Issue 12, 2024

An organic brain-inspired platform with neurotransmitter closed-loop control, actuation and reinforcement learning

Abstract

Organic neuromorphic platforms have recently received growing interest for the implementation and integration of artificial and hybrid neuronal networks. Here, achieving closed-loop and learning/training processes as in the human brain is still a major challenge especially exploiting time-dependent biosignalling such as neurotransmitter release. Here, we present an integrated organic platform capable of cooperating with standard silicon technologies, to achieve brain-inspired computing via adaptive synaptic potentiation and depression, in a closed-loop fashion. The microfabricated platform could be interfaced and control a robotic hand which ultimately was able to learn the grasping of differently sized objects, autonomously.

Graphical abstract: An organic brain-inspired platform with neurotransmitter closed-loop control, actuation and reinforcement learning

Supplementary files

Article information

Article type
Communication
Submitted
20 Dec. 2023
Accepted
25 Marts 2024
First published
30 Apr. 2024
This article is Open Access
Creative Commons BY license

Mater. Horiz., 2024,11, 2865-2874

An organic brain-inspired platform with neurotransmitter closed-loop control, actuation and reinforcement learning

U. Bruno, D. Rana, C. Ausilio, A. Mariano, O. Bettucci, S. Musall, C. Lubrano and F. Santoro, Mater. Horiz., 2024, 11, 2865 DOI: 10.1039/D3MH02202A

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