Issue 29, 2022

Nucleic acid isothermal amplification-based soft nanoarchitectonics as an emerging electrochemical biosensing platform

Abstract

The emergence of nucleic acid isothermal amplification strategies based on soft nanoarchitectonics offers a new dimension to the traditional electrochemical technique, particularly because of its flexibility, high efficiency, and increased sensitivity for analytical applications. Various DNA/RNA isothermal amplification strategies have been developed for the design and fabrication of new electrochemical biosensors for efficient and important biomolecular detection. Herein, we provide an overview of recent efforts in this research field and the strategies for signal-amplified sensing systems, with their biological applications, current challenges and prospects in this promising new area.

Graphical abstract: Nucleic acid isothermal amplification-based soft nanoarchitectonics as an emerging electrochemical biosensing platform

Article information

Article type
Review Article
Submitted
13 Apr. 2022
Accepted
20 Jūn. 2022
First published
20 Jūn. 2022

Nanoscale, 2022,14, 10286-10298

Nucleic acid isothermal amplification-based soft nanoarchitectonics as an emerging electrochemical biosensing platform

J. Liu, R. Wang, H. Zhou, M. Mathesh, M. Dubey, W. Zhang, B. Wang and W. Yang, Nanoscale, 2022, 14, 10286 DOI: 10.1039/D2NR02031A

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