Issue 24, 2021

Recent advances of vibrational spectroscopy and chemometrics for forensic biological analysis

Abstract

Biological materials found at a crime scene are crucially important evidence for forensic investigation because they provide contextual information about a crime and can be linked to the donor-individuals through combination with DNA analysis. Applications of vibrational spectroscopy to forensic biological analysis have been emerging because of its advantageous characteristics such as the non-destructivity, rapid measurement, and quantitative evaluation, compared to most current methods based on histological observation or biochemical techniques. This review presents an overview of recent developments in vibrational spectroscopy for forensic biological analysis. We also emphasize chemometric techniques, which can elicit reliable and advanced analytical outputs from highly complex spectral data from forensic biological materials. The analytical subjects addressed herein include body fluids, hair, soft tissue, bones, and bioagents. Promising applications for various analytical purposes in forensic biology are presented. Simultaneously, future avenues of study requiring further investigation are discussed.

Graphical abstract: Recent advances of vibrational spectroscopy and chemometrics for forensic biological analysis

Article information

Article type
Critical Review
Submitted
07 Sept. 2021
Accepted
14 Nov. 2021
First published
16 Nov. 2021

Analyst, 2021,146, 7431-7449

Author version available

Recent advances of vibrational spectroscopy and chemometrics for forensic biological analysis

A. Takamura and T. Ozawa, Analyst, 2021, 146, 7431 DOI: 10.1039/D1AN01637G

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