Issue 73, 2023

Diverging conformations guide dipeptide self-assembly into crystals or hydrogels

Abstract

The prediction of dipeptide assembly into crystals or gels is challenging. This work reveals the diverging conformational landscape that guides self-organization towards different outcomes. In silico and experimental data enabled deciphering of the electronic circular dichroism (ECD) spectra of self-assembling dipeptides to reveal folded or extended conformers as key players.

Graphical abstract: Diverging conformations guide dipeptide self-assembly into crystals or hydrogels

Supplementary files

Article information

Article type
Communication
Submitted
09 Jūn. 2023
Accepted
14 Aug. 2023
First published
15 Aug. 2023

Chem. Commun., 2023,59, 10948-10951

Diverging conformations guide dipeptide self-assembly into crystals or hydrogels

M. Monti, E. Scarel, A. Hassanali, M. Stener and S. Marchesan, Chem. Commun., 2023, 59, 10948 DOI: 10.1039/D3CC02682E

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