Issue 53, 2017

Cell-sized mechanosensitive and biosensing compartment programmed with DNA

Abstract

The bottom-up construction of cell-sized compartments programmed with DNA that are capable of sensing the chemical and physical environment remains challenging in synthetic cell engineering. Here, we construct mechanosensitive liposomes with biosensing capability by expressing the E. coli channel MscL and a calcium biosensor using cell-free expression.

Graphical abstract: Cell-sized mechanosensitive and biosensing compartment programmed with DNA

Supplementary files

Article information

Article type
Communication
Submitted
04 Maijs 2017
Accepted
12 Maijs 2017
First published
12 Maijs 2017

Chem. Commun., 2017,53, 7349-7352

Cell-sized mechanosensitive and biosensing compartment programmed with DNA

S. Majumder, J. Garamella, Y. Wang, M. DeNies, V. Noireaux and A. P. Liu, Chem. Commun., 2017, 53, 7349 DOI: 10.1039/C7CC03455E

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