Issue 9, 2022

Visible-light-driven photoredox-catalyzed C(sp3)–C(sp3) cross-coupling of N-arylamines with cycloketone oxime esters

Abstract

A novel photoredox-catalyzed C(sp3)–C(sp3) cross-coupling between N-arylamines and cycloketone oxime esters under mild conditions has been accomplished. The redox-neutral reaction proceeds with good functional group tolerance and excellent regioselectivity without any extra base or ligand control. In addition, this approach was successfully applied for the late-stage modification of short peptides and analogues.

Graphical abstract: Visible-light-driven photoredox-catalyzed C(sp3)–C(sp3) cross-coupling of N-arylamines with cycloketone oxime esters

Supplementary files

Article information

Article type
Research Article
Submitted
24 Janv. 2022
Accepted
22 Marts 2022
First published
24 Marts 2022

Org. Chem. Front., 2022,9, 2534-2540

Visible-light-driven photoredox-catalyzed C(sp3)–C(sp3) cross-coupling of N-arylamines with cycloketone oxime esters

S. Zhou, D. Zhang, X. Liu, J. Qin, Z. Fu, S. Li, F. Cai, Y. Li and J. Li, Org. Chem. Front., 2022, 9, 2534 DOI: 10.1039/D2QO00128D

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