Issue 10, 2021

Photodynamic therapy: photosensitizers and nanostructures

Abstract

The reactions of some structures to different external stimuli can be used for therapeutic purposes. In particular, in photodynamic therapy (PDT), a light-sensitive compound or structure, commonly named a photosensitizer (PS), is able to produce reactive oxygen species (ROS) after being irradiated with light in the presence of oxygen. Such ROS are effective in destroying cells and can be used as therapeutic agents to treat some skin and eye diseases, as well as certain types of cancer. This review will summarise the current state-of-the-art in PDT, with special focus on the different available photosensitizers, their chemistry, their incorporation into different nanostructures, and some of the current targeting strategies.

Graphical abstract: Photodynamic therapy: photosensitizers and nanostructures

Article information

Article type
Review Article
Submitted
12 Nov. 2020
Accepted
08 Febr. 2021
First published
26 Febr. 2021
This article is Open Access
Creative Commons BY-NC license

Mater. Chem. Front., 2021,5, 3788-3812

Photodynamic therapy: photosensitizers and nanostructures

A. Escudero, C. Carrillo-Carrión, M. xmlns="http://www.rsc.org/schema/rscart38"> <. C. Castillejos, E. Romero-Ben, C. Rosales-Barrios and N. Khiar, Mater. Chem. Front., 2021, 5, 3788 DOI: 10.1039/D0QM00922A

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements