Design, characterization and pharmaceutical/pharmacological applications of ibuprofen conjugates based on hydroxyethylcellulose

Khawar Abbas, Muhammad Amin, Muhammad Ajaz Hussain, Muhammad Sher, Syed Nasir Abbas Bukhari and Kevin J. Edgar

RSC Adv., 2017, 7, 50672
DOI: 10.1039/C7RA08502H

Hydroxyethyl starch based smart nanomedicine

Huimin Wang, Hang Hu, Hai Yang and Zifu Li

RSC Adv., 2021, 11, 3226
DOI: 10.1039/D0RA09663F

iRGD-decorated reduction-responsive nanoclusters for targeted drug delivery

Hang Hu, Jiangling Wan, Xuetao Huang, Yuxiang Tang, Chen Xiao, Huibi Xu, Xiangliang Yang and Zifu Li

Nanoscale, 2018, 10, 10514
DOI: 10.1039/C8NR02534G

Folate-conjugated and pH-triggered doxorubicin and paclitaxel co-delivery micellar system for targeted anticancer drug delivery

Lijing Niu, Feiyan Zhu, Bowen Li, Lingling Zhao, Hongze Liang, Yinghua Yan and Hui Tan

Mater. Chem. Front., 2018, 2, 1529
DOI: 10.1039/C8QM00217G

Prodrugs in Combination with Nanocarriers as a Strategy for Promoting Antitumoral Efficiency

Ming-Hsien Lin, Chi-Feng Hung, Ching-Yun Hsu, Zih-Chan Lin and Jia-You Fang

Future Med. Chem., 2019, 11, 2131
DOI: 10.4155/fmc-2018-0388

α-Amylase- and Redox-Responsive Nanoparticles for Tumor-Targeted Drug Delivery

Yihui Li, Hang Hu, Qing Zhou, Yanxiao Ao, Chen Xiao, Jiangling Wan, Ying Wan, Huibi Xu, Zifu Li and Xiangliang Yang

ACS Appl. Mater. Interfaces, 2017, 9, 19215
DOI: 10.1021/acsami.7b04066

Redox-responsive micelles for triggered drug delivery and effective laryngopharyngeal cancer therapy

Changling Sun, Xiaoying Li, Xiaodong Du and Teng Wang

International Journal of Biological Macromolecules, 2018, 112, 65
DOI: 10.1016/j.ijbiomac.2018.01.136

Full-profile bioanalysis of polydisperse macromolecular hydroxyethyl starch 130/0.4 in rat plasma via LC-IS-CID coupled with MRM

Xin Xu, Huan Yang, Jiachong Chi, Xiangjun Meng and Jingkai Gu

Chinese Chemical Letters, 2026, 37, 111703
DOI: 10.1016/j.cclet.2025.111703

Structural Aspect of Hydroxyethyl-Starch–Anticancer-Drug-Conjugates as State-of-the-Art Drug Carriers

Koushik Chandra, Sansa Dutta, Haradhan Kolya and Chun-Won Kang

Sci. Pharm., 2023, 91, 32
DOI: 10.3390/scipharm91030032

RETRACTED: Repeated dose 28-day oral toxicity study of DEAE-Dextran in mice: An advancement in safety chemotherapeutics

Anita K. Bakrania, Bhavesh C. Variya, Prem Madan and Snehal S. Patel

Regulatory Toxicology and Pharmacology, 2017, 88, 262
DOI: 10.1016/j.yrtph.2017.07.005

Doxorubicin-galactomannan nanoconjugates for potential cancer treatment

Laís Ramos Monteiro de Lima, Maria Francilene Souza Silva, Gisele S. Araújo, Fábio de Oliveira Silva Ribeiro, Irisvan S. Ribeiro, Cláudia Pessoa, Raimundo N. Costa Filho, José Delano B. Marinho Filho, Ana Jersia Araújo, Durcilene Alves da Silva, Judith P. Andrade Feitosa and Regina Celia Monteiro de Paula

Carbohydrate Polymers, 2024, 342, 122356
DOI: 10.1016/j.carbpol.2024.122356

Biobased Magnetic Microspheres Containing Aldehyde Groups: Constructed by Vanillin-Derived Polymethacrylate/Fe3O4 and Recycled in Adsorbing Amine

Huanyu Zhang, Jianping Deng and Youping Wu

ACS Sustainable Chem. Eng., 2017, 5, 658
DOI: 10.1021/acssuschemeng.6b02018

Dual-acidity-labile polysaccharide-di-drugs conjugate for targeted cancer chemotherapy

Di Li, Tianqi Su, Lili Ma, Feng Yin, Weiguo Xu, Jianxun Ding and Zigang Li

European Journal of Medicinal Chemistry, 2020, 199, 112367
DOI: 10.1016/j.ejmech.2020.112367

A review of carbohydrate polymer-synthesized nanoparticles in cancer immunotherapy: Past, present and future perspectives

Chunyan Wang, Xueyao Zhang, Qiaobei Li, Yuxin Hou, Minglu Sun, Jun Sun, Zhe Lou, Xu Han and Yinyan Li

International Journal of Biological Macromolecules, 2025, 286, 138195
DOI: 10.1016/j.ijbiomac.2024.138195

Hydroxyethyl Starch-Based Functionalization of Gold Nanorods: A Possible Alternative to Polyethylene Glycol as a Surface Modifier

Asmita Pandey, Sujan Khadka, Ying Wan and Marinella Striccoli

Journal of Nanomaterials, 2021, 2021, 1
DOI: 10.1155/2021/5555448

Investigating the electrostatic complexation of BCNO nanoparticles with a stimuli-responsive double hydrophilic graft copolymer

Yun-Chen Chien, You-Teng Hsu, Chen-Wei Chiang, Pei Yuin Keng and Tzu-Wei Wang

Giant, 2023, 14, 100162
DOI: 10.1016/j.giant.2023.100162

Co-delivery nanoparticle to overcome metastasis promoted by insufficient chemotherapy

Qing Zhou, Yihui Li, Yanhong Zhu, Chan Yu, Haibo Jia, Binghao Bao, Hang Hu, Chen Xiao, Jianqi Zhang, Xiaofan Zeng, Ying Wan, Huibi Xu, Zifu Li and Xiangliang Yang

Journal of Controlled Release, 2018, 275, 67
DOI: 10.1016/j.jconrel.2018.02.026

Construction of doxorubicin-conjugated lentinan nanoparticles for enhancing the cytotoxocity effects against breast cancer cells

Ying Wang, Jingwen Chen, Qianqian Han, Qiang Luo, Hongmei Zhang and Yanqing Wang

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2019, 579, 123657
DOI: 10.1016/j.colsurfa.2019.123657

pH-Sensitive nanoparticles based on amphiphilic imidazole/cholesterol modified hydroxyethyl starch for tumor chemotherapy

Zhilang Xu, Die Yang, Tao Long, Lun Yuan, Shi Qiu, Defu Li, Changdao Mu and Liming Ge

Carbohydrate Polymers, 2022, 277, 118827
DOI: 10.1016/j.carbpol.2021.118827

Flurbiprofen conjugates based on hydroxyethylcellulose: Synthesis, characterization, pharmaceutical and pharmacological applications

Khawar Abbas, Muhammad Ajaz Hussain, Syed Nasir Abbas Bukhari, Muhammad Amin, Muhammad Nawaz Tahir and Sheshanath V. Bhosale

Arabian Journal of Chemistry, 2020, 13, 2101
DOI: 10.1016/j.arabjc.2018.03.011

One-Step Synthesis of Targeted Acid-Labile Polysaccharide Prodrug for Efficiently Intracellular Drug Delivery

Di Li, Xiangru Feng, Li Chen, Jianxun Ding and Xuesi Chen

ACS Biomater. Sci. Eng., 2018, 4, 539
DOI: 10.1021/acsbiomaterials.7b00856

Design of cellulose ether-based macromolecular prodrugs of ciprofloxacin for extended release and enhanced bioavailability

Muhammad Amin, Nazia Shahana Abbas, Muhammad Ajaz Hussain, Muhammad Sher and Kevin J. Edgar

International Journal of Biological Macromolecules, 2018, 113, 719
DOI: 10.1016/j.ijbiomac.2018.02.142

Hydroxyethyl starch stabilized polydopamine nanoparticles for cancer chemotherapy

Honglian Wu, Hang Hu, Jiangling Wan, Yaming Li, Yuxin Wu, Yuxiang Tang, Chen Xiao, Huibi Xu, Xiangliang Yang and Zifu Li

Chemical Engineering Journal, 2018, 349, 129
DOI: 10.1016/j.cej.2018.05.082

Schiff base bond-linked polysaccharide–doxorubicin conjugate for upregulated cancer therapy

Xiangru Feng, Di Li, Jiandong Han, Xiuli Zhuang and Jianxun Ding

Materials Science and Engineering: C, 2017, 76, 1121
DOI: 10.1016/j.msec.2017.03.201

ROMP synthesis of benzaldehyde-containing amphiphilic block polynorbornenes used to conjugate drugs for pH-responsive release

Guirong Qiu, Li Zhao, Xiong Liu, Qiuxia Zhao, Fangfei Liu, Yue Liu, Yewu Liu and Haibin Gu

Reactive and Functional Polymers, 2018, 128, 1
DOI: 10.1016/j.reactfunctpolym.2018.03.010

Targeted hydroxyethyl starch prodrug for inhibiting the growth and metastasis of prostate cancer

Kaidong Zhao, Di Li, Weiguo Xu, Jianxun Ding, Weiqian Jiang, Mingqiang Li, Chunxi Wang and Xuesi Chen

Biomaterials, 2017, 116, 82
DOI: 10.1016/j.biomaterials.2016.11.030

Recent advances in pH/enzyme-responsive polysaccharide-small-molecule drug conjugates as nanotherapeutics

Yasir Faraz Abbasi, Hriday Bera, Dongmei Cun and Mingshi Yang

Carbohydrate Polymers, 2023, 312, 120797
DOI: 10.1016/j.carbpol.2023.120797

Targeted antigen delivery to dendritic cell via functionalized alginate nanoparticles for cancer immunotherapy

Chuangnian Zhang, Gaona Shi, Ju Zhang, Huijuan Song, Jinfeng Niu, Shengbin Shi, Pingsheng Huang, Yanming Wang, Weiwei Wang, Chen Li and Deling Kong

Journal of Controlled Release, 2017, 256, 170
DOI: 10.1016/j.jconrel.2017.04.020

A Photolysis-Assist Molecular Communication for Tumor Biosensing

Yue Sun, Huafeng Bian and Yifan Chen

Sensors, 2022, 22, 2495
DOI: 10.3390/s22072495

Progress on hydroxyethyl starch-based smart nanomedicines

Yi Zhao, Zhijie Zhang, Xiangliang Yang and Zifu Li

Precision Medicine and Engineering, 2025, 2, 100041
DOI: 10.1016/j.preme.2025.100041

Starch‐based nanoparticles: Stimuli responsiveness, toxicity, and interactions with food components

Mengting Yu, Na Ji, Yanfei Wang, Lei Dai, Liu Xiong and Qingjie Sun

Comp Rev Food Sci Food Safe, 2021, 20, 1075
DOI: 10.1111/1541-4337.12677

Platinum (II)-coordinated Portulaca oleracea polysaccharides as metal-drug based polymers for anticancer study

Qianqian Han, Lirong Huang, Ying Wang, Shixin Sun, Hao Huang, Fei Li, Fangtian Wang, Ligen Chen, Hongmei Zhang and Yanqing Wang

Colloids and Surfaces B: Biointerfaces, 2021, 201, 111628
DOI: 10.1016/j.colsurfb.2021.111628

Advances in research on preparation, characterization, interaction with proteins, digestion and delivery systems of starch-based nanoparticles

Chao Qiu, Chenxi Wang, Chen Gong, David Julian McClements, Zhengyu Jin and Jinpeng Wang

International Journal of Biological Macromolecules, 2020, 152, 117
DOI: 10.1016/j.ijbiomac.2020.02.156

Designing novel bioconjugates of hydroxyethyl cellulose and salicylates for potential pharmaceutical and pharmacological applications

Khawar Abbas, Muhammad Amin, Muhammad Ajaz Hussain, Muhammad Sher, Syed Nasir Abbas Bukhari, Ibrahim Jantan and Kevin J. Edgar

International Journal of Biological Macromolecules, 2017, 103, 441
DOI: 10.1016/j.ijbiomac.2017.05.061

Autonomous In Vivo Computation in Internet of Nano Bio Things

Muhammad Ali, Yifan Chen and Michael J. Cree

IEEE Internet Things J., 2022, 9, 6134
DOI: 10.1109/JIOT.2021.3111089

Targeted Delivery of Anticancer Therapeutics with Polymers by Harnessing Tumor Microenvironment Acidity

Jiahao Shi, Bin Ma, Yuhe Zhang, Haiyang Yong, Zhili Li, Sigen A, Xiaobei Huang and Dezhong Zhou

Chem. Mater., 2023, 35, 6573
DOI: 10.1021/acs.chemmater.3c01151

A review of green techniques for the synthesis of size-controlled starch-based nanoparticles and their applications as nanodelivery systems

Chao Qiu, Yao Hu, Zhengyu Jin, David Julian McClements, Yang Qin, Xueming Xu and Jinpeng Wang

Trends in Food Science & Technology, 2019, 92, 138
DOI: 10.1016/j.tifs.2019.08.007

Redox-Sensitive Hydroxyethyl Starch–Doxorubicin Conjugate for Tumor Targeted Drug Delivery

Hang Hu, Yihui Li, Qing Zhou, Yanxiao Ao, Chan Yu, Ying Wan, Huibi Xu, Zifu Li and Xiangliang Yang

ACS Appl. Mater. Interfaces, 2016, 8, 30833
DOI: 10.1021/acsami.6b11932

Combining targeted chemotherapy of hydroxyethyl starch prodrug and photothermal therapy of MoS2 for treatment of bladder cancer

Kaidong Zhao and Min Lin

Colloid Polym Sci, 2023, 301, 371
DOI: 10.1007/s00396-023-05065-6

Injectable NIR-II-responsive nanocomposite hydrogels containing gold nanoparticle-decorated carbon nanotubes for controllable drug delivery and tumor therapy

Yi-Jhen Lai, Po-Ju Ting, Shu-Jyuan Yang, Grace Chen, Chieh-Ming Tsai, Chih-Hao Chang and Yi-Cheun Yeh

Acta Biomaterialia, 2026, 209, 225
DOI: 10.1016/j.actbio.2025.11.050

Acid-sensitive dextran prodrug: A higher molecular weight makes a better efficacy

Di Li, Jiandong Han, Jianxun Ding, Li Chen and Xuesi Chen

Carbohydrate Polymers, 2017, 161, 33
DOI: 10.1016/j.carbpol.2016.12.070

In vivo computation with sensor fusion and search acceleration for smart tumor homing

Muhammad Ali, Yifan Chen, Michael J. Cree and Mengjie Zhang

Computers in Biology and Medicine, 2022, 148, 105887
DOI: 10.1016/j.compbiomed.2022.105887

Preparation of an injectable doxorubicin surface modified cellulose nanofiber gel and evaluation of its anti‐tumor and anti‐metastasis activity in melanoma

Najmeh Alizadeh, Vajihe Akbari, Maryam Nurani and Azade Taheri

Biotechnology Progress, 2018, 34, 537
DOI: 10.1002/btpr.2598

Versatile functionalization of pectic conjugate: From design to biomedical applications

Jie Chen, Ming-Shun Mei, Yongbin Xu, Songshan Shi, Shunchun Wang and Huijun Wang

Carbohydrate Polymers, 2023, 306, 120605
DOI: 10.1016/j.carbpol.2023.120605

Enhancing Doxorubicin Delivery toward Tumor by Hydroxyethyl Starch-g-Polylactide Partner Nanocarriers

Chan Yu, Qing Zhou, Fan Xiao, Yihui Li, Hang Hu, Ying Wan, Zifu Li and Xiangliang Yang

ACS Appl. Mater. Interfaces, 2017, 9, 10481
DOI: 10.1021/acsami.7b00048

Microwave-assisted extraction, structural elucidation, and in vitro anti-glioma and immunostimulatory activity of polysaccharide from Panax ginseng C. A. Meyer

Dongxue Cao, Enwei Wei, Zeyu Wang, Zhengyu Hu, Ling Qi, Hongli Zhou and Jingli Zhao

Industrial Crops and Products, 2022, 189, 115729
DOI: 10.1016/j.indcrop.2022.115729

The assembly and antitumor activity of lycium barbarum polysaccharide-platinum-based conjugates

Ying Wang, Qianqian Han, Feng Bai, Qiang Luo, Mingliang Wu, Gang Song, Hongmei Zhang and Yanqing Wang

Journal of Inorganic Biochemistry, 2020, 205, 111001
DOI: 10.1016/j.jinorgbio.2020.111001

Doxorubicin-Bound Hydroxyethyl Starch Conjugate Nanoparticles with pH/Redox Responsive Linkage for Enhancing Antitumor Therapy

Ronghua Tan, Danlei Tian, Jiaoyan Liu, Congcong Wang and Ying Wan

IJN, 2021, Volume 16, 4527
DOI: 10.2147/IJN.S314705

Hydroxyethyl Starch-Based Nanoparticles Featured with Redox-Sensitivity and Chemo-Photothermal Therapy for Synergized Tumor Eradication

Chan Yu, Chuqi Liu, Shaocong Wang, Zheng Li, Hang Hu, Ying Wan and Xiangliang Yang

Cancers, 2019, 11, 207
DOI: 10.3390/cancers11020207

Effect of Radix Hedysari Polysaccharide on Glioma by Cell Cycle Arrest and TNF-α Signaling Pathway Regulation

Xiaolong Du, Yujing Zhao, Yongqian Ma, Hongshun Xing and Xingang Li

International Journal of Polymer Science, 2019, 2019, 1
DOI: 10.1155/2019/2725084

Semi-Autonomous In Vivo Computation in Internet of Bio-Nano Things

Muhammad Ali, Yifan Chen and Michael J. Cree

IEEE Internet Things J., 2023, 10, 16845
DOI: 10.1109/JIOT.2023.3272213