Longji Dai, Gufeng Yin, Zekun Tuo, Zhichao Chang, Xinye Xia, Zhongjin Zuo, Yongchun Hu, Shuangshuang Li, Shugen Kuang, Yunfei Lai, Tzumei Wang, Chao Wang, Chong Qin, Xinyao Li and Wang Zhou

Nat. Chem., 2026
DOI: 10.1038/s41557-026-02167-w

Highly Enantioselective Rhodium‐Catalyzed Addition of Arylboroxines to Simple Aryl Ketones: Efficient Synthesis of Escitalopram

Linwei Huang, Jinbin Zhu, Guangjun Jiao, Zheng Wang, Xingxin Yu, Wei‐Ping Deng and Wenjun Tang

Angewandte Chemie, 2016, 128, 4603
DOI: 10.1002/ange.201600979

Synthesis of Axially Chiral Phenanthryl–Aryl Phosphines via Nickel‐Catalyzed Atroposelective [4 + 2] Cycloaddition with Broad Ligand Applications

Jia‐Hao Zhao, Zhen‐Dong Guo, Ting Qi, Qiu‐Xia Lu, Shufeng Chen, Jian Wang, Mei‐Lin Feng, Chao Sun and Jialin Ming

Angew Chem Int Ed, 2026, 65
DOI: 10.1002/anie.202519122

Hydroxorhodium/Chiral Diene Complexes as Effective Catalysts for the Asymmetric Arylation of 3‐Aryl‐3‐hydroxyisoindolin‐1‐ones

Takahiro Nishimura, Akira Noishiki, Yusuke Ebe and Tamio Hayashi

Angew Chem Int Ed, 2013, 52, 1777
DOI: 10.1002/anie.201208593

A chiral Rh–phosphite complex displaying high activity in the enantioselective Rh-catalyzed addition of arylboronic acids to carbonyl compounds: when and why atropos is better than tropos

Varsha R. Jumde, Sarah Facchetti and Anna Iuliano

Tetrahedron: Asymmetry, 2010, 21, 2775
DOI: 10.1016/j.tetasy.2010.11.009

α,β-Divinyl Tetrahydropyrroles as Chiral Chain Diene Ligands in Rhodium(I)-Catalyzed Enantioselective Conjugated Additions

Qian Li, Zhe Dong and Zhi-Xiang Yu

Org. Lett., 2011, 13, 1122
DOI: 10.1021/ol103152t

Rhodium-catalyzed arylation of acylsilanes with sodium tetraarylborates

Takanori Matsuda, Kohei Mizuno and Shoichi Watanuki

Journal of Organometallic Chemistry, 2014, 765, 64
DOI: 10.1016/j.jorganchem.2014.05.005

Base‐Free Conditions for Rhodium‐Catalyzed Asymmetric Arylation To Produce Stereochemically Labile α‐Aryl Ketones

Xiaowei Dou, Yixin Lu and Tamio Hayashi

Angewandte Chemie, 2016, 128, 6851
DOI: 10.1002/ange.201601709

Enantio‐ and Z‐Selective δ‐Hydroarylation of Aryl‐Substituted 1,3‐Dienes via Rh‐Catalyzed Conjugate Addition

Hima Kozhummal, Sandip Kumar Das, Christopher J. C. Cooze and Rylan J. Lundgren

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202406102

Vicinal-Diamine-Based Chiral Chain Dienes as Ligands for Rhodium(I)-Catalyzed Highly Enantioselective Conjugated Additions

Yazhou Wang, Xichao Hu and Haifeng Du

Org. Lett., 2010, 12, 5482
DOI: 10.1021/ol1023536

Enantioselective Rh(I)-Catalyzed Cyclization of Arylboron Compounds onto Ketones

Darryl W. Low, Graham Pattison, Martin D. Wieczysty, Gwydion H. Churchill and Hon Wai Lam

Org. Lett., 2012, 14, 2548
DOI: 10.1021/ol300845q

Enhancement of the Catalytic Activity of Chiral H8‐BINOL Titanium Complexes by Introduction of Sterically Demanding Groups at the 3‐Position

Yasuki Hayashi, Nobuaki Yamamura, Takahiro Kusukawa and Toshiro Harada

Chemistry A European J, 2016, 22, 12095
DOI: 10.1002/chem.201601854

Rhodium/chiral diene-catalyzed asymmetric methylation of N-sulfonylarylimines with trimethylboroxine

Takahiro Nishimura, Akram Ashouri, Yusuke Ebe, Yuko Maeda and Tamio Hayashi

Tetrahedron: Asymmetry, 2012, 23, 655
DOI: 10.1016/j.tetasy.2012.04.021

Highly Enantioselective Synthesis of Monofluoroalkenes by Rhodium-Catalyzed Asymmetric Arylation/Defluorination of Allyl Difluorides

Yuhang Pan, Xiaosa Lu, Huayu Qiu, Tamio Hayashi and Yinhua Huang

Org. Lett., 2020, 22, 8413
DOI: 10.1021/acs.orglett.0c03044

Synthesis of Dibenzo[a,e]cyclooctatetraenes Enabled by a Palladium-Catalyzed Cross-Coupling Reaction

