Issue 33, 2021

Hydrogel, a novel therapeutic and delivery strategy, in the treatment of intrauterine adhesions

Abstract

Intrauterine adhesions (IUAs) are caused by damage to the underlying lining of the endometrium. They’ re related to disorder of endometrial repair. In recent years, hydrogels with controllable biological activity have been widely used for treating IUAs. They encapsulate estrogen, cytokines, cells, or exosomes, forming a delivery system to release therapeutic components for the treatment of IUAs. In addition, the hydrogel acting as a barrier can be degraded in the body automatically, reducing the risk of infection caused by secondary surgeries. In this review, we summarize the recent progress of hydrogels and their application in IUAs as both a novel alternative therapeutic and an artificial delivery strategy.

Graphical abstract: Hydrogel, a novel therapeutic and delivery strategy, in the treatment of intrauterine adhesions

Article information

Article type
Review Article
Submitted
05 Maijs 2021
Accepted
16 Jūl. 2021
First published
22 Jūl. 2021

J. Mater. Chem. B, 2021,9, 6536-6552

Hydrogel, a novel therapeutic and delivery strategy, in the treatment of intrauterine adhesions

H. Lv, B. Wu, J. Song, W. Wu, W. Cai and J. Xu, J. Mater. Chem. B, 2021, 9, 6536 DOI: 10.1039/D1TB01005K

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