Issue 21, 2023

Molecularly imprinted and cladded polymers for constructing a portable plasmonic immunoassay for peptides in biofluids

Abstract

Using two molecularly imprinted and cladded polymers (cMIPs), an inexpensive, fast and portable plasmonic immuno-sandwich assay (PISA) was rationally developed for high-specificity and ultra-sensitive detection of C-peptide in urine. The dual cMIPs-based PISA allowed healthy individuals to be distinguished from diabetes patients and exhibited several significant merits over existing immunoassays, holding great promise in clinical diagnosis.

Graphical abstract: Molecularly imprinted and cladded polymers for constructing a portable plasmonic immunoassay for peptides in biofluids

Supplementary files

Article information

Article type
Communication
Submitted
01 Dec. 2022
Accepted
09 Febr. 2023
First published
10 Febr. 2023

Chem. Commun., 2023,59, 3075-3078

Molecularly imprinted and cladded polymers for constructing a portable plasmonic immunoassay for peptides in biofluids

Z. Guo, Q. Zhang, R. Xing and Z. Liu, Chem. Commun., 2023, 59, 3075 DOI: 10.1039/D2CC06550A

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