Issue 45, 2023

Graphene-based biosensors for detecting coronavirus: a brief review

Abstract

The coronavirus (SARS-CoV-2) disease has affected the globe with 770 437 327 confirmed cases, including about 6 956 900 deaths, according to the World Health Organization (WHO) as of September 2023. Hence, it is imperative to develop diagnostic technologies, such as a rapid cost-effective SARS-CoV-2 detection method. A typical biosensor enables biomolecule detection with an appropriate transducer by generating a measurable signal from the sample. Graphene can be employed as a component for ultrasensitive and selective biosensors based on its physical, optical, and electrochemical properties. Herein, we briefly review graphene-based electrochemical, field-effect transistor (FET), and surface plasmon biosensors for detecting the SARS-CoV-2 target. In addition, details on the surface modification, immobilization, sensitivity and limit of detection (LOD) of all three sensors with regard to SARS-CoV-2 were reported. Finally, the point-of-care (POC) detection of SARS-CoV-2 using a portable smartphone and a wearable watch is a current topic of interest.

Graphical abstract: Graphene-based biosensors for detecting coronavirus: a brief review

Article information

Article type
Minireview
Submitted
11 Sept. 2023
Accepted
24 Okt. 2023
First published
25 Okt. 2023

Nanoscale, 2023,15, 18184-18197

Graphene-based biosensors for detecting coronavirus: a brief review

F. H. Abrha, T. H. Wondimu, M. H. Kahsay, F. Fufa Bakare, D. M. Andoshe and J. Y. Kim, Nanoscale, 2023, 15, 18184 DOI: 10.1039/D3NR04583H

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