Yinjie Zhu and Ping Lu

Org. Lett., 2026, 28, 686
DOI: 10.1021/acs.orglett.5c04802

Selective arylation of aldehydes with di-rhodium(II)/NHC catalysts

Alexandre F. Trindade, Vânia André, M. Teresa Duarte, Luís F. Veiros, Pedro M.P. Gois and Carlos A.M. Afonso

Tetrahedron, 2010, 66, 8494
DOI: 10.1016/j.tet.2010.08.050

The rhodium-catalysed 1,2-addition of arylboronic acids to aldehydes and ketones with sulfonated S-Phos

James R. White, Gareth J. Price, Pawel K. Plucinski and Christopher G. Frost

Tetrahedron Letters, 2009, 50, 7365
DOI: 10.1016/j.tetlet.2009.10.082

A General Rhodium‐Catalyzed Cyanation of Aryl and Alkenyl Boronic Acids

Pazhamalai Anbarasan, Helfried Neumann and Matthias Beller

Angew Chem Int Ed, 2011, 50, 519
DOI: 10.1002/anie.201006044

Asymmetric Synthesis of Fluorinated Allenes by Rhodium‐Catalyzed Enantioselective Alkylation/Defluorination of Propargyl Difluorides with Alkylzincs

Jia Sheng Ng and Tamio Hayashi

Angew Chem Int Ed, 2021, 60, 20771
DOI: 10.1002/anie.202109290

Chiral Diene Ligands in Asymmetric Catalysis

Yinhua Huang and Tamio Hayashi

Chem. Rev., 2022, 122, 14346
DOI: 10.1021/acs.chemrev.2c00218

Axially chiral C2-symmetric N-heterocyclic carbene (NHC) palladium complexes-catalyzed asymmetric arylation of aldehydes with arylboronic acids

Rui Zhang, Qin Xu, Xiuchun Zhang, Tao Zhang and Min Shi

Tetrahedron: Asymmetry, 2010, 21, 1928
DOI: 10.1016/j.tetasy.2010.06.041

Synthesis of Planar Chiral [2.2]Paracyclophanyl Imidazo[1,5-a]pyridinium Salts for the Rhodium-Catalyzed Asymmetric Arylation

Dengxia Wang, Yudao Ma, Fuyan He, Wenzeng Duan, Lei Zhao and Chun Song

Synthetic Communications, 2013, 43, 810
DOI: 10.1080/00397911.2011.610548

Hydroxoiridium/Chiral Diene Complexes as Effective Catalysts for Asymmetric Annulation of α‐Oxo‐ and Iminocarboxamides with 1,3‐Dienes

Miyuki Hatano and Takahiro Nishimura

Angewandte Chemie, 2015, 127, 11099
DOI: 10.1002/ange.201505382

Chiral Tetrafluorobenzobarrelene Ligands for the Rhodium‐Catalyzed Asymmetric Cycloisomerization of Oxygen‐ and Nitrogen‐Bridged 1,6‐Enynes

Takahiro Nishimura, Takahiro Kawamoto, Makoto Nagaosa, Hana Kumamoto and Tamio Hayashi

Angew Chem Int Ed, 2010, 49, 1638
DOI: 10.1002/anie.200906792

Asymmetric Cyclopropanation of Alkenes with Dimethyl Diazomalonate Catalyzed by Chiral Diene–Rhodium Complexes

Takahiro Nishimura, Yuko Maeda and Tamio Hayashi

Angewandte Chemie, 2010, 122, 7482
DOI: 10.1002/ange.201003775

Effect of Chiral Diene Ligands in Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to α,β-Unsaturated Sulfonyl Compounds

Takahiro Nishimura, Yuka Takiguchi and Tamio Hayashi

J. Am. Chem. Soc., 2012, 134, 9086
DOI: 10.1021/ja303109q

Rhodium-Catalyzed Asymmetric Arylation/Defluorination of 1-(Trifluoromethyl)alkenes Forming Enantioenriched 1,1-Difluoroalkenes

Yinhua Huang and Tamio Hayashi

J. Am. Chem. Soc., 2016, 138, 12340
DOI: 10.1021/jacs.6b07844

Asymmetric Synthesis of (Triaryl)methylamines by Rhodium-Catalyzed Addition of Arylboroxines to Cyclic N-Sulfonyl Ketimines

Takahiro Nishimura, Akira Noishiki, Gavin Chit Tsui and Tamio Hayashi

J. Am. Chem. Soc., 2012, 134, 5056
DOI: 10.1021/ja300697c

Synthesis of Rhodium Complexes with Chiral Diene Ligands via Diastereoselective Coordination and Their Application in the Asymmetric Insertion of Diazo Compounds into E−H Bonds

Nikita M. Ankudinov, Denis A. Chusov, Yulia V. Nelyubina and Dmitry S. Perekalin

Angew Chem Int Ed, 2021, 60, 18712
DOI: 10.1002/anie.202105179

Catalytic Enantioselective Synthesis of Diarylmethanols from Aryl Bromides and Aldehydes by Using Organolithium Reagents

Yuya Nakagawa, Yusuke Muramatsu and Toshiro Harada

Eur J Org Chem, 2010, 2010, 6535
DOI: 10.1002/ejoc.201001254

Iridium/Chiral Diene‐Catalyzed Enantioselective (3+2) Annulation of Aromatic Ketimines with 1,3‐Enynes via C−H Activation

Midori Nagamoto, Kana Sakamoto and Takahiro Nishimura

Adv Synth Catal, 2018, 360, 791
DOI: 10.1002/adsc.201701378

Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to β-Phthaliminoacrylate Esters toward the Synthesis of β-Amino Acids

