Issue 23, 2022

Recent developments in enantioselective nickel(ii)-catalyzed conjugate additions

Abstract

This review highlights the recent developments in enantioselective nickel-catalyzed conjugate additions of various nucleophiles to numerous acceptor-activated olefins published since 2016. By the very fact of the lower costs of nickel catalysts in comparison with other transition metals, these reactions represent powerful and economic methodologies for the stereocontrolled formation of carbon–carbon and carbon-heteroatom bonds. When applied to initiate domino reactions, these processes allowed a direct access to a variety of complex and functionalized chiral molecules.

Graphical abstract: Recent developments in enantioselective nickel(ii)-catalyzed conjugate additions

Article information

Article type
Review Article
Submitted
01 Jūl. 2022
Accepted
23 Okt. 2022
First published
24 Okt. 2022

Org. Chem. Front., 2022,9, 6717-6748

Recent developments in enantioselective nickel(II)-catalyzed conjugate additions

H. Pellissier, Org. Chem. Front., 2022, 9, 6717 DOI: 10.1039/D2QO01047J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements