Issue 35, 2021
From the journal:

Organic & Biomolecular Chemistry

The biology and total syntheses of bisbenzylisoquinoline alkaloids

Viviene K. Nguyen ORCID logo a  and  Kevin. G. M. Kou ORCID logo *a  

* Corresponding authors

a Department of Chemistry, University of California, Riverside, California 92521, USA
E-mail: kevink@ucr.edu

Abstract

This mini-review provides a concise overview of the biosynthetic pathway and pharmacology of bisbenzylisoquinoline alkaloid (bisBIA) natural products. Additional emphasis is given to the methodologies in the total syntheses of both simpler acyclic diaryl ether dimers and their macrocyclic counterparts bearing two diaryl ether linkages.

Graphical abstract: The biology and total syntheses of bisbenzylisoquinoline alkaloids

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Article information

DOI
https://doi.org/10.1039/D1OB00812A
Article type
Review Article
Submitted
26 Apr. 2021
Accepted
21 Jūl. 2021
First published
17 Aug. 2021

Org. Biomol. Chem., 2021,19, 7535-7543

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The biology and total syntheses of bisbenzylisoquinoline alkaloids

V. K. Nguyen and Kevin. G. M. Kou, Org. Biomol. Chem., 2021, 19, 7535 DOI: 10.1039/D1OB00812A

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