Issue 26, 2016

Improved chemical and mechanical stability of peptoid nanosheets by photo-crosslinking the hydrophobic core

Abstract

Peptoid nanosheets can be broadly functionalized for a variety of applications. However, they are susceptible to degradation when exposed to chemical or mechanical stress. To improve their strength, photolabile monomers were introduced in order to crosslink the nanosheet interior. Photo-crosslinking produced a more robust material that can survive sonication, lyophilization, and other biochemical manipulations.

Graphical abstract: Improved chemical and mechanical stability of peptoid nanosheets by photo-crosslinking the hydrophobic core

  • This article is part of the themed collection: Foldamers

Supplementary files

Article information

Article type
Communication
Submitted
21 Janv. 2016
Accepted
05 Febr. 2016
First published
05 Febr. 2016

Chem. Commun., 2016,52, 4753-4756

Improved chemical and mechanical stability of peptoid nanosheets by photo-crosslinking the hydrophobic core

D. Flood, C. Proulx, E. J. Robertson, A. Battigelli, S. Wang, A. M. Schwartzberg and R. N. Zuckermann, Chem. Commun., 2016, 52, 4753 DOI: 10.1039/C6CC00588H

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