Issue 4, 2024

Therapeutic synthetic and natural materials for immunoengineering

Abstract

Immunoengineering is a rapidly evolving field that has been driving innovations in manipulating immune system for new treatment tools and methods. The need for materials for immunoengineering applications has gained significant attention in recent years due to the growing demand for effective therapies that can target and regulate the immune system. Biologics and biomaterials are emerging as promising tools for controlling immune responses, and a wide variety of materials, including proteins, polymers, nanoparticles, and hydrogels, are being developed for this purpose. In this review article, we explore the different types of materials used in immunoengineering applications, their properties and design principles, and highlight the latest therapeutic materials advancements. Recent works in adjuvants, vaccines, immune tolerance, immunotherapy, and tissue models for immunoengineering studies are discussed.

Graphical abstract: Therapeutic synthetic and natural materials for immunoengineering

Article information

Article type
Review Article
Submitted
22 Sept. 2023
First published
03 Janv. 2024
This article is Open Access
Creative Commons BY license

Chem. Soc. Rev., 2024,53, 1789-1822

Therapeutic synthetic and natural materials for immunoengineering

A. Slezak, K. Chang, S. Hossainy, A. Mansurov, S. J. Rowan, J. A. Hubbell and M. O. Guler, Chem. Soc. Rev., 2024, 53, 1789 DOI: 10.1039/D3CS00805C

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