Takahiro Nishimura, Jun Wang, Makoto Nagaosa, Kazuhiro Okamoto, Ryo Shintani, Fuk-yee Kwong, Wing-yiu Yu, Albert S. C. Chan and Tamio Hayashi

J. Am. Chem. Soc., 2010, 132, 464
DOI: 10.1021/ja909642h

A General Rhodium‐Catalyzed Cyanation of Aryl and Alkenyl Boronic Acids

Pazhamalai Anbarasan, Helfried Neumann and Matthias Beller

Angewandte Chemie, 2011, 123, 539
DOI: 10.1002/ange.201006044

Chiral Lithium Amido Aryl Zincates: Simple and Efficient Chemo‐ and Enantio‐Selective Aryl Transfer Reagents

Pauline Chaumont‐Olive, Mathieu Rouen, Gabriella Barozzino‐Consiglio, Amel Ben Abdeladhim, Jacques Maddaluno and Anne Harrison‐Marchand

Angewandte Chemie, 2019, 131, 3225
DOI: 10.1002/ange.201813510

Highly Enantioselective Synthesis of Chiral Benzhydrols via Manganese Catalyzed Asymmetric Hydrogenation of Unsymmetrical Benzophenones Using an Imidazole-Based Chiral PNN Tridentate Ligand

Fei Ling, Huacui Hou, Jiachen Chen, Sanfei Nian, Xiao Yi, Ze Wang, Dingguo Song and Weihui Zhong

Org. Lett., 2019, 21, 3937
DOI: 10.1021/acs.orglett.9b01056

Rhodium‐Catalyzed Asymmetric Cycloisomerization of 1,6‐Ene‐ynamides

Takahiro Nishimura, Yuka Takiguchi, Yuko Maeda and Tamio Hayashi

Adv Synth Catal, 2013, 355, 1374
DOI: 10.1002/adsc.201300148

Structural study of analogues of Wilkinson’s compound [Rh(X)(PPh3)3] (X = NCO, NCS, N3, N(CN)2) and derivatives [Rh(NCO)(O2)(PPh3)3] and [Rh(η6-C6H5B(NCO)Ph2)(PPh3)2]

Manuel A. Fernandes, Gcinaphi Z. Mashabane, Rosemarie Weber and Laurence Carlton

Polyhedron, 2020, 181, 114468
DOI: 10.1016/j.poly.2020.114468

Synthesis of new alkoxy/sulfonate-substituted carbene precursors derived from [2.2]paracyclophane and their application in the asymmetric arylation of aldehydes

Wenzeng Duan, Yudao Ma, Bo Qu, Lei Zhao, Jianqiang Chen and Chun Song

Tetrahedron: Asymmetry, 2012, 23, 1369
DOI: 10.1016/j.tetasy.2012.09.001

A Chiral Nitrogen Ligand for Enantioselective, Iridium‐Catalyzed Silylation of Aromatic C−H Bonds

Bo Su, Tai‐Gang Zhou, Xian‐Wei Li, Xiao‐Ru Shao, Pei‐Lin Xu, Wen‐Lian Wu, John F. Hartwig and Zhang‐Jie Shi

Angew Chem Int Ed, 2017, 56, 1092
DOI: 10.1002/anie.201609939

Rhodium-Catalyzed Asymmetric Arylation of Azomethine Imines

Ryo Shintani, Ying-Teck Soh and Tamio Hayashi

Org. Lett., 2010, 12, 4106
DOI: 10.1021/ol101700v

Intramolecular Benzyne–Phenolate [4+2] Cycloadditions

Hiroshi Takikawa, Arata Nishii, Hiromu Takiguchi, Hirotoshi Yagishita, Masato Tanaka, Keiichi Hirano, Masanobu Uchiyama, Ken Ohmori and Keisuke Suzuki

Angew Chem Int Ed, 2020, 59, 12440
DOI: 10.1002/anie.202003131

Rhodium/Chiral Diene-Catalyzed Asymmetric Cyclopolymerization of Achiral 1,8-Diynes

Yoshitaka Ichikawa, Takahiro Nishimura and Tamio Hayashi

Organometallics, 2011, 30, 2342
DOI: 10.1021/om200088q

Stereoselective and Atom-Economic Alkenyl C–H Allylation/Alkenylation in Aqueous Media by Iridium Catalysis

Yinhua Huang, Liangyao Xu, Feifei Yu, Wenzhou Shen, Xiunan Lu, Liyuan Ding, Liangjun Zhong, Guofu Zhong and Jian Zhang

J. Org. Chem., 2020, 85, 7225
DOI: 10.1021/acs.joc.0c00619

Diastereo-, Enantio-, and Z-Selective α,δ-Difunctionalization of Electron-Deficient Dienes Initiated by Rh-Catalyzed Conjugate Addition

Christopher J. C. Cooze, Wesley McNutt, Markus D. Schoetz, Bohdan Sosunovych, Svetlana Grigoryan and Rylan J. Lundgren

J. Am. Chem. Soc., 2021, 143, 10770
DOI: 10.1021/jacs.1c05427

Asymmetric Conjugate Alkynylation of Cyclic α,β‐Unsaturated Carbonyl Compounds with a Chiral Diene Rhodium Catalyst

Xiaowei Dou, Yinhua Huang and Tamio Hayashi

Angew Chem Int Ed, 2016, 55, 1133
DOI: 10.1002/anie.201509778

Asymmetric Hydrophosphination of Heterobicyclic Alkenes: Facile Access to Phosphine Ligands for Asymmetric Catalysis

Zhiwu Lu, Haoyang Zhang, Zhiping Yang, Ning Ding, Ling Meng and Jun Wang

ACS Catal., 2019, 9, 1457
DOI: 10.1021/acscatal.8b04787

Base‐Free Conditions for Rhodium‐Catalyzed Asymmetric Arylation To Produce Stereochemically Labile α‐Aryl Ketones

Xiaowei Dou, Yixin Lu and Tamio Hayashi

Angew Chem Int Ed, 2016, 55, 6739
DOI: 10.1002/anie.201601709

Crystal Structure Studies towards the Synthesis and Applications of N-heterocyclic Carbene–Metal Complexes Derived from [2.2]Paracyclophane

Wenzeng Duan, Yudao Ma, Yanmin Huo and Qingxia Yao

Australian Journal of Chemistry, 2015, 68, 1472
DOI: 10.1071/CH15002

Asymmetric Synthesis of Triarylmethanes by Rhodium-Catalyzed Enantioselective Arylation of Diarylmethylamines with Arylboroxines

Yinhua Huang and Tamio Hayashi

J. Am. Chem. Soc., 2015, 137, 7556
DOI: 10.1021/jacs.5b03277

Bu4N+ Alkoxide-Initiated/Autocatalytic Addition Reactions with Organotrimethylsilanes

Manas Das and Donal F. O’Shea

J. Org. Chem., 2014, 79, 5595
DOI: 10.1021/jo5007637

Chiral Tetrafluorobenzobarrelene Ligands for the Rhodium‐Catalyzed Asymmetric Cycloisomerization of Oxygen‐ and Nitrogen‐Bridged 1,6‐Enynes

Takahiro Nishimura, Takahiro Kawamoto, Makoto Nagaosa, Hana Kumamoto and Tamio Hayashi

Angewandte Chemie, 2010, 122, 1682
DOI: 10.1002/ange.200906792

Ligand-Controlled Rhodium-Catalyzed Site-Selective Asymmetric Addition of Arylboronic Acids to α,β-Unsaturated Cyclic N-Sulfonyl Ketimines

Chun-Yan Wu, Yu-Fang Zhang and Ming-Hua Xu

Org. Lett., 2018, 20, 1789
DOI: 10.1021/acs.orglett.8b00289

Rhodium-Catalyzed Asymmetric Arylation

Ping Tian, Han-Qing Dong and Guo-Qiang Lin

ACS Catal., 2012, 2, 95
DOI: 10.1021/cs200562n

Rhodium(I)‐Catalyzed 1,4‐Silicon Shift of Unactivated Silanes from Aryl to Alkyl: Enantioselective Synthesis of Indanol Derivatives

Tobias Seiser and Nicolai Cramer

Angewandte Chemie, 2010, 122, 10361
DOI: 10.1002/ange.201005399

Fast Enantio‐ and Chemoselective Arylation of Ketones with Organoboronic Esters Enabled by Nickel/N‐Heterocyclic Carbene Catalysis

Yuan Cai, Lin‐Xin Ruan, Abdul Rahman and Shi‐Liang Shi

Angewandte Chemie, 2021, 133, 5322
DOI: 10.1002/ange.202015021

Novel Axially Chiral Phosphine Ligand with a Fluoro Alcohol Moiety for Rh-Catalyzed Asymmetric Arylation of Aromatic Aldehydes

Satoshi Morikawa, Kyosuke Michigami and Hideki Amii

Org. Lett., 2010, 12, 2520
DOI: 10.1021/ol100697a

A Chiral Nitrogen Ligand for Enantioselective, Iridium‐Catalyzed Silylation of Aromatic C−H Bonds

Bo Su, Tai‐Gang Zhou, Xian‐Wei Li, Xiao‐Ru Shao, Pei‐Lin Xu, Wen‐Lian Wu, John F. Hartwig and Zhang‐Jie Shi

Angewandte Chemie, 2017, 129, 1112
DOI: 10.1002/ange.201609939

Regularized regression analysis of digitized molecular structures in organic reactions for quantification of steric effects

Shigeru Yamaguchi, Takahiro Nishimura, Yuta Hibe, Masaki Nagai, Hirofumi Sato and Ian Johnston

J. Comput. Chem., 2017, 38, 1825
DOI: 10.1002/jcc.24791

Single-Step Construction of Planar and Central Chirality in Metallocenes by Rhodium-Catalyzed Desymmetric Cyclization

Ying Yang, Nan-Nan Hang, Hui-Yao Liu, Shufeng Chen and Jialin Ming

ACS Catal., 2023, 13, 12464
DOI: 10.1021/acscatal.3c03037

Iridium‐Catalyzed Hydroarylation via C−H Bond Activation

Takahiro Nishimura

The Chemical Record, 2021, 21, 3532
DOI: 10.1002/tcr.202100109

Chiral Sulfoxide‐Olefin Ligands: Completely Switchable Stereoselectivity in Rhodium‐Catalyzed Asymmetric Conjugate Additions

