Issue 37, 2021

Thermally induced silane dehydrocoupling on porous silicon nanoparticles for ultra-long-acting drug release

Abstract

Here, we report an ultra-long-acting drug release nano-formulation based on porous silicon nanoparticles (pSiNPs) that are prepared by thermally induced silane dehydrocoupling and lipid-coating. This robust formulation offers the ability to release an anticancer drug, for up to 2 weeks, in various biological environments; pH 7.4 buffer, cancer cells, and tumor xenograft model.

Graphical abstract: Thermally induced silane dehydrocoupling on porous silicon nanoparticles for ultra-long-acting drug release

Supplementary files

Article information

Article type
Communication
Submitted
21 Maijs 2021
Accepted
04 Aug. 2021
First published
20 Aug. 2021

Nanoscale, 2021,13, 15560-15568

Thermally induced silane dehydrocoupling on porous silicon nanoparticles for ultra-long-acting drug release

J. H. Oh, R. H. Kang, J. Kim, E. Bang and D. Kim, Nanoscale, 2021, 13, 15560 DOI: 10.1039/D1NR03263A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements