Issue 42, 2020

Iodine-catalyzed efficient synthesis of xanthene/thioxanthene-indole derivatives under mild conditions

Abstract

An iodine-catalyzed nucleophilic substitution reaction of xanthen-9-ol and thioxanthen-9-ol with indoles has been developed, providing an efficient procedure for the synthesis of xanthene/thioxanthene-indole derivatives with good to excellent yields. This protocol offers several advantages, such as short reaction times, green solvent, operational simplicity, easily available catalyst and mild reaction conditions. Moreover, this method showed good tolerance of functional groups and a wide range of substrates.

Graphical abstract: Iodine-catalyzed efficient synthesis of xanthene/thioxanthene-indole derivatives under mild conditions

Supplementary files

Article information

Article type
Paper
Submitted
13 Jūn. 2020
Accepted
26 Jūn. 2020
First published
02 Jūl. 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 25165-25169

Iodine-catalyzed efficient synthesis of xanthene/thioxanthene-indole derivatives under mild conditions

W. Miao, P. Ye, M. Bai, Z. Yang, S. Duan, H. Duan and X. Wang, RSC Adv., 2020, 10, 25165 DOI: 10.1039/D0RA05217E

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements