Issue 27, 2024

Tuneable redox-responsive albumin-hitchhiking drug delivery to tumours for cancer treatment

Abstract

This paper outlines a novel drug delivery system for highly cytotoxic mertansine (DM1) by conjugating to an albumin-binding Evans blue (EB) moiety through a tuneable responsive disulfide linker, providing valuable insights for the development of effective drug delivery systems toward cancer therapy.

Graphical abstract: Tuneable redox-responsive albumin-hitchhiking drug delivery to tumours for cancer treatment

Supplementary files

Article information

Article type
Communication
Submitted
06 Apr. 2024
Accepted
11 Jūn. 2024
First published
20 Jūn. 2024
This article is Open Access
Creative Commons BY-NC license

J. Mater. Chem. B, 2024,12, 6563-6569

Tuneable redox-responsive albumin-hitchhiking drug delivery to tumours for cancer treatment

S. Fu, A. Zheng, L. Wang, J. Chen, B. Zhao, X. Zhang, V. A. A. McKenzie, Z. Yang, R. M. Leblanc, R. Prabhakar and F. Zhang, J. Mater. Chem. B, 2024, 12, 6563 DOI: 10.1039/D4TB00751D

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements