Issue 8, 2022

Visible-light-promoted radical amidoarylation of arylacrylamides towards amidated oxindoles

Abstract

A visible-light-promoted intermolecular radical amidation/cyclization of arylacrylamides was realized by using N-aminopyridinium salts as the source of amidyl radicals. The reaction exhibits a broad scope and good functional group tolerance, and a variety of amide-tethered-oxindoles were prepared in this way in moderate to good yields.

Graphical abstract: Visible-light-promoted radical amidoarylation of arylacrylamides towards amidated oxindoles

Supplementary files

Article information

Article type
Research Article
Submitted
24 Janv. 2022
Accepted
25 Febr. 2022
First published
28 Febr. 2022

Org. Chem. Front., 2022,9, 2164-2168

Visible-light-promoted radical amidoarylation of arylacrylamides towards amidated oxindoles

Y. Wang, W. Lin, H. Liu and W. Yu, Org. Chem. Front., 2022, 9, 2164 DOI: 10.1039/D2QO00127F

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