Issue 49, 2020

Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes

Abstract

An efficient [4 + 2] benzannulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes was achieved under metal-free reaction conditions selectively delivering a wide range of polyfunctional benzenes in high yields respectively (up to 94% yield).

Graphical abstract: Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes

Supplementary files

Article information

Article type
Paper
Submitted
15 Jūn. 2020
Accepted
28 Jūl. 2020
First published
06 Aug. 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 29171-29174

Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes

Q. Jia, Y. Lan, X. Ye, Y. Lin and Q. Ren, RSC Adv., 2020, 10, 29171 DOI: 10.1039/D0RA05251E

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