Guihua Chen, Jiangyang Gui, Liangchun Li and Jian Liao

Angewandte Chemie, 2011, 123, 7823
DOI: 10.1002/ange.201102586

Combining Enantioselective Rh‐Catalyzed Conjugate Addition and Ir‐Catalyzed Allylic Alkylation in Stereodivergent, Multicomponent Coupling Reactions to Form Three Stereocenters**

Qiqige Qiqige, Rylan J. Lundgren and Duanyang Kong

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202300727

Asymmetric conjugate addition of cis-2-arylethenylboronic acids catalyzed by chiral diene/rhodium complexes: 1,4-rhodium shift from alkenylrhodium to arylrhodium intermediates

Keigo Sasaki and Tamio Hayashi

Tetrahedron: Asymmetry, 2012, 23, 373
DOI: 10.1016/j.tetasy.2012.03.004

Highly Enantioselective Rhodium‐Catalyzed Addition of Arylboroxines to Simple Aryl Ketones: Efficient Synthesis of Escitalopram

Linwei Huang, Jinbin Zhu, Guangjun Jiao, Zheng Wang, Xingxin Yu, Wei‐Ping Deng and Wenjun Tang

Angew Chem Int Ed, 2016, 55, 4527
DOI: 10.1002/anie.201600979

A simple rhodium-catalyzed addition reaction of aldehydes with arylboronic acids in aqueous γ-valerolactone

Min-xiao Xu, Kai-ming Zhang and Jie Zhang

Mendeleev Communications, 2022, 32, 397
DOI: 10.1016/j.mencom.2022.05.036

Practical Enantioselective Arylation and Heteroarylation of Aldehydes with In Situ Prepared Organotitanium Reagents Catalyzed by 3‐Aryl‐H8‐BINOL‐Derived Titanium Complexes

Ami Uenishi, Yuya Nakagawa, Hironobu Osumi and Toshiro Harada

Chemistry A European J, 2013, 19, 4896
DOI: 10.1002/chem.201203946

Synthesis of catalytically active diene and cyclopentadienyl rhodium halide complexes

Andrey V. Kolos and Dmitry S. Perekalin

Mendeleev Communications, 2021, 31, 1
DOI: 10.1016/j.mencom.2021.01.001

Synthesis of new benzimidazolium salts and their application in the asymmetric arylation of aldehydes

Wei-Ping He, Bi-Hui Zhou, Ya-Li Zhou, Xiang-Rong Li, Li-Mei Fan, Hao-Wen Shou and Jie Li

Tetrahedron Letters, 2016, 57, 3152
DOI: 10.1016/j.tetlet.2016.06.023

Critical view on the recent enantioselective synthesis of alcohols, amines and related molecules having tertiary benzylic stereocenter

Sankalan Mondal, Deblina Roy and Gautam Panda

Tetrahedron, 2018, 74, 4619
DOI: 10.1016/j.tet.2018.07.011

Development of Catalytic Asymmetric Reactions Based on Conformational Control

Kazuhiro Kondo

J. Synth. Org. Chem. Jpn., 2014, 72, 405
DOI: 10.5059/yukigoseikyokaishi.72.405

Enantioselective Rhodium‐Catalyzed Addition of Arylboronic Acids to Trifluoromethyl Ketones

Renshi Luo, Ke Li, Yuling Hu and Wenjun Tang

Adv Synth Catal, 2013, 355, 1297
DOI: 10.1002/adsc.201201125

Rhodium(I)‐Catalyzed 1,4‐Silicon Shift of Unactivated Silanes from Aryl to Alkyl: Enantioselective Synthesis of Indanol Derivatives

Tobias Seiser and Nicolai Cramer

Angew Chem Int Ed, 2010, 49, 10163
DOI: 10.1002/anie.201005399

Asymmetric Transformations under Iridium/Chiral Diene Catalysis

Midori Nagamoto and Takahiro Nishimura

ACS Catal., 2017, 7, 833
DOI: 10.1021/acscatal.6b02495

An Unexpected Michael–Aldol–Smiles Rearrangement Sequence for the Synthesis of Versatile Optically Active Bicyclic Structures by Using Asymmetric Organocatalysis

Nicole Holub, Hao Jiang, Marcio W. Paixão, Caterina Tiberi and Karl A. Jørgensen

Chemistry A European J, 2010, 16, 4337
DOI: 10.1002/chem.200903274

Asymmetric Cyclopropanation of Alkenes with Dimethyl Diazomalonate Catalyzed by Chiral Diene–Rhodium Complexes

Takahiro Nishimura, Yuko Maeda and Tamio Hayashi

Angew Chem Int Ed, 2010, 49, 7324
DOI: 10.1002/anie.201003775

Asymmetric 2,3-Addition of Sulfinylamines with Arylboronic Acids Enabled by Nickel Catalysis

Longlong Xi, Xiaowu Fang, Minyan Wang and Zhuangzhi Shi

J. Am. Chem. Soc., 2024, 146, 17587
DOI: 10.1021/jacs.4c04050

Nickel‐Catalyzed Intermolecular Asymmetric Addition of Aryl Iodides across Aldehydes

