Issue 14, 2022

Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly

Abstract

In order to develop new three-dimensional (3D) cell culture systems for articular cartilage regeneration, concentrated poly(styrene sulfonate sodium salt) brush-modified cellulose nanofibers were employed as building blocks for the self-assembly of human mesenchymal stem cells (hMSCs). Unique 3D cellular structures, such as giant spheres and sheets, were formed by controlling hMSC self-assembly.

Graphical abstract: Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly

Supplementary files

Article information

Article type
Communication
Submitted
21 Okt. 2021
Accepted
11 Janv. 2022
First published
19 Janv. 2022

J. Mater. Chem. B, 2022,10, 2444-2453

Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly

P. Nonsuwan, N. Nishijima, K. Sakakibara, T. Nakaji-Hirabayashi and C. Yoshikawa, J. Mater. Chem. B, 2022, 10, 2444 DOI: 10.1039/D1TB02307A

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