Issue 4, 2020

3D printing of a poly(vinyl alcohol)-based nano-composite hydrogel as an artificial cartilage replacement and the improvement mechanism of printing accuracy

Abstract

Inspired by the gradient structure of articular cartilage, a poly(vinyl alcohol) (PVA)-based composite hydrogel with a biomimetic gradient structure as an artificial cartilage replacement was constructed by an extrusion 3D printing technique. The influence of the concentration and composition of the PVA-based solution on its rheological behavior and printability was studied, and the improvement mechanism for the 3D printing accuracy of the hydrogel was explored: introduction of GO or GO–HA gave rise to weakened inter-molecular hydrogen bonds and reduced entanglement density simultaneously, and the dynamic viscosity was highly improved. Therefore, the solution exhibited enhanced shear-thinning behavior in the printing shear rate range and a reduced Barus effect, thus highly improving the printability and printing accuracy of the samples. The 3D printing of PVA hydrogels was successfully achieved, and the printed biomimetic gradient samples possessed suitable compressive and tribological properties, which showed promising potential in the precise customized repair of artificial cartilage.

Graphical abstract: 3D printing of a poly(vinyl alcohol)-based nano-composite hydrogel as an artificial cartilage replacement and the improvement mechanism of printing accuracy

Article information

Article type
Paper
Submitted
15 Okt. 2019
Accepted
04 Dec. 2019
First published
05 Dec. 2019

J. Mater. Chem. B, 2020,8, 677-690

3D printing of a poly(vinyl alcohol)-based nano-composite hydrogel as an artificial cartilage replacement and the improvement mechanism of printing accuracy

Y. Meng, J. Cao, Y. Chen, Y. Yu and L. Ye, J. Mater. Chem. B, 2020, 8, 677 DOI: 10.1039/C9TB02278C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements