Issue 65, 2020

A sodium alginate-based sustained-release IPN hydrogel and its applications

Abstract

Interpenetrating polymer network (IPN) hydrogels are crosslinked by two or more polymer networks, providing free volume space in the three-dimensional network structure, and providing conditions for the sustained and controlled release of drugs. The IPN hydrogels based on the natural polymer sodium alginate can form a stable porous network structure. Due to its excellent biocompatibility, the loaded drug can be sustained to the maximum extent without affecting its pharmacological effect. Sodium alginate-based IPN hydrogels have broad application prospects in the field of sustained and controlled drug release. This paper begins with an overview of the formation of alginate-based IPN hydrogels; summarizes the types of alginate-based IPN hydrogels; and discusses the pharmaceutical applications of alginate-based IPN hydrogels. We aim to give an overview of the research on IPN hydrogels based on sodium alginate in sustained and controlled drug release systems.

Graphical abstract: A sodium alginate-based sustained-release IPN hydrogel and its applications

Article information

Article type
Review Article
Submitted
14 Maijs 2020
Accepted
19 Okt. 2020
First published
30 Okt. 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 39722-39730

A sodium alginate-based sustained-release IPN hydrogel and its applications

Z. Zou, B. Zhang, X. Nie, Y. Cheng, Z. Hu, M. Liao and S. Li, RSC Adv., 2020, 10, 39722 DOI: 10.1039/D0RA04316H

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements