Shan Ma, Jiaao Yu, Yan Liu, Bolin An and Chao Zhong

Advanced Materials, 2025, 37
DOI: 10.1002/adma.202420338

Chitosan-based hemostatic sponges as new generation hemostatic materials for uncontrolled bleeding emergency: Modification, composition, and applications

Zhicheng Liu, Yanzi Xu, Huining Su, Xunan Jing, Daquan Wang, Shaohui Li, Yang Chen, Hao Guan and Lingjie Meng

Carbohydrate Polymers, 2023, 311, 120780
DOI: 10.1016/j.carbpol.2023.120780

A Review on Electrospun Poly(amino acid) Nanofibers and Their Applications of Hemostasis and Wound Healing

Yuexin Ji, Wenliang Song, Lin Xu, Deng-Guang Yu and Sim Wan Annie Bligh

Biomolecules, 2022, 12, 794
DOI: 10.3390/biom12060794

Antibacterial and rapidly absorbable hemostatic sponge by aldehyde modification of natural polysaccharide

Jinrun Zhang, Zenghui Chen, Dejie Zeng, Yuman Xia, Yizhuo Fan, Xinyu Zhang, Nan Li, Xiaofen Liu, Xiaqing Sun, Shibing Zhao, Jianfa Zhang, Junhao Liu and Qi Sun

Commun Mater, 2024, 5
DOI: 10.1038/s43246-024-00579-0

Porous Sodium Carboxymethyl Starch Microspheres for Hemostasis and Skin Wound Healing

Qing Zhou, Wenjie Chen, Han Wang, Cuicui Wu, Qianqian Zhu, Lei Luo, Xiao Zheng, Chenglong Yu, Aijun Guo, Jianjin Wang and Shunqing Tang

ACS Appl. Bio Mater., 2025, 8, 3076
DOI: 10.1021/acsabm.4c01933

Peptide-immobilized starch/PEG sponge with rapid shape recovery and dual-function for both uncontrolled and noncompressible hemorrhage

Xiao Yang, Wen Liu, Yifen Shi, Guanghui Xi, Mingshan Wang, Bin Liang, Yakai Feng, Xiangkui Ren and Changcan Shi

Acta Biomaterialia, 2019, 99, 220
DOI: 10.1016/j.actbio.2019.08.039

A hemoadhican-based sponge with anti-heparin interference for treating uncontrollable massive hemorrhage

Rui Fang, Ning Yu, Fa Wang, Zhao Ding, Xi Xu and Jianfa Zhang

International Journal of Biological Macromolecules, 2024, 279, 135097
DOI: 10.1016/j.ijbiomac.2024.135097

Antimicrobial Peptides and Macromolecules for Combating Microbial Infections: From Agents to Interfaces

Luofeng Yu, Kunpeng Li, Jing Zhang, Haoyu Jin, Atif Saleem, Qing Song, Qingyan Jia and Peng Li

ACS Appl. Bio Mater., 2022, 5, 366
DOI: 10.1021/acsabm.1c01132

Co-immobilization of ACH11 antithrombotic peptide and CAG cell-adhesive peptide onto vascular grafts for improved hemocompatibility and endothelialization

Jing Zhao, Lingchuang Bai, Xiang-kui Ren, Jintang Guo, Shihai Xia, Wencheng Zhang and Yakai Feng

Acta Biomaterialia, 2019, 97, 344
DOI: 10.1016/j.actbio.2019.07.057

Strongly-adhesive easily-detachable carboxymethyl cellulose aerogel for noncompressible hemorrhage control

Siwen Pan, Yige Li, Xinru Tong, Lei Chen, Li Wang, Tao Li and Qiang Zhang

Carbohydrate Polymers, 2023, 301, 120324
DOI: 10.1016/j.carbpol.2022.120324

Hemoadhican, a Tissue Adhesion Hemostatic Material Independent of Blood Coagulation

Changchang Kong, Shijunyin Chen, Xianjin Wang, Chengtao Hu, Bing Li, Renjie Fu and Jianfa Zhang

Adv Healthcare Materials, 2023, 12
DOI: 10.1002/adhm.202300705

Facile synthesis of rapid hemostatic powder based on sodium alginate for promoting hemostasis and wound healing

Aihong Chen, Lixue Wu, Kaiyang Wang, Long Qin, Kexin Zhang, Song Chen, Yijiong Zhang, Wei Song, Qian Zhang, Wei Xia, Yu Luo, Xijian Liu and Jian Wan

International Journal of Biological Macromolecules, 2025, 308, 142728
DOI: 10.1016/j.ijbiomac.2025.142728

Composites Based on Gellan Gum, Alginate and Nisin-Enriched Lipid Nanoparticles for the Treatment of Infected Wounds