Ziqi Zhu, Jieshuai Xiao, Mingjie Li and Zhuangzhi Shi

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202201370

Rhodium-Catalyzed Asymmetric Arylation of N-Tosyl Ketimines

Ryo Shintani, Momotaro Takeda, Takaoki Tsuji and Tamio Hayashi

J. Am. Chem. Soc., 2010, 132, 13168
DOI: 10.1021/ja106114q

Intramolecular Benzyne–Phenolate [4+2] Cycloadditions

Hiroshi Takikawa, Arata Nishii, Hiromu Takiguchi, Hirotoshi Yagishita, Masato Tanaka, Keiichi Hirano, Masanobu Uchiyama, Ken Ohmori and Keisuke Suzuki

Angewandte Chemie, 2020, 132, 12540
DOI: 10.1002/ange.202003131

Rhodium‐Catalyzed Asymmetric Synthesis of Spirocarbocycles: Arylboron Reagents as Surrogates of 1,2‐Dimetalloarenes

Ryo Shintani, Shingo Isobe, Momotaro Takeda and Tamio Hayashi

Angewandte Chemie, 2010, 122, 3883
DOI: 10.1002/ange.201000937

Aryl Bromides as Inexpensive Starting Materials in the Catalytic Enantioselective Arylation of Aryl Aldehydes: The Additive TMEDA Enhances the Enantioselectivity

Yong-Xin Yang, Yue Liu, Lei Zhang, Yan-E Jia, Pei Wang, Fang-Fang Zhuo, Xian-Tao An and Chao-Shan Da

J. Org. Chem., 2014, 79, 10696
DOI: 10.1021/jo502070r

Development of Highly Active Chiral Titanium Catalysts for the Enantioselective Addition of Various Organometallic Reagents to Aldehydes

Toshiro Harada

The Chemical Record, 2016, 16, 1256
DOI: 10.1002/tcr.201500269

Chiral Sulfoxide‐Olefin Ligands: Completely Switchable Stereoselectivity in Rhodium‐Catalyzed Asymmetric Conjugate Additions

Guihua Chen, Jiangyang Gui, Liangchun Li and Jian Liao

Angew Chem Int Ed, 2011, 50, 7681
DOI: 10.1002/anie.201102586

Planar Chiral Rhodium Complexes of 1,4‐Benzoquinones

Nikita M. Ankudinov, Yulia V. Nelyubina and Dmitry S. Perekalin

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202200195

Iridium/Chiral Diene-Catalyzed Asymmetric 1,6-Addition of Arylboroxines to α,β,γ,δ-Unsaturated Carbonyl Compounds

Takahiro Nishimura, Yuichi Yasuhara, Takahiro Sawano and Tamio Hayashi

J. Am. Chem. Soc., 2010, 132, 7872
DOI: 10.1021/ja1034842

Enantioselective C–C and C–heteroatom bond forming reactions using chiral ferrocene catalysts

Michal Drusan and Radovan Šebesta

Tetrahedron, 2014, 70, 759
DOI: 10.1016/j.tet.2013.11.012

Easily accessible chiral dicyclopentadiene ligands for rhodium-catalyzed enantioselective 1,4-addition reactions

Cheng Shao, Hong-Jie Yu, Chen-Guo Feng, Rui Wang and Guo-Qiang Lin

Tetrahedron Letters, 2012, 53, 2733
DOI: 10.1016/j.tetlet.2012.03.087

Asymmetric Conjugate Alkynylation of Cyclic α,β‐Unsaturated Carbonyl Compounds with a Chiral Diene Rhodium Catalyst

Xiaowei Dou, Yinhua Huang and Tamio Hayashi

Angewandte Chemie, 2016, 128, 1145
DOI: 10.1002/ange.201509778

Racemic NHC–Iridium Complexes with Electron-Poor Diene Ligands and Their Reactivity in the Intramolecular Hydroamination Reaction

Pengchao Gao, Daven Foster, Gellért Sipos, Brian W. Skelton, Alexandre N. Sobolev, Stephen A. Moggach and Reto Dorta

Organometallics, 2019, 38, 3568
DOI: 10.1021/acs.organomet.9b00414

Rhodium-Catalyzed Asymmetric Arylation of Allyl Sulfones under the Conditions of Isomerization into Alkenyl Sulfones

Kelvin Meng-Hui Lim and Tamio Hayashi

J. Am. Chem. Soc., 2015, 137, 3201
DOI: 10.1021/jacs.5b00216

Fast Enantio‐ and Chemoselective Arylation of Ketones with Organoboronic Esters Enabled by Nickel/N‐Heterocyclic Carbene Catalysis

Yuan Cai, Lin‐Xin Ruan, Abdul Rahman and Shi‐Liang Shi

Angew Chem Int Ed, 2021, 60, 5262
DOI: 10.1002/anie.202015021

Enantio‐ and Z‐Selective δ‐Hydroarylation of Aryl‐Substituted 1,3‐Dienes via Rh‐Catalyzed Conjugate Addition

Hima Kozhummal, Sandip Kumar Das, Christopher J. C. Cooze and Rylan J. Lundgren

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202406102

Rhodium(I)-N-Heterocyclic Carbene-Catalyzed Addition of Sodium Tetraphenylborate to Ketones to Form Tertiary Alcohols

Murat Yiğit, Beyhan Yiğit and İsmail Özdemir

HETEROCYCLES, 2014, 89, 2562
DOI: 10.3987/COM-14-13092

Ru-Catalyzed Asymmetric Addition of Arylboronic Acids to Aliphatic Aldehydes via P-Chiral Monophosphorous Ligands

