Issue 22, 2021

Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection of Staphylococcus aureus

Abstract

This paper reports a colorimetric-fluorescent dual-signal lateral flow assay (LFA) based on vancomycin (Van)-modified SiO2–Au-QD tags for sensitive and quantitative detection of Staphylococcus aureus (S. aureus). The combination of high-performance Van-tags and detection antibodies integrated into the LFA system produced assays with high sensitivity and specificity. The visualization limit of the colorimetric signal and the detection limit of the fluorescence signal of the proposed method for S. aureus can reach 104 and 100 cells mL−1, respectively.

Graphical abstract: Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection of Staphylococcus aureus

Supplementary files

Article information

Article type
Paper
Submitted
09 Febr. 2021
Accepted
28 Marts 2021
First published
09 Apr. 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 13297-13303

Dual-signal lateral flow assay using vancomycin-modified nanotags for rapid and sensitive detection of Staphylococcus aureus

S. Wang, W. Shen, S. Zheng, Z. Li, C. Wang, L. Zhang and Y. Liu, RSC Adv., 2021, 11, 13297 DOI: 10.1039/D1RA01085A

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