Issue 4, 2019

Use of plant hormones to activate silent polyketide biosynthetic pathways in Arthrinium sacchari, a fungus isolated from a spider

Abstract

Plant hormones were evaluated for their ability to activate fungal secondary metabolite production. Three synthetic cytokinins, kinetin, 6-benzylaminopurine, and forchlorfenuron, showed remarkable enhancement of the production of aromatic polyketides derived from emodin in a fungus, Arthrinium sacchari, and allowed us to isolate a new polyketide. Furthermore, we firstly demonstrated the potential of plant hormones to activate a wide range of fungal secondary metabolite production processes.

Graphical abstract: Use of plant hormones to activate silent polyketide biosynthetic pathways in Arthrinium sacchari, a fungus isolated from a spider

  • This article is part of the themed collection: Biosynthesis

Supplementary files

Article information

Article type
Communication
Submitted
14 Nov. 2018
Accepted
19 Dec. 2018
First published
20 Dec. 2018

Org. Biomol. Chem., 2019,17, 780-784

Use of plant hormones to activate silent polyketide biosynthetic pathways in Arthrinium sacchari, a fungus isolated from a spider

Y. Morishita, Y. Okazaki, Y. Y. Luo, J. Nunoki, T. Taniguchi, Y. Oshima and T. Asai, Org. Biomol. Chem., 2019, 17, 780 DOI: 10.1039/C8OB02837K

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