Issue 15, 2021

Acyl metalloids: conformity and deviation from carbonyl reactivity

Abstract

Once considered as mere curiosities, acyl metalloids are now recognized for their utility in enabling chemical synthesis. This perspective considers the reactivity displayed by acylboron, -silicon, -germanium, and tellurium species. By highlighting the role of these species in various transformations, we demonstrate how differences between the comprising elements result in varied reaction outcomes. While acylboron compounds are primarily used in polar transformations, germanium and tellurium species have found utility as radical precursors. Applications of acylsilanes are comparatively more diverse, owing to the possibility to access both radical and polar chemistry.

Graphical abstract: Acyl metalloids: conformity and deviation from carbonyl reactivity

Article information

Article type
Perspective
Submitted
06 Janv. 2021
Accepted
09 Marts 2021
First published
10 Marts 2021
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2021,12, 5346-5360

Acyl metalloids: conformity and deviation from carbonyl reactivity

A. Holownia, C. N. Apte and A. K. Yudin, Chem. Sci., 2021, 12, 5346 DOI: 10.1039/D1SC00077B

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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