Issue 5, 2022

Organocatalysis applied to carbohydrates: from roots to current developments

Abstract

Organocatalysis emerged in the last decade as a powerful tool for the synthesis of complex molecules. In the field of carbohydrates, it found widespread use in the synthesis of rare and non-natural carbohydrate derivatives. Additionally, it has also found important application in the stereoselective functionalization of the anomeric carbon in glycosylation reactions. These efforts culminated in the development of different types of catalysts operating through distinct activation modes that allow the selective synthesis of α- or β-glycosides even on daunting substrates. All these advances starting from its first examples in carbohydrate synthesis to the current developments in glycosylation reactions are reviewed.

Graphical abstract: Organocatalysis applied to carbohydrates: from roots to current developments

Article information

Article type
Review Article
Submitted
28 Sept. 2021
Accepted
29 Nov. 2021
First published
30 Nov. 2021

Org. Biomol. Chem., 2022,20, 919-933

Organocatalysis applied to carbohydrates: from roots to current developments

F. Gallier and L. S. D. M. e Miranda, Org. Biomol. Chem., 2022, 20, 919 DOI: 10.1039/D1OB01919H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements