Issue 5, 2022

Star-like poly(peptoid)s with selective antibacterial activity

Abstract

We developed new macromolecular engineering approaches enabling the preparation of star-like polypeptoids by ring-opening polymerization. Parallely to the evaluation of their cytotoxicity of the HepG2 human cell line, their screening toward a wide variety of Gram-positive and Gram-negative bacteria higlighted several compounds showing not only good but also selective antimicrobial activity.

Graphical abstract: Star-like poly(peptoid)s with selective antibacterial activity

Supplementary files

Article information

Article type
Paper
Submitted
12 Nov. 2021
Accepted
27 Dec. 2021
First published
03 Janv. 2022

Polym. Chem., 2022,13, 600-612

Star-like poly(peptoid)s with selective antibacterial activity

P. Salas-Ambrosio, A. Tronnet, M. Badreldin, L. Reyes, M. Since, S. Bourgeade-Delmas, B. Dupuy, P. Verhaeghe and C. Bonduelle, Polym. Chem., 2022, 13, 600 DOI: 10.1039/D1PY01529J

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