Katarzyna Reczyńska-Kolman, Kinga Hartman, Konrad Kwiecień, Monika Brzychczy-Włoch and Elżbieta Pamuła

IJMS, 2021, 23, 321
DOI: 10.3390/ijms23010321

Aloesin-loaded chitosan/cellulose-based scaffold promotes skin tissue regeneration

Aasia Hameed, Mehreen Tariq, Sobia Sadia, M. Rizwan Alam, Adnan Haider and Hussain Mustatab Wahedi

International Journal of Biological Macromolecules, 2024, 273, 133030
DOI: 10.1016/j.ijbiomac.2024.133030

Smart nano-in-microparticles to tackle bacterial infections in skin tissue engineering

Marco Ruggeri, Barbara Vigani, Cinzia Boselli, Antonia Icaro Cornaglia, Daniele Colombo, Rita Sànchez-Espejo, Elena Del Favero, Narcisa Mandras, Janira Roana, Lorenza Cavallo, Laura Cantù, Cesar Viseras, Silvia Rossi and Giuseppina Sandri

Materials Today Bio, 2022, 16, 100418
DOI: 10.1016/j.mtbio.2022.100418

Polysaccharide-based hydrogel promotes skin wound repair and research progress on its repair mechanism

Shuai Zhang, Hongyuan Liu, Wei Li, Xinglong Liu, Lina Ma, Ting Zhao, Qiteng Ding, Chuanbo Ding and Wencong Liu

International Journal of Biological Macromolecules, 2023, 248, 125949
DOI: 10.1016/j.ijbiomac.2023.125949

Coagulating blood into adhesive gel by hybrid powder based on oppositely charged polysaccharide/tannic acid-modified mesoporous bioactive glass

Yan Fang, Yukai Lin, Linyu Wang, Xinwei Zheng, Qinhui Chen, Yunxiang Weng and Haiqing Liu

International Journal of Biological Macromolecules, 2024, 270, 132440
DOI: 10.1016/j.ijbiomac.2024.132440

Fabrication of Hydrophobic Laponite Nanoclay‐Loaded Polycaprolactone Electrospun Membranes for Hemostatic Applications

Thong Lam Vu, Tin Anh Tran, Khoi Minh Le, My‐An Tran Le, Vo Minh Quan, Phu Phong Vo, Kieu Thi‐Thuy Nguyen, Han Thi Ngoc To, Thi‐Hiep Nguyen and Hoan Ngoc Doan

Polymer Engineering & Sci, 2026
DOI: 10.1002/pen.70489

Construction of Nanoparticle-Enhanced Multimodular Hemostatic Sponges and Their Application in Multiple Bleeding Scenarios

Ye Wu, Heng Gong, Xuekun Yang, Xikun Ma, Biao Cao, Chen Chen, Tingjiang Gan, Changyuan He, Xiangtian Deng, Yaxing Li, Runfang Fu, Bin Yan and Hui Zhang

ACS Appl. Mater. Interfaces, 2026
DOI: 10.1021/acsami.6c04469

Recent advances in the application of clay-containing hydrogels for hemostasis and wound healing

Xiaojuan Huang, Bin Hu, Xinyuan Zhang, Peng Fan, Zheng Chen and Shige Wang

Expert Opinion on Drug Delivery, 2024, 21, 457
DOI: 10.1080/17425247.2024.2329641

Zeolite firmly anchored regenerated cellulose aerogel for efficient and biosafe hemostasis

Zhiping Jin, Lei Chen, Xiaodi Liu, Ruicai Xia, Wei Li, Guodong Wang and Qiang Zhang

International Journal of Biological Macromolecules, 2025, 304, 140743
DOI: 10.1016/j.ijbiomac.2025.140743

Stimuli-Responsive Polysaccharide Hydrogels and Their Composites for Wound Healing Applications

Maria Psarrou, Anna Mitraki, Maria Vamvakaki and Chrysoula Kokotidou

Polymers, 2023, 15, 986
DOI: 10.3390/polym15040986

A Comparison of Hemostatic Activities of Zeolite-Based Formulary Finishes on Cotton Dressings

J. Vincent Edwards, Nicolette T. Prevost and Michael Santiago Cintron

JFB, 2023, 14, 255
DOI: 10.3390/jfb14050255

Vancomycin and nisin-modified magnetic Fe3O4@SiO2 nanostructures coated with chitosan to enhance antibacterial efficiency against methicillin resistant Staphylococcus aureus (MRSA) infection in a murine superficial wound model

Mona Nasaj, Abbas Farmany, Leili Shokoohizadeh, Farid Aziz Jalilian, Reza Mahjoub, Ghodratollah Roshanaei, Alireza Nourian, Omid Heydari Shayesteh and Mohammadreza Arabestani

BMC Chemistry, 2024, 18
DOI: 10.1186/s13065-024-01129-y