Issue 10, 2018

Fast-forming BMSC-encapsulating hydrogels through bioorthogonal reaction for osteogenic differentiation

Abstract

An injectable in situ fast-forming hydrogel was easily fabricated through the inverse electron demand Diels–Alder click reaction between trans-cyclooctene and tetrazine. This hydrogel system simultaneously encapsulated bone morphogenetic protein-2 and BMSCs which showed potential applications in 3D bio-printing and tissue engineering.

Graphical abstract: Fast-forming BMSC-encapsulating hydrogels through bioorthogonal reaction for osteogenic differentiation

Supplementary files

Article information

Article type
Communication
Submitted
21 Jūn. 2018
Accepted
20 Aug. 2018
First published
21 Aug. 2018

Biomater. Sci., 2018,6, 2578-2581

Fast-forming BMSC-encapsulating hydrogels through bioorthogonal reaction for osteogenic differentiation

Y. Zhang, H. Chen, T. Zhang, Y. Zan, T. Ni, M. Liu and R. Pei, Biomater. Sci., 2018, 6, 2578 DOI: 10.1039/C8BM00689J

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