Rui Miao, Yanping Xia, Yifei Wei, Lu Ouyang and Renshi Luo

Molecules, 2022, 27, 3898
DOI: 10.3390/molecules27123898

Nickel‐Catalyzed Asymmetric Propargyl‐Aryl Cross‐Electrophile Coupling

Linlin Ding, Yue Zhao, Hongjian Lu, Zhuangzhi Shi and Minyan Wang

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202313655

Iridium-Catalyzed Asymmetric Reactions Realizing High Atom Efficiency

Midori Nagamoto, Yusuke Ebe and Takahiro Nishimura

J. Syn. Org. Chem., Jpn., 2017, 75, 421
DOI: 10.5059/yukigoseikyokaishi.75.421

Rhodium-Catalyzed Asymmetric Addition to 4- or 5-Carbonyl-cycloenones through Dynamic Kinetic Resolution: Enantioselective Synthesis of (−)-Cannabidiol

Wen-Cong Li, He Meng, Jialin Ming and Shufeng Chen

Org. Lett., 2024, 26, 1364
DOI: 10.1021/acs.orglett.3c04281

Asymmetric Alkylation of N-Sulfonylbenzamides with Vinyl Ethers via C–H Bond Activation Catalyzed by Hydroxoiridium/Chiral Diene Complexes

Miyuki Hatano, Yusuke Ebe, Takahiro Nishimura and Hideki Yorimitsu

J. Am. Chem. Soc., 2016, 138, 4010
DOI: 10.1021/jacs.6b01591

Aryloxymethyltrifluoroborates for Rhodium-Catalyzed Asymmetric Conjugate Arylation. o-Methoxyarylation through 1,4-Rhodium Shift

Jialin Ming and Tamio Hayashi

Org. Lett., 2016, 18, 6452
DOI: 10.1021/acs.orglett.6b03347

Convergent Synthesis of Fluorene Derivatives by a Rhodium‐Catalyzed Stitching Reaction/Alkene Isomerization Sequence

Masaki Nishida and Ryo Shintani

Chemistry A European J, 2019, 25, 7475
DOI: 10.1002/chem.201901519

Asymmetric Synthesis of Chiral Bicyclo[2.2.1]hepta-2,5-diene Ligands through Rhodium-Catalyzed Asymmetric Arylative Bis-cyclization of a 1,6-Enyne

Chao Sun, He Meng, Chen Chen, Haili Wei, Jialin Ming and Tamio Hayashi

Org. Lett., 2021, 23, 6311
DOI: 10.1021/acs.orglett.1c02088

Rhodium-Catalyzed Asymmetric Annulation of Unactivated Alkynes with 3-(ortho-Boronated Aryl) Conjugated Enones: Enantioselective Synthesis of 2,3-Disubstituted Indenes

Yu Sun, Jiayu Pan, Xiuqi Wang, Xiaoli Bu, Mengtao Ma and Fei Xue

J. Org. Chem., 2023, 88, 6140
DOI: 10.1021/acs.joc.2c02957

Iridium-Catalyzed Branch-Selective Hydroarylation of Vinyl Ethers via C–H Bond Activation

Yusuke Ebe and Takahiro Nishimura

J. Am. Chem. Soc., 2015, 137, 5899
DOI: 10.1021/jacs.5b03099

Nickel‐Catalyzed Enantioselective Carbonyl Addition of Aryl Chlorides and Bromides to Aldehydes

Mingjie Jiang, Limei Yu, Chenhui Zou, Hao Yuan, Minghui Xu, Bin Chen, Ping Hu, Bi‐Qin Wang and Peng Cao

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202401591

C1-Symmetric Dicyclopentadienes as New Chiral Diene Ligands for Asymmetric Rhodium-Catalyzed Arylation of N-Tosylarylimines

Cheng Shao, Hong-Jie Yu, Nuo-Yi Wu, Chen-Guo Feng and Guo-Qiang Lin

Org. Lett., 2010, 12, 3820
DOI: 10.1021/ol101531r

Enantioselective dialkylzinc-mediated alkynylation, arylation and alkenylation of carbonyl groups

Tomasz Bauer

Coordination Chemistry Reviews, 2015, 299, 83
DOI: 10.1016/j.ccr.2015.03.025

Asymmetric Synthesis of Alkylzincs by Rhodium‐Catalyzed Enantioselective Arylative Cyclization of 1,6‐Enynes with Arylzincs

Jiahua Chen and Tamio Hayashi

Angew Chem Int Ed, 2020, 59, 18510
DOI: 10.1002/anie.202008770

Recent Advances in Catalytic Asymmetric C–C Bond-Forming Reactions to Ketimines Promoted by Metal-Based Catalysts

Naoya Kumagai and Masakatsu Shibasaki

Bulletin of the Chemical Society of Japan, 2015, 88, 503
DOI: 10.1246/bcsj.20140302

Estimating Effective Steric and Electronic Impacts of a Ferrocenyl Group in Organophosphines

Hao Hu, Hiroki Ichiryu, Kiyohiko Nakajima and Masamichi Ogasawara

ACS Omega, 2021, 6, 5981
DOI: 10.1021/acsomega.1c00307

Asymmetric Synthesis of Alkylzincs by Rhodium‐Catalyzed Enantioselective Arylative Cyclization of 1,6‐Enynes with Arylzincs

Jiahua Chen and Tamio Hayashi

Angewandte Chemie, 2020, 132, 18668
DOI: 10.1002/ange.202008770

Nickel‐Catalyzed Intermolecular Asymmetric Addition of Aryl Iodides across Aldehydes

Ziqi Zhu, Jieshuai Xiao, Mingjie Li and Zhuangzhi Shi

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202201370

Hydroxorhodium/Chiral Diene Complexes as Effective Catalysts for the Asymmetric Arylation of 3‐Aryl‐3‐hydroxyisoindolin‐1‐ones

Takahiro Nishimura, Akira Noishiki, Yusuke Ebe and Tamio Hayashi

Angewandte Chemie, 2013, 125, 1821
DOI: 10.1002/ange.201208593

Chiral NHC-Iridium Complexes and Their Performance in Enantioselective Intramolecular Hydroamination and Ring-Opening Amination Reactions

Pengchao Gao, Daven Foster, Gellért Sipos, Brian W. Skelton, Alexandre N. Sobolev and Reto Dorta

Organometallics, 2020, 39, 556
DOI: 10.1021/acs.organomet.9b00770

A Scalable Synthesis of Chiral Himbert Diene Ligands for Asymmetric Catalysis

Raja K. Rit, Hongyi Li, Stephen P. Argent, Katherine M. Wheelhouse, Simon Woodward and Hon Wai Lam

Adv Synth Catal, 2023, 365, 1629
DOI: 10.1002/adsc.202300039

Synthesis of Rhodium Complexes with Chiral Diene Ligands via Diastereoselective Coordination and Their Application in the Asymmetric Insertion of Diazo Compounds into E−H Bonds

Nikita M. Ankudinov, Denis A. Chusov, Yulia V. Nelyubina and Dmitry S. Perekalin

Angewandte Chemie, 2021, 133, 18860
DOI: 10.1002/ange.202105179

Synthesis of novel macrocyclic planar chiral carbene–Ag complexes derived from [2.2]paracyclophane for Rh-catalyzed asymmetric 1,2-additions of arylboronic acids to aromatic aldehydes

Jianqiang Chen, Shaobo Yang, Zhen Chen, Chun Song and Yudao Ma

Tetrahedron: Asymmetry, 2015, 26, 288
DOI: 10.1016/j.tetasy.2015.02.003

Takahiro Nishimura

Angew Chem Int Ed, 2017, 56, 15192
DOI: 10.1002/anie.201707583

Hydroxoiridium/Chiral Diene Complexes as Effective Catalysts for Asymmetric Annulation of α‐Oxo‐ and Iminocarboxamides with 1,3‐Dienes

Miyuki Hatano and Takahiro Nishimura

Angew Chem Int Ed, 2015, 54, 10949
DOI: 10.1002/anie.201505382

Chiral Lithium Amido Aryl Zincates: Simple and Efficient Chemo‐ and Enantio‐Selective Aryl Transfer Reagents

Pauline Chaumont‐Olive, Mathieu Rouen, Gabriella Barozzino‐Consiglio, Amel Ben Abdeladhim, Jacques Maddaluno and Anne Harrison‐Marchand

Angew Chem Int Ed, 2019, 58, 3193
DOI: 10.1002/anie.201813510

Asymmetric Synthesis of Fluorinated Allenes by Rhodium‐Catalyzed Enantioselective Alkylation/Defluorination of Propargyl Difluorides with Alkylzincs

Jia Sheng Ng and Tamio Hayashi

Angewandte Chemie, 2021, 133, 20939
DOI: 10.1002/ange.202109290

Experimental and Theoretical Study on the Role of Monomeric vs Dimeric Rhodium Oxazolidinone Norbornadiene Complexes in Catalytic Asymmetric 1,2- and 1,4-Additions

Manuel Kirchhof, Katrin Gugeler, Felix Richard Fischer, Michal Nowakowski, Alina Bauer, Sonia Alvarez-Barcia, Karina Abitaev, Marc Schnierle, Yaseen Qawasmi, Wolfgang Frey, Angelika Baro, Deven P. Estes, Thomas Sottmann, Mark R. Ringenberg, Bernd Plietker, Matthias Bauer, Johannes Kästner and Sabine Laschat

Organometallics, 2020, 39, 3131
DOI: 10.1021/acs.organomet.0c00310

Nickel‐Catalyzed Asymmetric Propargyl‐Aryl Cross‐Electrophile Coupling

Linlin Ding, Yue Zhao, Hongjian Lu, Zhuangzhi Shi and Minyan Wang

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202313655

ChemInform Abstract: The Concise Synthesis of Chiral Tfb Ligands and Their Application to the Rhodium‐Catalyzed Asymmetric Arylation of Aldehydes.

Takahiro Nishimura, Hana Kumamoto, Makoto Nagaosa and Tamio Hayashi

ChemInform, 2010, 41
DOI: 10.1002/chin.201008022

Iridium-Catalyzed Annulation of Salicylimines with 1,3-Dienes

Yusuke Ebe and Takahiro Nishimura

J. Am. Chem. Soc., 2014, 136, 9284
DOI: 10.1021/ja504990a

Planar-Chiral Phosphine-Olefin Ligands Exploiting a (Cyclopentadienyl)manganese(I) Scaffold To Achieve High Robustness and High Enantioselectivity

Ken Kamikawa, Ya-Yi Tseng, Jia-Hong Jian, Tamotsu Takahashi and Masamichi Ogasawara