Issue 10, 2020

A self-delivery DNA nanoprobe for reliable microRNA imaging in live cells by aggregation induced red-shift-emission

Abstract

A new DNA nanoprobe based on a Y-shape and pyrene-modified DNA self-assembly is developed to sensitively and specifically detect microRNA through a pyrene excimer–monomer switch. Exhibiting the capability of self-delivery and resistance to nuclease degradation, the nanoprobe has been successfully applied for microRNA imaging in live cells.

Graphical abstract: A self-delivery DNA nanoprobe for reliable microRNA imaging in live cells by aggregation induced red-shift-emission

Supplementary files

Article information

Article type
Communication
Submitted
15 Okt. 2019
Accepted
23 Dec. 2019
First published
28 Dec. 2019

Chem. Commun., 2020,56, 1501-1504

A self-delivery DNA nanoprobe for reliable microRNA imaging in live cells by aggregation induced red-shift-emission

Z. Chen, J. Lu, F. Xiao, Y. Huang, X. Zhang and L. Tian, Chem. Commun., 2020, 56, 1501 DOI: 10.1039/C9CC08093G

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