Issue 10, 2022

Three-dimensional artificial chirality towards low-cost and ultra-sensitive enantioselective sensing

Abstract

Artificial chiral structures have potential applications in the field of enantioselective signal sensing. Advanced nanofabrication methods enable a large diversity in geometric structures and broad selectivity of materials, which can be exploited to manufacture artificial three-dimensional chiral structures. Various chiroptical phenomena exploiting spin and orbital angular momentum at the nanoscale have been continuously exploited as a way to effectively detect enantiomers. This review introduces precisely controlled bottom-up and large-area top-down metamaterial fabrication methods to solve the limitations of high manufacturing cost and low production speed. Particle synthesis, self-assembly, glanced angled vapor deposition, and three-dimensional plasmonic nanostructure printing are introduced. Furthermore, emerging sensitive chiral sensing methods such as cavity-enhanced chirality, photothermal circular dichroism, and helical dichroism of single particles are discussed. The continuous progress of nanofabrication technology presents the strong potential for developing artificial chiral structures for applications in biomedical, pharmaceutical, nanophotonic systems.

Graphical abstract: Three-dimensional artificial chirality towards low-cost and ultra-sensitive enantioselective sensing

Article information

Article type
Minireview
Submitted
03 Sept. 2021
Accepted
24 Nov. 2021
First published
29 Nov. 2021

Nanoscale, 2022,14, 3720-3730

Three-dimensional artificial chirality towards low-cost and ultra-sensitive enantioselective sensing

Y. Kim, H. Kim, Y. Yang, T. Badloe, N. Jeon and J. Rho, Nanoscale, 2022, 14, 3720 DOI: 10.1039/D1NR05805C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements